(27 nodes) PAN/Apple domain network (Caenorhabditis elegans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	noah-2	NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A). (741 aa)
	noah-1	NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A). (1052 aa)
	C34C12.7	Uncharacterized protein C34C12.7. (284 aa)
	C30H6.5	Uncharacterized protein. (530 aa)
	cutl-27	CUTiclin-Like. (969 aa)
	let-653	Protein let-653; Required for epithelial tube development and shaping. Involved in the morphogenesis and function of the three unicellular tubes of the excretory system, the canal cell, the duct cell and the pore cell. Also plays a role in cuticle development, alae formation and shaping of the vulval lumen. Required for larval development. (812 aa)
	C16D9.1	Uncharacterized protein. (398 aa)
	svh-1	Serine protease svh-1; Serine protease which ensures proper pharyngeal pumping during larval growth by regulating the levels of extracellular matrix component fbl-1. Independently of its enzymatic activity and probably by acting as a ligand for tyrosine-protein kinase receptor svh-2, involved in axon regeneration after injury by promoting the generation of productive and stable growth cones. May play a role in gonad development. (951 aa)
	B0361.9	Uncharacterized protein B0361.9. (194 aa)
	ZC449.2	Uncharacterized protein. (453 aa)
	ZC449.1	Uncharacterized protein. (454 aa)
	Y6G8.16	Apple domain-containing protein. (151 aa)
	Y6G8.15	Apple domain-containing protein. (151 aa)
	Y6G8.14	Apple domain-containing protein. (156 aa)
	T26C5.2	Uncharacterized protein. (595 aa)
	T21B6.3	Apple domain-containing protein. (821 aa)
	srap-1	Serine Rich Adhesion Protein-like. (3676 aa)
	T05B9.2	Apple domain-containing protein. (247 aa)
	R07A4.4	Uncharacterized protein. (573 aa)
	H42K12.3	Uncharacterized protein. (522 aa)
	H03E18.1	Uncharacterized protein. (1147 aa)
	F52C9.5	Uncharacterized protein F52C9.5. (618 aa)
	F48C5.2	Apple domain-containing protein. (170 aa)
	cutl-18	CUTiclin-Like. (801 aa)
	cutl-28	CUTiclin-Like. (696 aa)
	cutl-17	CUTiclin-Like. (912 aa)
	F32B4.8	Uncharacterized protein. (846 aa)

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H03E18.1	H42K12.3	H03E18.1.1	H42K12.3.1	Uncharacterized protein.	Uncharacterized protein.	0.917
H03E18.1	T26C5.2	H03E18.1.1	T26C5.2.1	Uncharacterized protein.	Uncharacterized protein.	0.615
H03E18.1	ZC449.1	H03E18.1.1	ZC449.1.1	Uncharacterized protein.	Uncharacterized protein.	0.406
H42K12.3	H03E18.1	H42K12.3.1	H03E18.1.1	Uncharacterized protein.	Uncharacterized protein.	0.917
H42K12.3	T26C5.2	H42K12.3.1	T26C5.2.1	Uncharacterized protein.	Uncharacterized protein.	0.568
H42K12.3	ZC449.1	H42K12.3.1	ZC449.1.1	Uncharacterized protein.	Uncharacterized protein.	0.591
H42K12.3	cutl-28	H42K12.3.1	F41A4.1.1	Uncharacterized protein.	CUTiclin-Like.	0.419
H42K12.3	noah-2	H42K12.3.1	F52B11.3.1	Uncharacterized protein.	NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A).	0.554
T26C5.2	H03E18.1	T26C5.2.1	H03E18.1.1	Uncharacterized protein.	Uncharacterized protein.	0.615
T26C5.2	H42K12.3	T26C5.2.1	H42K12.3.1	Uncharacterized protein.	Uncharacterized protein.	0.568
T26C5.2	ZC449.1	T26C5.2.1	ZC449.1.1	Uncharacterized protein.	Uncharacterized protein.	0.538
ZC449.1	H03E18.1	ZC449.1.1	H03E18.1.1	Uncharacterized protein.	Uncharacterized protein.	0.406
ZC449.1	H42K12.3	ZC449.1.1	H42K12.3.1	Uncharacterized protein.	Uncharacterized protein.	0.591
ZC449.1	T26C5.2	ZC449.1.1	T26C5.2.1	Uncharacterized protein.	Uncharacterized protein.	0.538
ZC449.1	ZC449.2	ZC449.1.1	ZC449.2.1	Uncharacterized protein.	Uncharacterized protein.	0.494
ZC449.2	ZC449.1	ZC449.2.1	ZC449.1.1	Uncharacterized protein.	Uncharacterized protein.	0.494
cutl-28	H42K12.3	F41A4.1.1	H42K12.3.1	CUTiclin-Like.	Uncharacterized protein.	0.419
let-653	noah-1	C29E6.1a.2	C34G6.6b.1	Protein let-653; Required for epithelial tube development and shaping. Involved in the morphogenesis and function of the three unicellular tubes of the excretory system, the canal cell, the duct cell and the pore cell. Also plays a role in cuticle development, alae formation and shaping of the vulval lumen. Required for larval development.	NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A).	0.738
let-653	noah-2	C29E6.1a.2	F52B11.3.1	Protein let-653; Required for epithelial tube development and shaping. Involved in the morphogenesis and function of the three unicellular tubes of the excretory system, the canal cell, the duct cell and the pore cell. Also plays a role in cuticle development, alae formation and shaping of the vulval lumen. Required for larval development.	NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A).	0.517
noah-1	let-653	C34G6.6b.1	C29E6.1a.2	NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A).	Protein let-653; Required for epithelial tube development and shaping. Involved in the morphogenesis and function of the three unicellular tubes of the excretory system, the canal cell, the duct cell and the pore cell. Also plays a role in cuticle development, alae formation and shaping of the vulval lumen. Required for larval development.	0.738