STRINGSTRING
C17E4.1 C17E4.1 mrpl-9 mrpl-9 mrpl-47 mrpl-47 mrpl-41 mrpl-41 B0495.9 B0495.9 mrps-30 mrps-30 fog-3 fog-3 sdha-1 sdha-1 pdhb-1 pdhb-1 C04F5.8 C04F5.8 tin-9.1 tin-9.1 atp-5 atp-5 C08F8.2 C08F8.2 nuo-1 nuo-1 mrps-22 mrps-22 C14B9.10 C14B9.10 tomm-40 tomm-40 immp-1 immp-1 C25H3.9 C25H3.9 mrps-18C mrps-18C ech-1.1 ech-1.1 mrpl-32 mrpl-32 dlat-2 dlat-2 C33A12.1 C33A12.1 sdha-2 sdha-2 C34B2.8 C34B2.8 C34C12.8 C34C12.8 gop-3 gop-3 atp-2 atp-2 C43E11.12 C43E11.12 C47G2.3 C47G2.3 C53B4.4 C53B4.4 asg-2 asg-2 cyc-1 cyc-1 C56A3.6 C56A3.6 mrpl-18 mrpl-18 timm-17B.2 timm-17B.2 tin-13 tin-13 timm-17B.1 timm-17B.1 pink-1 pink-1 ard-1 ard-1 asb-2 asb-2 dnj-9 dnj-9 mrpl-13 mrpl-13 timm-23 timm-23 romo-1 romo-1 emre-1 emre-1 dlat-1 dlat-1 tomm-20 tomm-20 cox-5B cox-5B atp-3 atp-3 bckd-1B bckd-1B mrps-21 mrps-21 F31D4.9 F31D4.9 eef-1A.1 eef-1A.1 F32B5.1 F32B5.1 mccc-1 mccc-1 hpo-18 hpo-18 sdhd-1 sdhd-1 F33D11.2 F33D11.2 mrps-24 mrps-24 asb-1 asb-1 F36D4.6 F36D4.6 mtx-1 mtx-1 F42A8.1 F42A8.1 sdhb-1 sdhb-1 F42G8.10 F42G8.10 isp-1 isp-1 mrpl-21 mrpl-21 argk-1 argk-1 F44G4.2 F44G4.2 F45G2.8 F45G2.8 F45H10.2 F45H10.2 F45H10.3 F45H10.3 ttr-57 ttr-57 tsen-54 tsen-54 F53F4.10 F53F4.10 F54A3.5 F54A3.5 mrpl-40 mrpl-40 cox-6A cox-6A F56B3.11 F56B3.11 oxy-5 oxy-5 F58F12.1 F58F12.1 mrpl-24 mrpl-24 atp-1 atp-1 mcu-1 mcu-1 moma-1 moma-1 vms-1 vms-1 asg-1 asg-1 pdr-1 pdr-1 gas-1 gas-1 cid-1 cid-1 K11D2.5 K11D2.5 K12D9.1 K12D9.1 mrpl-35 mrpl-35 ymel-1 ymel-1 chch-3 chch-3 mrps-34 mrps-34 nduo-1 nduo-1 atp-6 atp-6 nduo-2 nduo-2 ctb-1 ctb-1 nduo-4 nduo-4 ctc-1 ctc-1 nduo-3 nduo-3 nduo-5 nduo-5 ndfl-4 ndfl-4 R02F2.9 R02F2.9 eef-1A.2 eef-1A.2 R04F11.5 R04F11.5 R05D3.6 R05D3.6 R07E4.3 R07E4.3 R08E5.1 R08E5.1 R08E5.3 R08E5.3 R08F11.4 R08F11.4 R11D1.13 R11D1.13 mrpl-49 mrpl-49 mrps-6 mrps-6 T02H6.11 T02H6.11 mrps-12 mrps-12 mrpl-16 mrpl-16 T04B2.7 T04B2.7 mev-1 mev-1 ech-1.2 ech-1.2 mrpl-23 mrpl-23 ucr-2.2 ucr-2.2 nuo-2 nuo-2 mrpl-51 mrpl-51 T14B4.1 T14B4.1 mrps-18.C mrps-18.C immt-1 immt-1 dnj-21 dnj-21 T20H4.5 T20H4.5 mrpl-50 mrpl-50 scpl-4 scpl-4 smz-2 smz-2 T22D1.3 T22D1.3 mrpl-4 mrpl-4 ucr-2.3 ucr-2.3 phb-2 phb-2 mrpl-28 mrpl-28 nduf-2.2 nduf-2.2 T27E9.2 T27E9.2 asic-2 asic-2 ucr-2.1 ucr-2.1 nuo-6 nuo-6 mrpl-30 mrpl-30 W04C9.2 W04C9.2 W04D2.4 W04D2.4 mrps-11 mrps-11 immt-2 immt-2 cox-4 cox-4 W10C8.5 W10C8.5 nduf-7 nduf-7 rpom-1 rpom-1 Y108F1.1 Y108F1.1 mrpl-19 mrpl-19 cox-5A cox-5A mrps-10 mrps-10 phb-1 phb-1 ppgn-1 ppgn-1 ddp-1 ddp-1 hlh-33 hlh-33 mrps-35 mrps-35 bckd-1A bckd-1A Y43F4A.4 Y43F4A.4 mrps-28 mrps-28 acdh-11 acdh-11 nuo-5 nuo-5 mrpl-39 mrpl-39 Y47C4A.1 Y47C4A.1 spg-7 spg-7 mrpl-37 mrpl-37 Y51H1A.3 Y51H1A.3 Y53G8AL.2 Y53G8AL.2 mrpl-17 mrpl-17 nduf-5 nduf-5 mrps-25 mrps-25 Y55F3AM.13 Y55F3AM.13 immp-2 immp-2 Y55F3BL.4 Y55F3BL.4 polg-1 polg-1 coq-3 coq-3 nuo-3 nuo-3 mrps-7 mrps-7 Y63D3A.7 Y63D3A.7 tin-10 tin-10 micu-1 micu-1 Y67H2A.7 Y67H2A.7 mppa-1 mppa-1 Y82E9BR.3 Y82E9BR.3 Y92H12BR.3 Y92H12BR.3 mrpl-15 mrpl-15 Y94A7B.11 Y94A7B.11 ZC262.5 ZC262.5 mrps-18A mrps-18A mrpl-42 mrpl-42 mppb-1 mppb-1 coa-6 coa-6 mtx-2 mtx-2 mrps-23 mrps-23 ZK287.1 ZK287.1 ZK470.1 ZK470.1 tomm-7 tomm-7 ZK686.2 ZK686.2 ZK686.5 ZK686.5 ZK809.3 ZK809.3 lpd-5 lpd-5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C17E4.1Uncharacterized protein. (425 aa)
mrpl-9RIBOSOMAL_L9 domain-containing protein. (276 aa)
mrpl-47Mitochondrial Ribosomal Protein, Large. (234 aa)
mrpl-4139S ribosomal protein L41, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL41 family. (180 aa)
B0495.9Uncharacterized protein B0495.9. (267 aa)
mrps-30Mitochondrial Ribosomal Protein, Small. (523 aa)
fog-3Anti_prolifrtn domain-containing protein. (263 aa)
sdha-1Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (646 aa)
pdhb-1Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (352 aa)
C04F5.8Uncharacterized protein. (342 aa)
tin-9.1Mitochondrial import inner membrane translocase subunit Tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (Probable). Belongs to the small Tim family. (78 aa)
atp-5ATP synthase subunit. (191 aa)
C08F8.2ATP-dependent RNA helicase SUV3 homolog, mitochondrial; ATPase and DNA/RNA helicase able to unwind DNA/DNA, DNA/RNA and RNA/RNA duplexes in the 5'-3' direction. (719 aa)
nuo-1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (479 aa)
mrps-22Mitochondrial Ribosomal Protein, Small. (418 aa)
C14B9.10Uncharacterized protein. (60 aa)
tomm-40Mitochondrial import receptor subunit TOM40 homolog; Channel-forming protein essential for import of protein precursors into mitochondria. Specifically required for nnt-1 accumulation in the mitochondria and may be involved in the secretion of daf-28/insulin from the mitochondria. Required for embryonic and larval development. (301 aa)
immp-1Peptidase_S24 domain-containing protein. (132 aa)
C25H3.9Uncharacterized protein. (186 aa)
mrps-18CPutative 39S ribosomal protein L3, mitochondrial. (403 aa)
ech-1.1Enoyl-CoA Hydratase. (755 aa)
mrpl-32Probable 39S ribosomal protein L32, mitochondrial. (183 aa)
dlat-22-oxoacid_dh domain-containing protein. (337 aa)
C33A12.1Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (150 aa)
sdha-2Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (640 aa)
C34B2.8Uncharacterized protein. (171 aa)
C34C12.8GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity). (237 aa)
gop-3SAM50-like protein gop-3; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family. (434 aa)
atp-2ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] (538 aa)
C43E11.12TFIIIC_sub6 domain-containing protein. (184 aa)
C47G2.3Mitochondrial import inner membrane translocase subunit tim-22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). (213 aa)
C53B4.4Uncharacterized protein. (1362 aa)
asg-2Probable ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism [...] (131 aa)
cyc-1Cytochrome c domain-containing protein. (285 aa)
C56A3.6Uncharacterized protein. (477 aa)
mrpl-1839S ribosomal protein L18, mitochondrial; Belongs to the universal ribosomal protein uL18 family. (170 aa)
timm-17B.2Translocase, Inner Mitochondrial Membrane. (140 aa)
tin-13Mitochondrial import inner membrane translocase subunit tim-13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The tim-8- tim-13 complex mediates the import of some pro [...] (108 aa)
timm-17B.1Probable mitochondrial import inner membrane translocase subunit tim-17B.1; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane; Belongs to the Tim17/Tim22/Tim23 family. (181 aa)
pink-1Serine/threonine-protein kinase pink-1, mitochondrial; Protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins (By similarity). Plays a role in mitophagy. (641 aa)
ard-1Alcohol/Ribitol Dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (258 aa)
asb-2ATP Synthase B homolog. (305 aa)
dnj-9J domain-containing protein. (564 aa)
mrpl-13Mitochondrial Ribosomal Protein, Large. (205 aa)
timm-23Translocase, Inner Mitochondrial Membrane. (242 aa)
romo-1(Reactive Oxygen species MOdulator) homolog. (82 aa)
emre-1Essential MCU regulator, mitochondrial; Essential regulatory subunit of the mitochondrial calcium uniporter (mcu-1) channel, a protein that mediates calcium uptake into mitochondria; Belongs to the SMDT1/EMRE family. (90 aa)
dlat-1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (507 aa)
tomm-20Mitochondrial import receptor subunit TOM20 homolog; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins (By similarity). Together with tomm-22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore. (188 aa)
cox-5BCytochrome OXidase assembly protein. (132 aa)
atp-3ATP synthase subunit. (228 aa)
bckd-1BTransket_pyr domain-containing protein. (366 aa)
mrps-21Mitochondrial Ribosomal Protein, Small. (113 aa)
F31D4.9Uncharacterized protein. (70 aa)
eef-1A.1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (463 aa)
F32B5.1Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (427 aa)
mccc-1MethylCrotonoyl-Coenzyme A Carboxylase (Alpha). (671 aa)
hpo-18Uncharacterized protein. (54 aa)
sdhd-1Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (145 aa)
F33D11.2Uncharacterized protein. (375 aa)
mrps-2428S ribosomal protein S24, mitochondrial; Belongs to the universal ribosomal protein uS3 family. (164 aa)
asb-1ATP Synthase B homolog. (301 aa)
F36D4.6Uncharacterized protein. (91 aa)
mtx-1Metaxin-1 homolog; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family. (312 aa)
F42A8.1Uncharacterized protein F42A8.1. (370 aa)
sdhb-1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (298 aa)
F42G8.10Uncharacterized protein. (181 aa)
isp-1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (276 aa)
mrpl-21Mitochondrial Ribosomal Protein, Large. (171 aa)
argk-1ARGinine Kinase; Belongs to the ATP:guanido phosphotransferase family. (372 aa)
F44G4.2Probable NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (160 aa)
F45G2.8Mitochondrial import inner membrane translocase subunit tim-16; Regulates ATP-dependent protein translocation into the mitochondrial matrix; Belongs to the TIM16/PAM16 family. (136 aa)
F45H10.2Uncharacterized protein. (90 aa)
F45H10.3Uncharacterized protein. (168 aa)
ttr-57TransThyretin-Related family domain. (89 aa)
tsen-54tRNA_int_end_N2 domain-containing protein. (335 aa)
F53F4.10Probable NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (239 aa)
F54A3.5MICOS complex subunit Mic10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (105 aa)
mrpl-40Mitochondrial Ribosomal Protein, Large. (189 aa)
cox-6ACytochrome c oxidase subunit 6A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (128 aa)
F56B3.11Uncharacterized protein. (213 aa)
oxy-5Uncharacterized protein. (162 aa)
F58F12.1ATP synthase subunit delta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] (163 aa)
mrpl-24Probable 39S ribosomal protein L24, mitochondrial. (278 aa)
atp-1ATP synthase subunit alpha, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...] (538 aa)
mcu-1Calcium uniporter protein, mitochondrial; Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore- forming and calcium-conducting subunit (By similarity). Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways (By similarity). Required for rapid mitochondrial calcium uptake and mitochondrial reactive oxygen species (mtROS) production after wounding. (333 aa)
moma-1MICOS complex subunit MIC27; Sustains mitochondrial morphology probably through maintaining cristae morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity). (201 aa)
vms-1Protein vms-1; Involved in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. Component of an evolutionarily conserved system for ubiquitin-mediated mitochondria-associated protein degradation (MAD) (By similarity). Dispensable for viability and growth but is required for protection against oxidative stress and for wild- type life span. (618 aa)
asg-1Probable ATP synthase subunit g 1, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism [...] (131 aa)
pdr-1E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (386 aa)
gas-1Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (482 aa)
cid-14Fe-4S ferredoxin-type domain-containing protein. (1425 aa)
K11D2.5Uncharacterized protein. (348 aa)
K12D9.1Methyltranfer_dom domain-containing protein. (354 aa)
mrpl-35Probable 39S ribosomal protein L35, mitochondrial. (158 aa)
ymel-1ATP-dependent zinc metalloprotease YME1 homolog; ATP-dependent metalloprotease that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region (By similarity). Plays an important role in regulating mitochondrial morphology and function (By similarity); In the C-terminal section; belongs to the peptidase M41 family. (723 aa)
chch-3MICOS complex subunit MIC19; Plays a role in maintaining mitochondrial morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity). Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic19 subfamily. (169 aa)
mrps-34Mitochondrial Ribosomal Protein, Small. (228 aa)
nduo-1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (291 aa)
atp-6ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (199 aa)
nduo-2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (282 aa)
ctb-1Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c (By similarity). Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (370 aa)
nduo-4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (409 aa)
ctc-1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (525 aa)
nduo-3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (111 aa)
nduo-5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (527 aa)
ndfl-4NADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (77 aa)
R02F2.9RF_PROK_I domain-containing protein. (165 aa)
eef-1A.2Elongation factor 1-alpha. (463 aa)
R04F11.5Uncharacterized protein. (185 aa)
R05D3.6Putative ATP synthase subunit epsilon, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechan [...] (54 aa)
R07E4.3Uncharacterized protein. (90 aa)
R08E5.1Methyltranfer_dom domain-containing protein. (317 aa)
R08E5.3Methyltranfer_dom domain-containing protein. (365 aa)
R08F11.4Methyltranfer_dom domain-containing protein. (354 aa)
R11D1.13Uncharacterized protein. (95 aa)
mrpl-49Probable 39S ribosomal protein L49, mitochondrial. (187 aa)
mrps-6Mitochondrial Ribosomal Protein, Small. (162 aa)
T02H6.11Uncharacterized protein. (130 aa)
mrps-12Mitochondrial Ribosomal Protein, Small; Belongs to the universal ribosomal protein uS12 family. (157 aa)
mrpl-16Ribosomal_L16 domain-containing protein. (240 aa)
T04B2.7Uncharacterized protein. (367 aa)
mev-1Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). Mediates resistance to enteropathogenic E.coli infection. Belongs to the cytochrome b560 family. (182 aa)
ech-1.2Enoyl-CoA Hydratase. (781 aa)
mrpl-23Probable 39S ribosomal protein L23, mitochondrial; Belongs to the universal ribosomal protein uL23 family. (159 aa)
ucr-2.2Ubiquinol-Cytochrome c oxidoReductase complex. (422 aa)
nuo-2Complex1_30kDa domain-containing protein; Belongs to the complex I 30 kDa subunit family. (268 aa)
mrpl-5139S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL51 family. (199 aa)
T14B4.1SpoU_methylase domain-containing protein. (1225 aa)
mrps-18.CMitochondrial Ribosomal Protein, Small. (139 aa)
immt-1MICOS complex subunit MIC60-1; Sustains mitochondrial morphology probably through maintaining cristae morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity). (679 aa)
dnj-21Mitochondrial import inner membrane translocase subunit TIM14; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity). (112 aa)
T20H4.5Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (212 aa)
mrpl-50Mitochondrial Ribosomal Protein, Large. (285 aa)
scpl-4Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane; Belongs to the TIM50 family. (452 aa)
smz-2Sperm Meiosis PDZ domain containing proteins. (274 aa)
T22D1.3Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (534 aa)
mrpl-4Mitochondrial Ribosomal Protein, Large. (299 aa)
ucr-2.3Peptidase_M16 domain-containing protein. (427 aa)
phb-2Mitochondrial prohibitin complex protein 2; PHB proteins are essential during embryonic development and are required for somatic and germline differentiation in the larval gonad. A deficiency in PHB proteins results in altered mitochondrial biogenesis in body wall muscle cells. (294 aa)
mrpl-28Mitochondrial Ribosomal Protein, Large. (310 aa)
nduf-2.2Complex1_49kDa domain-containing protein; Belongs to the complex I 49 kDa subunit family. (474 aa)
T27E9.2Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (75 aa)
asic-2Degenerin-like protein asic-2. (545 aa)
ucr-2.1Ubiquinol-Cytochrome c oxidoReductase complex. (424 aa)
nuo-6NADH Ubiquinone Oxidoreductase. (172 aa)
mrpl-30Mitochondrial Ribosomal Protein, Large. (197 aa)
W04C9.2MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (102 aa)
W04D2.4C2H2-type domain-containing protein. (624 aa)
mrps-11Mitochondrial Ribosomal Protein, Small. (208 aa)
immt-2MICOS complex subunit MIC60-2; Sustains mitochondrial morphology probably through maintaining cristae morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity). (654 aa)
cox-4Cytochrome OXidase assembly protein. (175 aa)
W10C8.5Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (399 aa)
nduf-7Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (199 aa)
rpom-1DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1156 aa)
Y108F1.1annotation not available (238 aa)
mrpl-19Probable 39S ribosomal protein L19, mitochondrial. (288 aa)
cox-5ACytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (174 aa)
mrps-10Probable 28S ribosomal protein S10, mitochondrial; Ribosomal protein required for normal mitochondrial function and normal larval development. Thought to have a role in insulin/IGF signaling. (156 aa)
phb-1Mitochondrial prohibitin complex protein 1; PHB proteins are essential during embryonic development and are required for somatic and germline differentiation in the larval gonad. A deficiency in PHB proteins results in altered mitochondrial biogenesis in body wall muscle cells. (275 aa)
ppgn-1AAA domain-containing protein. (747 aa)
ddp-1Mitochondrial import inner membrane translocase subunit Tim8; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane (By similarity). Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane (By similarity). Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity). The ddp-1/t [...] (83 aa)
hlh-33BHLH domain-containing protein. (407 aa)
mrps-35MRP-S28 domain-containing protein. (365 aa)
bckd-1A2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). Required for the production of the monomethyl branched-chain fatty acids (mmBCFAs) isopentadecanoate (C15iso) and isoheptadecanoate (C17iso). (432 aa)
Y43F4A.42-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (105 aa)
mrps-28Mitochondrial Ribosomal Protein, Small. (172 aa)
acdh-11Acyl-CoA dehydrogenase family member 11; Promotes adaption to elevated temperatures by regulating expression of the lipid desaturase, fat-7. Binds selectively and with high affinity to fatty acids with chain lengths from C10 to C12 and prevents them from activating fat-7 expression mediated by the nuclear hormone receptor nhr-49, leading to low levels of membrane lipid desaturation and membrane fluidity for adaption to heat. (617 aa)
nuo-5NADH Ubiquinone Oxidoreductase; Belongs to the complex I 75 kDa subunit family. (729 aa)
mrpl-39Mitochondrial Ribosomal Protein, Large. (295 aa)
Y47C4A.1Uncharacterized protein. (408 aa)
spg-7AFG3-like protein spg-7; Acts as a component of the m-AAA protease complex which is an ATP-dependent metalloprotease mediating degradation of non-assembled mitochondrial inner membrane proteins (By similarity). The complex is necessary for the assembly of mitochondrial respiratory chain and ATPase complexes (By similarity). Functions both in post-translational assembly and in the turnover of mistranslated or misfolded polypeptides. Plays a role in male tail tip morphogenesis. In the C-terminal section; belongs to the peptidase M41 family. (782 aa)
mrpl-37Mitochondrial Ribosomal Protein, Large. (432 aa)
Y51H1A.3Uncharacterized protein. (215 aa)
Y53G8AL.2NAD(P)-bd_dom domain-containing protein. (431 aa)
mrpl-17Mitochondrial Ribosomal Protein, Large. (194 aa)
nduf-5NADH Ubiquinone oxidoreductase Fe-S protein. (121 aa)
mrps-25Probable 28S ribosomal protein S25, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS25 family. (170 aa)
Y55F3AM.13Uncharacterized protein. (354 aa)
immp-2Inner Mitochondrial Membrane Protease. (152 aa)
Y55F3BL.4SRR1 domain-containing protein. (237 aa)
polg-1POLAc domain-containing protein. (1072 aa)
coq-3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (268 aa)
nuo-3NADH Ubiquinone Oxidoreductase. (131 aa)
mrps-728S ribosomal protein S7, mitochondrial; Belongs to the universal ribosomal protein uS7 family. (222 aa)
Y63D3A.7L51_S25_CI-B8 domain-containing protein. (92 aa)
tin-10Mitochondrial import inner membrane translocase subunit Tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (Probable). (86 aa)
micu-1Calcium uptake protein 1 homolog, mitochondrial; Key regulator of mitochondrial calcium uniporter (MCU). (534 aa)
Y67H2A.7Peptidase_M3 domain-containing protein. (692 aa)
mppa-1Mitochondrial-processing peptidase subunit alpha; Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. (514 aa)
Y82E9BR.3ATP synthase lipid-binding protein, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism [...] (116 aa)
Y92H12BR.3Uncharacterized protein Y92H12BR.3. (637 aa)
mrpl-15Ribosomal_L18e/L15P domain-containing protein. (298 aa)
Y94A7B.11Uncharacterized protein. (69 aa)
ZC262.5Putative ATP synthase subunit epsilon, mitochondrial. (54 aa)
mrps-18AMitochondrial Ribosomal Protein, Small. (183 aa)
mrpl-42Mitochondrial Ribosomal Protein, Large. (109 aa)
mppb-1Mitochondrial-processing peptidase subunit beta; Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (Probable). Preferentially, cleaves after an arginine at position P2 (Probable). (458 aa)
coa-6Cytochrome Oxidase Assembly subunits. (471 aa)
mtx-2Metaxin-2 homolog. (260 aa)
mrps-23Probable 28S ribosomal protein S23, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS23 family. (133 aa)
ZK287.1CRC domain-containing protein. (497 aa)
ZK470.1Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (180 aa)
tomm-7Mitochondrial import receptor subunit TOM7 homolog; Belongs to the Tom7 family. (58 aa)
ZK686.2Putative ATP-dependent RNA helicase ZK686.2; Probable ATP-binding RNA helicase; Belongs to the DEAD box helicase family. (593 aa)
ZK686.5Putative zinc finger protein ZK686.5. (263 aa)
ZK809.3Uncharacterized protein. (210 aa)
lpd-5LiPid Depleted. (176 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: medium (44%) [HD]