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| | best-11 | Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (444 aa) |
| | best-26 | Bestrophin homolog 26; Forms chloride channels. (411 aa) |
| | best-25 | Bestrophin homolog 25; Forms chloride channels. (602 aa) |
| | best-23 | Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (405 aa) |
| | eat-4 | Probable vesicular glutamate transporter eat-4; Required for glutamatergic synaptic transmission. In AWB and AWC sensory neurons, required for the detection of preferred food sources, probably via glutamatergic neurotransmission from sensory neurons. Negatively regulates the turning step of male mating behavior. (576 aa) |
| | shk-1 | Potassium voltage-gated channel protein shk-1; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Has an important role in repolarization and in regulating the pattern of action potential firing. Isoform a expresses currents in a more depolarized voltage range than isoform d. (536 aa) |
| | tax-4 | Cyclic nucleotide-gated cation channel; Required for normal thermosensation and chemosensation sensory behavior. Required, downstream of receptor- type guanylate cyclase gcy-9, for CO2-mediated responses in BAG neurons. Required, downstream of receptor-type guanylate cyclase gcy-14, for alkaline pH-mediated responses in ASE-left (ASEL) neurons. Involved in the development of ASJ sensory neuron axon during late larval stages and in the maintenance of normal axon morphology in the adult. Regulates dauer formation. Required for the calcium flux to the cytoplasm in the ASJ sensory neurons [...] (733 aa) |
| | best-22 | Bestrophin homolog 22; Forms chloride channels. (510 aa) |
| | ZC477.3 | Uncharacterized protein. (330 aa) |
| | cng-2 | Cyclic nucleotide-binding domain-containing protein. (819 aa) |
| | best-21 | Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (395 aa) |
| | micu-1 | Calcium uptake protein 1 homolog, mitochondrial; Key regulator of mitochondrial calcium uniporter (MCU). (534 aa) |
| | eat-2 | Neuronal acetylcholine receptor subunit eat-2; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). Nicotinic acetylcholine receptor in the MC pharyngeal motor neuron involved in pharyngeal pumping. Has a role in the determination of life span possibly via calorific restriction which affects growth rate, although this is independent of metabolic activity. Plays a role in the defense against the accumulation of ingested live pathogenic [...] (474 aa) |
| | kvs-4 | Probable voltage-gated potassium channel subunit kvs-4; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. (512 aa) |
| | best-20 | Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (486 aa) |
| | Y12A6A.1 | Uncharacterized protein. (209 aa) |
| | exc-4 | Chloride intracellular channel exc-4; May insert into membranes and form chloride ion channels. Involved in the formation of the excretory canal. Required to prevent cystic lumenal expansions in the excretory cell. Not required for formation of the initial tube, but is required for regulating the size of the tube lumen as it grows. (290 aa) |
| | ccb-2 | SH3 domain-containing protein. (396 aa) |
| | zipt-7.1 | Zinc transporter zipt-7.1; Zinc transporter which regulates intracellular zinc levels. Required for spermatogenesis in both hermaphrodites and males where it resides in an inactive form in immature sperm, spermatids, but is likely activated in response to reduced spe-4 and spe-6 function. Upon activation, mediates the release of zinc from internal stores in spermatids into the cytoplasm. The resulting increase in cytoplasmic zinc levels promotes spermatid activation and subsequent differentiation into mature motile sperm that are capable of fertilization. (393 aa) |
| | ccb-1 | GuKc domain-containing protein. (526 aa) |
| | tag-180 | VWFA domain-containing protein. (1067 aa) |
| | best-19 | Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (569 aa) |
| | best-18 | Bestrophin homolog 18; Forms chloride channels. (456 aa) |
| | lgc-50 | Ligand-gated ion channel 50. (491 aa) |
| | T19C3.3 | Uncharacterized protein T19C3.3. (92 aa) |
| | best-17 | Bestrophin homolog 17; Forms chloride channels. (501 aa) |
| | T19B10.2 | Uncharacterized protein. (368 aa) |
| | unc-2 | EF-hand domain-containing protein. (2171 aa) |
| | shw-3 | BTB domain-containing protein; Belongs to the potassium channel family. (500 aa) |
| | best-16 | Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (463 aa) |
| | best-15 | Bestrophin homolog 15; Forms chloride channels. (525 aa) |
| | egl-36 | Potassium voltage-gated channel protein egl-36; Voltage-dependent potassium channel involved in the excitation of muscles operating egg-laying and defecation. Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Shaw sub-subfamily. (558 aa) |
| | trp-2 | TRP (Transient receptor potential) channel family; Belongs to the transient receptor (TC 1.A.4) family. (886 aa) |
| | R02D5.3 | Uncharacterized protein. (258 aa) |
| | irk-2 | Inward Rectifying K (Potassium) channel family. (497 aa) |
| | unc-68 | Uncharacterized protein. (5202 aa) |
| | mod-1 | Serotonin-gated chloride channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (489 aa) |
| | sol-2 | Suppressor Of Lurcher movement defect. (436 aa) |
| | irk-3 | IRK_C domain-containing protein. (384 aa) |
| | neto-1 | NETO (NEuropilin and TOlloid-like) homolog. (368 aa) |
| | mcu-1 | Calcium uniporter protein, mitochondrial; Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore- forming and calcium-conducting subunit (By similarity). Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways (By similarity). Required for rapid mitochondrial calcium uptake and mitochondrial reactive oxygen species (mtROS) production after wounding. (333 aa) |
| | zipt-7.2 | Zinc transporter zipt-7.2; Zinc transporter. (462 aa) |
| | kvs-3 | Uncharacterized protein; Belongs to the potassium channel family. (451 aa) |
| | csq-1 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (417 aa) |
| | cng-3 | Cyclic nucleotide-binding domain-containing protein. (626 aa) |
| | tax-2 | Cyclic nucleotide-binding domain-containing protein. (800 aa) |
| | itr-1 | Inositol 1,4,5-trisphosphate receptor itr-1; Receptor for inositol 1,4,5-trisphosphate, a second messenger that regulates intracellular calcium homeostasis. Binds in vitro to both inositol 1,4,5-trisphosphate (1,4,5-InsP3) and inositol 2,4,5-trisphosphate (2,4,5-InsP3) with high affinity and does not discriminate between the phosphate at 1 or 2 position. Can also bind inositol 1,3,4,5-tetrakisphosphate (1,3,4,5-InsP4) and inositol 4,5-bisphosphate (4,5-InsP2), but with lower affinity. Acts as a timekeeper/rhythm generator via calcium signaling, affecting the defecation cycle and pharyn [...] (2892 aa) |
| | best-14 | Bestrophin homolog 14. (405 aa) |
| | best-13 | Bestrophin homolog 13; Forms chloride channels. (413 aa) |
| | glc-2 | Glutamate-gated chloride channel subunit beta; Glutamate-gated chloride channel subunit; channel properties depend on the subunit composition. Glutamate binding triggers a rapidly reversible current in heteromeric channels formed by glc-1 and glc-2, while the anti-helmintic drug ivermectin and other avermectins trigger a permanently open channel configuration. Channels containing only glc- 2 are activated by glutamate, but not by ivermectin (in vitro). The heteromeric channel formed by glc-1 and glc-2 is also activated by ibotenate, and it is blocked by picrotoxin and flufenamic acid. (434 aa) |
| | unc-80 | Protein unc-80; Probable component of the nca-1 sodium channel complex, a cation channel that regulates neuronal activity by transmitting depolarization signals to synapses. Regulates the transition from slow to rapid forms of locomotion. Required for localization of nca-1 along axons and in non-synaptic regions. Contributes to endocytosis defects in synaptojanin mutants. Involved in the control of anasthetic response to halothane. (3263 aa) |
| | emre-1 | Essential MCU regulator, mitochondrial; Essential regulatory subunit of the mitochondrial calcium uniporter (mcu-1) channel, a protein that mediates calcium uptake into mitochondria; Belongs to the SMDT1/EMRE family. (90 aa) |
| | cng-1 | Cyclic nucleotide-binding domain-containing protein. (661 aa) |
| | best-12 | Bestrophin homolog 12; Forms chloride channels. (434 aa) |
| | exp-2 | Uncharacterized protein; Belongs to the potassium channel family. (510 aa) |
| | stg-2 | STarGazin (Mammalian calcium channel) homolog. (379 aa) |
| | molo-1 | Uncharacterized protein. (298 aa) |
| | nmr-1 | NMDA-type ionotropic glutamate receptor NMR-1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1025 aa) |
| | C56A3.6 | Uncharacterized protein. (477 aa) |
| | cca-1 | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (1885 aa) |
| | kvs-1 | Uncharacterized protein; Belongs to the potassium channel family. (495 aa) |
| | unc-36 | Voltage-dependent calcium channel unc-36; May act as an auxiliary subunit of the unc-2 voltage-gated calcium channel which appears to trigger calcium-activated signaling pathways that control the serotonin response. Inhibiting serotonin sensitivity of the vulval muscles results in egg laying defects. May act in both neurons and muscle cells to enhance motor activity as it is required for coordinated movement. Has a role in neural depolarization- induced calcium influx and pharyngeal pumping. Involved in restricting the expression of the putative olfactory receptor str-2 to only one of [...] (1249 aa) |
| | best-10 | Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (423 aa) |
| | egl-19 | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1877 aa) |
| | best-9 | Bestrophin homolog 9; Forms chloride channels. (399 aa) |
| | acr-9 | AcetylCholine Receptor. (534 aa) |
| | best-8 | Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (512 aa) |
| | C32C4.1 | BTB domain-containing protein; Belongs to the potassium channel family. (575 aa) |
| | mps-1 | MiRP K channel accessory Subunit. (257 aa) |
| | best-7 | Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (540 aa) |
| | glc-4 | Glutamate-gated ChLoride channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (500 aa) |
| | che-6 | Cyclic nucleotide-binding domain-containing protein. (655 aa) |
| | stg-1 | STarGazin (Mammalian calcium channel) homolog. (366 aa) |
| | sol-1 | Suppressor of lurcher protein 1; Accessory protein required for glutamate-gated currents. May participate in the gating of non-NMDA (N-methyl-D-aspartate) ionotropic glutamate receptors such as glr-1. (594 aa) |
| | orai-1 | Protein orai; Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, stim-1. Required for Ca(2+) and IP3-dependent contractile activity of sheath cells and the spermatheca. Affects brood size and somatic cell function. Belongs to the Orai family. (297 aa) |
| | C09B9.85 | Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (555 aa) |
| | best-6 | Bestrophin-6. (382 aa) |
| | best-5 | Bestrophin homolog 5; Forms chloride channels. (453 aa) |
| | glr-1 | Glutamate receptor 1; Non-NMDA (N-methyl-D-aspartate) ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of glutamate are mediated by a variety of receptors that are named according to their selective agonists. May contribute to a sensory discrimination between mechanical and chemical stimuli. Plays a role in controlling movement in response to environmental cues such as food availability and mechanosensory stimulation such as the nose touch response. In AIB interneurons, promotes om [...] (962 aa) |
| | best-4 | Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (558 aa) |
| | best-3 | Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (612 aa) |
| | best-1 | Bestrophin homolog 1; Forms chloride channels. (450 aa) |
