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| | C38D9.8 | Uncharacterized protein. (344 aa) |
| | wrm-1 | Armadillo repeat-containing protein wrm-1; Antagonistic role in the Wnt signaling pathway that operates in embryogenesis. When located at the cortex it has been shown to inhibit Wnt signaling during asymmetric cell division but when relocated to the nucleus it shows positive regulation. Has a role in blastomere signaling during endoderm specification. Activates lit-1- dependent kinase activity. Wrm-1/lit-1 complex promotes phosphorylation, down-regulation and subcellular relocation of pop-1. Can substitute for bar-1 indicating functional redundancy. Appears to have a role in centrosome [...] (796 aa) |
| | arle-14 | ARF7EP_C domain-containing protein. (204 aa) |
| | tes-1 | TEStin (Human testis-derived transcript) homolog. (465 aa) |
| | frm-2 | FERM domain-containing protein. (589 aa) |
| | frk-1 | Fer-related kinase 1; Non-receptor tyrosine-protein kinase which plays a role in morphogenesis by regulating the epidermal enclosure of the embryo, independently of its kinase activity. Prevents hyperactivation of the Wnt signaling pathway during endoderm development, probably by preventing hmp-2 nuclear translocation. (390 aa) |
| | rps-16 | 40S ribosomal protein S16. (144 aa) |
| | hmp-1 | Alpha-catenin-like protein hmp-1; Required for cell migration during body enclosure and cell shape changes during body elongation. Required for proper localization of other junctional components, such as pac-1 ; Belongs to the vinculin/alpha-catenin family. (930 aa) |
| | unc-9 | Innexin unc-9; Structural component of the gap junctions. Belongs to the pannexin family. (386 aa) |
| | inx-15 | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (382 aa) |
| | erm-1 | FERM domain-containing protein. (564 aa) |
| | mapk-15 | Mitogen-activated protein kinase 15; Atypical MAPK protein. Regulates primary cilium formation in sensory neurons and the localization of ciliary proteins involved in cilium structure, transport, and signaling. Acts in dopamine (DA) neurons to support synaptic membrane dat-1 availability via activation of rho-1 thereby sustaining normal levels of DA clearance. Plays a role in male mating behavior, probably in part through regulating the localization of the polycystin pkd-2. Functions postembryonically in the URX sensory neurons to constrain URX dendrite growth throughout lifetime, prob [...] (470 aa) |
| | mel-11 | ANK_REP_REGION domain-containing protein. (1124 aa) |
| | pak-1 | Serine/threonine-protein kinase pak-1; Required for hypodermal cell fusion, together with cdc-42 and ced-10, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. Plays a redundant role with max-2 in dorsal axonal guidance in ventral cord commissural motoneurons and in P neuroblast migration. Acts probably downstream of Rho GTPases mig-2 and ced-10 to regulate these 2 processes. Involved in orientating axonal growth of HSN neurons. During gonad morphogenesis and probably in association with pix-1 and git-1, involved in the migration of distal tip ce [...] (572 aa) |
| | ptp-3 | Tyrosine-protein phosphatase Lar-like; Has a role in early neural and epidermal development; neuroblast movements during closure of the gastrulation cleft and epidermal morphogenesis. Vab-1 and ptp-3 may function redundantly within the same sets of neuronal precursors. (2248 aa) |
| | clc-1 | CLaudin-like in Caenorhabditis. (182 aa) |
| | let-502 | Rho-associated protein kinase let-502; Negatively regulates mel-11 to relieve the inhibition of mlc- 4, allowing contraction of the circumferentially oriented microfilaments in epidermal cells and thereby regulating myosin II contractility during spermathecal contraction, cleavage furrow contraction in early embryos, and embryonic elongation and morphogenesis. Required for P-cell migration. May also play a role in oocyte cellularization. (1173 aa) |
| | inx-1 | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (428 aa) |
| | sax-7 | Fibronectin type-III domain-containing protein. (1331 aa) |
| | inx-18 | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (436 aa) |
| | ajm-1 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. (1905 aa) |
| | C25A8.5 | Tyrosine-protein kinase. (416 aa) |
| | dlg-1 | Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family. (967 aa) |
| | eff-1 | Epithelial Fusion Failure. (658 aa) |
| | C26D10.7 | Uncharacterized protein. (596 aa) |
| | syg-2 | Synaptogenesis protein syg-2; Cell adhesion protein. Determines synapse formation. Required for correct localization of syg-1 at synaptic sites. (1230 aa) |
| | pxl-1 | Paxillin homolog 1; Required for myofilament organization of the pharyngeal sarcomeres and for pharyngeal muscle contractions and hence for pharyngeal pumping. Together with lin-8, might be required for myofilament organization in the body wall muscles ; Belongs to the paxillin family. (413 aa) |
| | pat-4 | Integrin-linked protein kinase homolog pat-4; Probable pseudokinase that acts as an adapter protein. Component of an integrin containing attachment complex, which is required for muscle development and maintenance. Involved in the assembly of dense bodies and M lines during body wall muscle development by recruiting several of their components including integrin pat-3, cpna-1, unc-89 and unc- 112 to integrin-mediated attachment sites. Plays a role in distal tip cell (DTC) migration and in oocyte development probably by regulating the actin cytoskeleton. During the formation of neuromus [...] (466 aa) |
| | kin-32 | Inactive tyrosine-protein kinase kin-32; Has apparently no tyrosine kinase activity in vitro when expressed in mammalian cells; Belongs to the protein kinase superfamily. Tyr protein kinase family. FAK subfamily. (867 aa) |
| | rsu-1 | Ras SUppressor homolog. (268 aa) |
| | crb-3 | Drosophila CRumBs homolog. (100 aa) |
| | inx-16 | Innexin-16; Structural component of the gap junctions (By similarity). Required for signals downstream of defecation clock. Belongs to the pannexin family. (372 aa) |
| | inx-17 | Innexin-17; Structural component of the gap junctions. (362 aa) |
| | inx-5 | Innexin-5; Structural component of the gap junctions. Belongs to the pannexin family. (447 aa) |
| | unc-7 | Innexin unc-7; Structural component of the gap junctions (By similarity). Required for coordinated locomotion. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin- 23 and phospholipase plc-3 in ALA neurons, involved in the decrease in pharyngeal pumping during the quiescent state that precedes each larval molt. (546 aa) |
| | ifc-2 | Intermediate filament protein ifc-2; Cytoplasmic intermediate filaments provide mechanical strength to cells. Not essential protein, although its absence leads to mild defects in locomotion. (1248 aa) |
| | M176.9 | Tyrosine-protein kinase. (543 aa) |
| | M116.5 | Uncharacterized protein. (1020 aa) |
| | tns-1 | Tensin homolog; Probable phosphatase which regulates axon regeneration after injury by linking the svh-2 and integrin signaling pathways. (1354 aa) |
| | pix-1 | PIX (PAK (p21-activated kinase) Interacting eXchange factor) homolog. (646 aa) |
| | cif-1 | COP9/Signalosome and eIF3 complex-shared subunit 1; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation (Potential). Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essen [...] (390 aa) |
| | mua-3 | Transmembrane cell adhesion receptor mua-3; Involved in cell adhesion and required for organ positioning and attachment. At the hypodermal surface, required for attachment of the hypdermermis to the basal cuticle in postembryonic development, possibly through intermediate filaments of the cytoskeleton. (3767 aa) |
| | toca-2 | Transducer of Cdc42-dependent actin assembly protein 2 homolog; Plays a role in protein trafficking, actin organization and embryonic morphogenesis. Potentially acts as cdc-42 effector. May play a role in egg laying. Together with toca-1, is required for protein trafficking regulating yolk protein clathrin-mediated endocytosis by oocytes during oogenesis and retrograde recycling and the sorting of recycling endosome cargo proteins such as mig-14. Also, together with toca-2, controls the distribution of actin at cell junctions. Belongs to the FNBP1 family. (610 aa) |
| | mup-4 | Transmembrane matrix receptor MUP-4; Required for junctional attachments between hypodermis and muscle, and between the apical epithelial surface and the cuticular matrix. Essential for enclosure of the embryo by the hypodermis, hypodermal integrity, embryo elongation, and maintenance of hypodermal morphology in fully elongated embryos. (2104 aa) |
| | hmp-2 | Beta-catenin-like protein hmp-2; Required for cell migration during body enclosure and cell shape changes during body elongation. Plays a role in recruitment of the cadherin protein hmr-1 to adherens junctions. (704 aa) |
| | apr-1 | Adenomatous polyposis coli protein-related protein 1; Has a role in endoderm cell specification and pharyngeal development. Required for the migration of epithelial cells, organization of the anterior seam cells and ceh-13 expression during embryo morphogenesis. Prevents hyperactivation of the Wnt signaling pathway during endoderm development, probably by preventing hmp-2 nuclear translocation. During larval development, apr-1 is required for expression of lin-39 in P3-8.p. Shown to negatively regulate Wnt signaling in vulval precursor cells. Has a role in cell division by establishing [...] (1188 aa) |
| | unc-1 | Protein unc-1. (289 aa) |
| | ltd-1 | LIM zinc-binding domain-containing protein. (723 aa) |
| | inx-7 | Innexin-7; Structural component of the gap junctions. Belongs to the pannexin family. (556 aa) |
| | magi-1 | MAGI (Membrane Associated Guanylate kinase Inverted) homolog. (1054 aa) |
| | let-805 | Myotactin form B. (4450 aa) |
| | F59C12.3 | Uncharacterized protein. (519 aa) |
| | cdh-9 | CaDHerin family. (623 aa) |
| | sta-2 | Signal transducer and activator of transcription b; Carries out a dual function: signal transduction and activation of transcription (By similarity). By regulating the up- regulation in the epidermis of antimicrobial peptides nlp-29, plays a role in resistance to fungal infection and in the response to physical wounding and phorbol ester PMA treatment. Belongs to the transcription factor STAT family. (567 aa) |
| | F55F8.7 | Protein-tyrosine-phosphatase. (491 aa) |
| | par-3 | Partitioning defective protein 3; In cooperation with pkc-3, required for establishing cell polarity and regulating spindle orientation in the early embryo. Localization is crucial for recruiting par-6 and pkc-3 to the peripheral apical cortex and restricting par-2 to basolateral surfaces. Necessary for apicobasal and anterior-posterior asymmetries associated with cell adhesion and gastrulation during the first few cycles of embryogenesis, and also for epithelial cell polarity in the distal spermatheca. Regulates the asymmetric localization of csnk-1, ppk-1 and gpr-1/2 during the first [...] (1533 aa) |
| | F53B3.5 | Uncharacterized protein. (312 aa) |
| | nmy-1 | Non-muscle MYosin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1963 aa) |
| | vha-17 | V-type proton ATPase subunit e; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (86 aa) |
| | lon-1 | Protein lon-1; Regulates body size morphogenesis, but does not affect male tail development; Belongs to the CRISP family. (312 aa) |
| | kin-20 | Casein kinase I isoform delta; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity). Is a developmental timer that specifies temporal cell fate selection; acts to control the temporal identity of hypodermal seam cells. Required during late-larval development to prevent adult fates, particularly cell cycle exit and fusion, from being expressed too early. (497 aa) |
| | gei-1 | START domain-containing protein. (1510 aa) |
| | magu-4 | MAGUK family. (1084 aa) |
| | magu-2 | MAGUK family; Belongs to the MAGUK family. (830 aa) |
| | zyx-1 | Zyxin; Functions as both a mechanical stabilizer (via LIM domains) of focal adhesions and as a sensor component for muscle cell damage (via N-terminus). Regulates, stabilizes and maintains posterior lateral mechanosensory (PLM) synaptic branch extension and new synapse formation and growth during larval development. (647 aa) |
| | nfm-1 | FERM domain-containing protein. (709 aa) |
| | sdz-16 | SKN-1 Dependent Zygotic transcript. (344 aa) |
| | picc-1 | PAC-1 interacting and coiled-coil domain-containing protein 1; Linker protein which helps to recruit the Rho GTPase- activating protein, pac-1, to adherens junctions. (535 aa) |
| | F26F4.5 | Calponin-homology (CH) domain-containing protein. (465 aa) |
| | let-413 | Protein lap1; Critical role in assembling adherens junctions; adapter protein involved in polarizing protein trafficking in epithelial cells. Necessary to maintain, not establish, the entire terminal web (organelle-depleted, intermediate filament-rich layer of cytoplasm that underlies the apical microvilli of polarized epithelial cells) or brush border assembly at the apical surface gut cells. Required for correct localization of ifb-2 intermediate filaments in the terminal web. Required for dlg-1 lateral localization. With dlg-1, cooperatively regulates ajm-1 localization to apical ju [...] (699 aa) |
| | che-7 | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (563 aa) |
| | F25H5.7 | Protein-tyrosine-phosphatase. (490 aa) |
| | F23C8.7 | Tyrosine-protein kinase. (417 aa) |
| | inx-3 | Innexin-3; Structural component of the gap junctions. Belongs to the pannexin family. (420 aa) |
| | F22E5.17 | FBA_2 domain-containing protein. (297 aa) |
| | kin-14 | Tyrosine-protein kinase. (418 aa) |
| | F20H11.4 | Protein-tyrosine-phosphatase. (446 aa) |
| | nlr-1 | Neurexin Like receptor. (1180 aa) |
| | F16B12.5 | annotation not available (227 aa) |
| | git-1 | GIT1 (Mammalian G protein-coupled receptor kinase InTeractor 1) homolog. (670 aa) |
| | mec-2 | Mechanosensory protein 2; Positively regulates the activity of the putative mechanosensory transduction channel. May link the mechanosensory channel and the microtubule cytoskeleton of the touch receptor neurons. Required for the function of a set of six touch receptor neurons. (1239 aa) |
| | unc-97 | LIM domain-containing protein unc-97; Component of an integrin containing attachment complex, which is required for muscle development and maintenance. Probably function in adherens junction. Affects the structural integrity of the integrin containing muscle adherens junctions and contributes to the mechanosensory functions of touch neurons. (348 aa) |
| | eat-5 | Innexin eat-5; Structural component of the gap junctions (By similarity). Required for synchronized pharyngeal muscle contractions. Belongs to the pannexin family. (423 aa) |
| | srgp-1 | Rho-GAP domain-containing protein. (1059 aa) |
| | toca-1 | Transducer of Cdc42-dependent actin assembly protein 1 homolog; Plays a role in protein trafficking, actin organization and embryonic morphogenesis. Potentially acts as cdc-42 effector. May play a role in hypodermal P-cell nuclear positioning. Together with toca-2, is required for protein trafficking regulating yolk protein clathrin- mediated endocytosis by oocytes during oogenesis and retrograde recycling and the sorting of recycling endosome cargo proteins such as mig-14. Also, together with toca-2, controls the distribution of actin at cell junctions. (592 aa) |
| | inx-2 | Innexin-2; Structural component of the gap junctions. Belongs to the pannexin family. (419 aa) |
| | pin-2 | LIM domain-containing protein pin-2. (330 aa) |
| | inx-14 | Innexin-14; Structural component of the gap junctions. (434 aa) |
| | D1069.1 | Uncharacterized protein. (198 aa) |
| | C55C3.4 | Tyrosine-protein kinase. (431 aa) |
| | bar-1 | Beta-catenin/armadillo-related protein 1; Participates in the Wnt signaling pathway which affects cell fate and may regulate the stem cell divisions of seam cells during larval development. Functions as a transcriptional activator but is dependent on the interaction with pop-1. Involved in maintaining lin-39 Hox expression and regulating glr-1 abundance at the synapses. Required for mab-5 expression during Q neuroblast migration and for oxidative stress-induced daf-16 signaling. Has roles in egg laying, vulva precursor cell fate determination, Q neuroblast migration, posterior ectoderm [...] (811 aa) |
| | unc-112 | Protein unc-112; Component of an integrin containing attachment complex, which is required for muscle development and maintenance. Probable regulator of cell-extracellular matrix adhesion. Required during initial muscle assembly to form dense bodies and M-lines. (720 aa) |
| | aff-1 | Cell fusion protein aff-1; Required for cell fusion events during development including the fusion of anchor cells (AC), vulval A and vulval D rings, and late epidermal seam cells. Required for amphid sheath cell fusion induced by entry into dauer stage. (589 aa) |
| | inx-6 | Innexin-6; Structural component of the gap junctions. Belongs to the pannexin family. (389 aa) |
| | inx-9 | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (382 aa) |
| | inx-8 | Innexin-8; Structural component of the gap junctions. Belongs to the pannexin family. (382 aa) |
| | inx-12 | Innexin-12; Structural component of the gap junctions (By similarity). Plays a role in oocyte directional transit in the spermatheca during ovulation by facilitating the directional propagation of the calcium signal in the spermatheca. Plays a role in male tail tip morphogenesis ; Belongs to the pannexin family. (408 aa) |
| | spv-1 | Spermathecal Physiology Variant. (966 aa) |
| | ZK622.1 | Tyrosine-protein kinase. (419 aa) |
| | vab-10 | GAR domain-containing protein. (5059 aa) |
| | let-23 | Receptor tyrosine-protein kinase let-23; Tyrosine-protein kinase receptor which, upon binding ligand lin-3, activates 2 signaling cascades: the let-60/Ras and MAP kinase signaling pathway and the let-60-independent phospholipase C-mediated Ca(2+) signaling pathway. Each pathway regulates distinct functions. By activating let-60/Ras, regulates larval development, induction of vulva cell precursors during vulva development, male spicule formation and posterior development of the epidermis. Probably by activating phospholipase plc-3 and inositol 1,4,5-trisphosphate receptor itr-1 signalin [...] (1335 aa) |
| | pat-3 | Integrin beta pat-3; Integrin alpha ina-1/beta pat-3 is a receptor for laminin. Integrin alpha pat-2/beta pat-3 recognizes the sequence R-G-D in its ligands (Probable). Plays a role in cell migration, morphogenesis and probably in cell-cell interactions. During gonad morphogenesis, involved in distal tip cell (DTC)-mediated guidance of gonad elongation, in maintaining their sharp tapering morphology and in their migration. Component of an integrin containing attachment complex, which is required for muscle development and maintenance. Involved in the assembly of dense bodies and M line [...] (809 aa) |
| | deb-1 | Vinculin; Involved in cell adhesion. May be involved in the attachment of the actin-based microfilaments to the plasma membrane. Involved in ovulation. (1090 aa) |
| | inx-13 | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (385 aa) |
| | Y82E9BR.3 | ATP synthase lipid-binding protein, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism [...] (116 aa) |
| | Y82E9BR.19 | F-box domain-containing protein. (417 aa) |
| | cua-1 | Copper transporting ATPase. (1238 aa) |
| | tln-1 | Talin. (2553 aa) |
| | oig-5 | Ig-like domain-containing protein. (164 aa) |
| | eps-8 | SH3 domain-containing protein. (942 aa) |
| | tag-273 | LIM zinc-binding domain-containing protein. (891 aa) |
| | magu-1 | MAGUK family. (567 aa) |
| | lin-7 | Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (209 aa) |
| | Y52B11A.11 | Uncharacterized protein. (341 aa) |
| | csk-1 | Tyrosine-protein kinase csk-1; Non-receptor tyrosine-protein kinase which plays a role in pharynx function by regulating pumping and the orientation of pharyngeal muscle fibers, independently of src-1 and src-2. May phosphorylate and thereby negatively regulate src-1 and src-2 activities. (624 aa) |
| | inx-22 | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (462 aa) |
| | inx-21 | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (481 aa) |
| | sorb-1 | Sorbin and SH3 domain-containing protein 1 homolog; Required for organization of sarcomeres in body wall muscles and for maintaining normal mitochondrial position in myocytes. (1005 aa) |
| | cdap-2 | CD2AP homolog. (551 aa) |
| | Y44A6C.2 | Uncharacterized protein. (354 aa) |
| | Y43C5B.2 | Tyrosine-protein kinase. (245 aa) |
| | Y1A5A.1 | Uncharacterized protein. (192 aa) |
| | Y119C1B.3 | Uncharacterized protein. (450 aa) |
| | zoo-1 | ZO-1 (Zonula Occludens tight junctional protein) Ortholog. (1172 aa) |
| | exc-4 | Chloride intracellular channel exc-4; May insert into membranes and form chloride ion channels. Involved in the formation of the excretory canal. Required to prevent cystic lumenal expansions in the excretory cell. Not required for formation of the initial tube, but is required for regulating the size of the tube lumen as it grows. (290 aa) |
| | jac-1 | Juxtamembrane domain-associated catenin; May act as a positive modulator of hmr-1 function during epidermal morphogenesis. Required for proper localization of other junctional components, such as pac-1 ; Belongs to the beta-catenin family. (1256 aa) |
| | mua-6 | Intermediate filament protein ifa-2; Cytoplasmic intermediate filaments provide mechanical strength to cells. Essential protein, involved in attachment structures in epidermal cells that connect muscles to the external cuticle. Probably acts by forming hypodermal hemidesmosome complexes that help mediate muscle-cuticle force transduction. Although expressed during embryogenesis, it is not required for embryonic development of muscle- cuticle linkages nor for the localization of other proteins to the hemidesmosomes in embryos. (581 aa) |
| | inx-11 | Innexin-11; Structural component of the gap junctions. Belongs to the pannexin family. (529 aa) |
| | C35E7.10 | Tyrosine-protein kinase. (430 aa) |
| | afd-1 | PDZ domain-containing protein. (1660 aa) |
| | itx-1 | InTestinal NeureXin-like. (1645 aa) |
| | hmr-1 | Cadherin-related hmr-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Required for adherens junction assembly and connecting adherens junctions to the cytoskeleton. Isoform b is involved in axonal guidance in a subset of motor neurons. (2920 aa) |
| | T28F4.3 | Protein-tyrosine-phosphatase. (490 aa) |
| | T28D6.7 | START domain-containing protein. (322 aa) |
| | par-6 | Partitioning defective protein 6; Necessary for apicobasal and anterior-posterior asymmetries associated with cell adhesion and gastrulation during the first few cell cycles of embryogenesis. Required for localizing/ maintaining par-3 at the cell periphery. Regulates mes-1 expression and/or localization pattern during early embryogenesis. Acts together with par-3 and pkc-3 in maintaining epithelial cell polarity in the distal spermatheca. Plays a role in endosome and Golgi body positioning. Belongs to the PAR6 family. (309 aa) |
| | act-5 | ACTin. (375 aa) |
| | nas-5 | Zinc metalloproteinase nas-5; Metalloprotease. (360 aa) |
| | inx-20 | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (483 aa) |
| | vab-19 | ANK_REP_REGION domain-containing protein. (1040 aa) |
| | vab-9 | Cell junction protein VAB-9. (211 aa) |
| | T21G5.1 | Tyrosine-protein kinase. (514 aa) |
| | pat-6 | Paralyzed arrest at two-fold protein 6; Involved in the regulation of cell adhesion and cytoskeleton organization. Component of an integrin containing attachment complex, which is required for muscle development and maintenance. During embryonic development, required to recruit cpna-1, unc-89 and myofilaments to newly forming integrin attachments composed of integrins pat-2/pat-3, pat-4 and unc-112. Also required to reposition the integrin-based attachments so that they form the highly ordered array of dense body and M-line attachments that are characteristic of mature muscle cells. Du [...] (375 aa) |
| | inx-10 | Innexin-10; Structural component of the gap junctions. Belongs to the pannexin family. (559 aa) |
| | pat-12 | annotation not available (1030 aa) |
| | inx-19 | Innexin-19; Structural component of the gap junctions that specifically coordinates left-right asymmetry in the developing nervous system. Acts by forming gap junction network linking embryonic neurons and providing electrical coupling between cells, leading to promote or inhibit AWC signaling. Required for the left and right AWC olfactory neurons to establish asymmetric patterns of gene expression during embryogenesis. Acts autonomously. (454 aa) |
| | alp-1 | ALP/Enigma encoding. (1424 aa) |
| | kin-26 | Tyrosine-protein kinase. (433 aa) |
| | T06C10.3 | Tyrosine-protein kinase. (557 aa) |
