STRINGSTRING
egas-3 egas-3 del-8 del-8 del-9 del-9 delm-2 delm-2 acd-1 acd-1 acd-2 acd-2 acd-3 acd-3 unc-105 unc-105 del-7 del-7 deg-1 deg-1 del-1 del-1 flr-1 flr-1 mec-10 mec-10 delm-1 delm-1 degt-1 degt-1 del-3 del-3 acd-4 acd-4 egas-4 egas-4 del-5 del-5 unc-8 unc-8 mec-4 mec-4 del-6 del-6 del-4 del-4 del-10 del-10 acd-5 acd-5 asic-2 asic-2 Y57G11C.44 Y57G11C.44 egas-1 egas-1 egas-2 egas-2 asic-1 asic-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
egas-3EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (921 aa)
del-8DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (553 aa)
del-9DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (579 aa)
delm-2DEgenerin Linked to Mechanosensation; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (608 aa)
acd-1Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (635 aa)
acd-2Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (693 aa)
acd-3Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (484 aa)
unc-105Degenerin-like protein unc-105; Ion channel which is permeable to small monovalent cations. Shown not to be H+-ion gated. May be mechanosensitive and is required for growth and muscle development; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (962 aa)
del-7DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (614 aa)
deg-1Degenerin deg-1; Probable sodium channel subunit. Required by a subset of neurons. (778 aa)
del-1Degenerin del-1; Probable sodium channel subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (694 aa)
flr-1FLR-1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (638 aa)
mec-10Degenerin mec-10; Amiloride-sensitive sodium channel subunit required for mechanosensory transduction (touch sensitivity). Negatively regulates the turning step of male mating behavior. (724 aa)
delm-1DEgenerin Linked to Mechanosensation; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (626 aa)
degt-1DEGenerin-related Touch-involved channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (852 aa)
del-3DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (487 aa)
acd-4Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (613 aa)
egas-4EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (883 aa)
del-5DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (526 aa)
unc-8Degenerin unc-8. (778 aa)
mec-4Degenerin mec-4; Probable sodium channel subunit. May be needed for mechanosensory transduction (touch sensitivity). Negatively regulates the turning step of male mating behavior. (768 aa)
del-6DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (577 aa)
del-4DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (527 aa)
del-10Degenerin-like protein del-10. (1069 aa)
acd-5Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (714 aa)
asic-2Degenerin-like protein asic-2. (545 aa)
Y57G11C.44Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (155 aa)
egas-1EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (938 aa)
egas-2EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (919 aa)
asic-1Degenerin-like protein asic-1; Proton-gated cation channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions (By similarity). (823 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.