STRINGSTRING
cids-1 cids-1 C07A12.7 C07A12.7 hgrs-1 hgrs-1 C07H6.4 C07H6.4 unc-11 unc-11 rsd-3 rsd-3 stam-1 stam-1 nrd-1 nrd-1 tag-138 tag-138 cids-2 cids-2 tag-65 tag-65 pcf-11 pcf-11 epn-1 epn-1 apt-9 apt-9 ZC239.4 ZC239.4 hipr-1 hipr-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cids-1CID domain-containing protein 1. (315 aa)
C07A12.7GAT domain-containing protein. (437 aa)
hgrs-1Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. (729 aa)
C07H6.4Uncharacterized protein. (933 aa)
unc-11Phosphatidylinositol-binding clathrin assembly protein unc-11; Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. Required for the efficient targeting of the synaptic vesicle protein synaptobrevin. Belongs to the PICALM/SNAP91 family. (657 aa)
rsd-3ENTH domain-containing protein. (483 aa)
stam-1Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. (457 aa)
nrd-1NRD (Yeast Nuclear pre-mRNA Down-regulation) homolog. (988 aa)
tag-138ENTH domain-containing protein. (362 aa)
cids-2CID domain-containing protein. (664 aa)
tag-65SR-related CTD associated factor 6. (675 aa)
pcf-11Polyadenylation and cleavage factor homolog 11. (823 aa)
epn-1ENTH domain-containing protein. (469 aa)
apt-9AdaPTin or adaptin-related protein. (588 aa)
ZC239.4BTB domain-containing protein. (231 aa)
hipr-1Huntington interacting protein related 1; Regulates pre-synaptic vesicle recycling at neuromuscular junctions of mechanosensory neurons. Plays a role in maintaining a normal defecation cycle; Belongs to the SLA2 family. (927 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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