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| | ZK1248.17 | MSP domain-containing protein. (95 aa) |
| | unc-5 | Netrin receptor unc-5; Receptor for netrin (unc-6) required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon migration is mediated by the secreted unc-6, which promotes attraction of neurons and axons through binding to the unc-40 receptor, while repulsion requires both unc-5 and unc-40 receptors. Involved in the ventral-dorsal and anterior-posterior migration of distal tip cells along the body, which may be mediated by Wnt receptor mom-5, ced- 10/Rac, ced-12/ELMO and mig-2/RhoG. (947 aa) |
| | hpo-28 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (567 aa) |
| | C01F6.2 | AMPK1_CBM domain-containing protein. (487 aa) |
| | C01G10.14 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (150 aa) |
| | cam-1 | Tyrosine-protein kinase receptor cam-1; Tyrosine-protein kinase receptor for Wnt ligands egl-20, mom- 2 and cwn-1. Involved in the final positioning of migrating ALM, CAN, BDU and HSN neurons during development. Involved in the anterior-posterior migration of QR neuroblast descendants, QR.p and QR.pa, by maintaining QR.p cell polarization, probably through mig-2. In addition, plays a role in ASI sensory neuron positioning and functions. Regulates asymmetric division of V cells (seam cells) and CA/CP neuroblast, and axon outgrowth. Probably by acting as a receptor for Wnt ligand cwn- 2, [...] (928 aa) |
| | msp-36 | Major sperm protein 10/36/56/76; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (127 aa) |
| | C05D9.9 | Uncharacterized protein. (139 aa) |
| | msp-55 | Major sperm protein 55/57; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (127 aa) |
| | zig-4 | Zwei Ig domain protein zig-4; Required for maintaining axon position of PVQ and PVP neurons postembryonically in the ventral nerve cord (VNC) by preventing axons drifting into the opposite side of the VNC that could occur during body growth and movement. (253 aa) |
| | unc-89 | Muscle M-line assembly protein unc-89; Structural component of the muscle M line which is involved in assembly and organization of sarcomere myofilaments. The large isoform a, isoform b, isoform d and isoform f play an essential role in maintaining the organization of sarcomeres but not myofilament alignment during body wall muscle development whereas the small isoform c and isoform d appear to have a minor role. Isoform b and isoform f are required for the organization of unc-15/paramyosin into sarcomere thick filaments in body wall muscles. By binding mel-26, a substrate adapter of t [...] (8081 aa) |
| | ptp-3 | Tyrosine-protein phosphatase Lar-like; Has a role in early neural and epidermal development; neuroblast movements during closure of the gastrulation cleft and epidermal morphogenesis. Vab-1 and ptp-3 may function redundantly within the same sets of neuronal precursors. (2248 aa) |
| | oig-1 | Immunoglobulin domain-containing protein oig-1; Plays a role in neural development, where it temporally regulates synapse formation in the D-type inhibitory GABAergic motor neurons, dorsal D (DD) and ventral D (VD) motor neurons. Controls the translocation of postsynaptic proteins, such as the acetylcholine receptor subunit acr- 12, and presynaptic proteins, such as snb-1, along nerve cords to prevent premature synapse remodeling/formation. (137 aa) |
| | C10H11.7 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (177 aa) |
| | lin-41 | Protein lin-41; Heterochronic protein which acts downstream of let-7 in temporal patterning. Plays a role in the developmental timing of postembryonic hypodermal seam cell division and fusion events and adult alae production. Represses lin-29 during late larval stages, which prevents terminal differentiation of hypodermal seam cells and promotes their division. Involved in post-transcriptional gene regulation, uses two independent pathways. Has direct and specific RNA-binding activity and, depending on the location (5'UTR or 3'UTR) of the target site, triggers either mRNA decay or repr [...] (1147 aa) |
| | C14A4.8 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (228 aa) |
| | zig-3 | Zwei Ig domain protein zig-3; Required for maintaining axon position of PVQ and PVP neurons postembryonically in the ventral nerve cord (VNC) by preventing axons drifting into the opposite side of the VNC that could occur during body growth and movement. (251 aa) |
| | C15H11.1 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (122 aa) |
| | ocrl-1 | Rho-GAP domain-containing protein. (768 aa) |
| | rol-3 | Protein roller-3; Thought to have a role in developmental establishment of posterior morphology. (2481 aa) |
| | dim-1 | Disorganized muscle protein 1; Stabilizes the attachment of the myofilament lattice to the muscle cell membrane. Isoform b is sufficient for wild-type function. (640 aa) |
| | C18E9.7 | Uncharacterized protein. (893 aa) |
| | sax-7 | Fibronectin type-III domain-containing protein. (1331 aa) |
| | fln-2 | FiLamiN (Actin binding protein) homolog. (3672 aa) |
| | C25D7.1 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (150 aa) |
| | igdb-2 | Ig-like and fibronectin type-III domain-containing protein 2. (1526 aa) |
| | syg-2 | Synaptogenesis protein syg-2; Cell adhesion protein. Determines synapse formation. Required for correct localization of syg-1 at synaptic sites. (1230 aa) |
| | C27B7.7 | Ig-like and fibronectin type-III domain-containing protein C27B7.7. (1456 aa) |
| | rig-6 | Contactin rig-6; Probable cell adhesion protein involved in patterning of the nervous system, playing a role in ALM and PLM touch receptor axon growth and VNC axon navigation. By associating with the transmembrane protein sax-7, mediates axonal interactions to establish synaptic connections between the AVG interneuron and the two PHC sensory neurons. Also required for non-neuronal cell migration in the excretory canal, regulating excretory canal elongation and excretory cell morphogenesis. Plays a role in regulating male mating behavior. (1196 aa) |
| | msp-40 | Major sperm protein 19/31/40/45/50/51/53/59/61/65/81/113/142; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (127 aa) |
| | C33G3.4 | Probable beta-mannosidase; Belongs to the glycosyl hydrolase 2 family. (900 aa) |
| | C34D10.1 | MSP domain-containing protein. (205 aa) |
| | C34D4.3 | MSP domain-containing protein. (117 aa) |
| | msp-49 | Major sperm protein 49; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (127 aa) |
| | C34F6.10 | Uncharacterized protein. (1465 aa) |
| | C35A5.4 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (427 aa) |
| | msd-4 | MSP domain-containing protein. (109 aa) |
| | C35E7.9 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (301 aa) |
| | cle-1 | CoLlagen with Endostatin domain. (1175 aa) |
| | C36E6.2 | N_BRCA1_IG domain-containing protein. (239 aa) |
| | rig-5 | Ig-like domain-containing protein. (482 aa) |
| | C36H8.1 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (418 aa) |
| | mig-6 | Papilin; Involved in pharynx morphogenesis probably by remodeling the basement membrane. [Isoform b]: Plays a role in post embryonic distal cell tip migration. Essential extracellular matrix (ECM) protein required for hypodermal enclosure in the embryo. (2167 aa) |
| | madd-2 | Uncharacterized protein. (765 aa) |
| | hcf-1 | Host cell factor 1. (782 aa) |
| | C53A5.13 | Uncharacterized protein. (681 aa) |
| | rig-3 | Neuronal immunoglobulin domain-containing protein rig-3; Cell surface protein which plays a role in the plasticity of cholinergic synapses at neuromuscular junctions and in the polarity of the mechanosensory neuron ALM, possibly by antagonizing Wnt signaling. (487 aa) |
| | ssp-19 | Sperm-specific class P protein 19. (109 aa) |
| | D2007.2 | Uncharacterized protein D2007.2. (248 aa) |
| | ssp-9 | Sperm-specific class P protein 9/11. (109 aa) |
| | ncam-1 | NCAM (Neural cell adhesion molecule) homolog. (955 aa) |
| | F13A7.1 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (340 aa) |
| | F13H8.12 | MSP domain-containing protein. (128 aa) |
| | him-4 | EGF-like domain-containing protein. (5213 aa) |
| | iglr-1 | Ig-like domain-containing protein. (695 aa) |
| | F21C10.7 | Uncharacterized protein. (2588 aa) |
| | F21H7.5 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (306 aa) |
| | malt-1 | MALT1 paracaspase homolog. (639 aa) |
| | F22D6.15 | Uncharacterized protein. (127 aa) |
| | msp-3 | Major sperm protein 3; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (127 aa) |
| | spe-45 | Ig-like domain-containing protein. (492 aa) |
| | igeg-1 | IG (Immunoglobulin), EGF and transmmembrane domain. (274 aa) |
| | msp-77 | Major sperm protein 77/79; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (127 aa) |
| | ssp-32 | Sperm-specific class P protein 32. (107 aa) |
| | spd-2 | Spindle-defective protein 2; Required both for centrosome duplication and maturation. Required for pericentriolar material (PCM) recruitment. (824 aa) |
| | vpr-1 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (245 aa) |
| | twk-30 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (608 aa) |
| | F36D3.4 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (285 aa) |
| | F36H12.3 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (335 aa) |
| | F38H4.6 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (156 aa) |
| | igcm-1 | ImmunoGlobulin-like Cell adhesion Molecule family. (1073 aa) |
| | wrk-1 | Wrapper/Rega-1/Klingon homolog. (452 aa) |
| | F42A9.7 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (267 aa) |
| | zig-2 | Zwei Ig domain protein zig-2; Probably not involved in maintaining the position of ASI and ASH head neuron cell bodies and ventral nerve cord axons of PVQ, PVP, RMEV, AVK and HSN neurons. (238 aa) |
| | F42G2.5 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (374 aa) |
| | dep-1 | Receptor-type tyrosine-protein phosphatase dep-1; Phosphatase which may dephosphorylate receptor let-23 and thereby regulate cell fate during the development of the vulva and the excretory system. By inhibiting let-23 signaling prevents the establishment of a primary cell fate in the descendants of vulva precursor cells P5.p and P7.p. Similarly, may prevent duct cell fate in ABpr precursor. Also dephosphorylates the beta-integrin subunit pat-3, probably within the alpha pat-2/beta pat-3 integrin receptor complex, which leads to down- stream effects including the negative regulation of [...] (1367 aa) |
| | F46H5.7 | Uncharacterized protein. (575 aa) |
| | igeg-2 | IG (Immunoglobulin), EGF and transmmembrane domain. (264 aa) |
| | F52F12.8 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (123 aa) |
| | madd-4 | Protein madd-4; Component of an extracellular matrix cue that is involved in the guidance of dorsoventral midline migrations and in the specification of postsynaptic domains at neuromuscular junctions (NMJs). Acts as a ligand for the netrin receptor unc-40 and the neuroligin receptor nlg-1. Secreted by the dorsal and ventral nerve cords to attract sensory axons and muscle membrane extensions called muscle arms. In parallel with unc-6 and slt-1, involved in the netrin receptor unc-40 dependent guidance of the AVM and PVM mechanosensory axons along the dorsal-ventral axis. The unc-40 cor [...] (1045 aa) |
| | F53B6.4 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (342 aa) |
| | twk-32 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (614 aa) |
| | zig-7 | Zwei Ig domain protein zig-7; Probably not involved in maintaining the position of ASI and ASH head neuron cell bodies and ventral nerve cord axons of PVQ, PVP, RMEV, AVK and HSN neurons. (239 aa) |
| | ketn-1 | KETtiN (Drosophila actin-binding) homolog. (4963 aa) |
| | F54H5.3 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (279 aa) |
| | ssp-35 | MSP domain-containing protein. (107 aa) |
| | unc-73 | Guanine nucleotide exchange factor UNC-73A. (2488 aa) |
| | aakb-1 | AMPKBI domain-containing protein. (269 aa) |
| | clr-1 | Receptor-type tyrosine-protein phosphatase; Possesses an intrinsic protein tyrosine phosphatase (PTPase) activity. Regulates egl-15 activity which is required for hypodermis-mediated fluid homeostasis and protein degradation in muscle. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles. Plays a role in nicotinic acetylcholine receptor (nAChR)-mediated sensitivity to nicotine. Regulates synaptic levels of nAchR subunit lev-1 in the nerve cord. Promotes the outgrowth of the quaternary dendritic branches of [...] (1444 aa) |
| | F57A10.2 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (155 aa) |
| | egl-15 | Myoblast growth factor receptor egl-15; Receptor tyrosine kinase required for larval development. May phosphorylate adapter protein soc-1 which in turn may result in the recruitment and/or activation of phosphatase ptp-2. May activate the Ras/MAPK kinase signaling pathway which includes sem-5, sos-1, let-60/Ras, lin-45/Raf, mek-2 and mpk-1. Acts in the hypodermis to regulate axon growth and fluid homeostasis. Activates protein degradation in muscles. Probably following interaction with ligand let-756, regulates negatively membrane protrusion from body wall muscles during larval develop [...] (1157 aa) |
| | F58A3.4 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (138 aa) |
| | F58E6.5 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (304 aa) |
| | ver-3 | Tyrosine-protein kinase receptor ver-3; Receptor tyrosine kinase which may be involved, downstream of pvf-1, in the positioning of ray 1, the most anterior ray sensillum in the male tail. (1227 aa) |
| | ver-4 | Tyrosine-protein kinase receptor ver-4; Receptor tyrosine kinase which may be involved, downstream of pvf-1, in the positioning of ray 1, the most anterior ray sensillum in the male tail. (1216 aa) |
| | let-805 | Myotactin form B. (4450 aa) |
| | syg-1 | Synaptogenesis protein syg-1; Cell adhesion protein. Involved in synapse formation in the HSNL egg-laying motor neuron. Inhibits assembly of the SCF(sel-10) E3 ubiquitin ligase complex at synapses, and protects them from elimination. Also required for F- actin assembly at the synaptic region and for axon branch formation. (730 aa) |
| | kal-1 | KALlmann syndrome homolog. (700 aa) |
| | K03H1.5 | Uncharacterized protein K03H1.5. (1385 aa) |
| | plx-2 | Plexin-2; Involved as a receptor for mab-20/sema-2a in the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, involved in precursor cell sorting and in the formation of distinct sensory rays. Involved in axon guidance of SDQL neurons during neurogenesis. Probably in response to stimulation by mab-20, regulates fln-1-mediated remodeling of the actin cytoskeleton and thus axon guidance and/or fasciculation of DD/VD neurons. Bel [...] (1766 aa) |
| | ptp-4 | Tyrosine-protein phosphatase 4. (1159 aa) |
| | msp-63 | Major sperm protein 63; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (127 aa) |
| | K05F1.9 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (218 aa) |
| | K06A5.3 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (145 aa) |
| | dig-1 | Mesocentin; Encodes an adhesion molecule involved in sensory map formation. Functions during sensory process development in the nervous system. (13100 aa) |
| | K07F5.7 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (134 aa) |
| | ssp-10 | Sperm-specific class P protein 10. (109 aa) |
| | lag-1 | Lin-12 And Glp-1 phenotype. (790 aa) |
| | K08E3.2 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (276 aa) |
| | msp-38 | Major sperm protein 38; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (127 aa) |
| | pxn-2 | PeroXidasiN (Drosophila peroxidase) homolog. (1328 aa) |
| | rig-1 | NeuRonal IGCAM. (1147 aa) |
| | gpcp-1 | Putative glycerophosphocholine phosphodiesterase GPCPD1 homolog 1. (690 aa) |
| | zig-1 | Zwei Ig domain protein zig-1; Probably not involved in maintaining the position of ASI and ASH head neuron cell bodies and ventral nerve cord axons of PVQ, PVP, RMEV, AVK and HSN neurons. (265 aa) |
| | zig-12 | Ig-like domain-containing protein. (197 aa) |
| | vab-1 | Ephrin receptor 1; Receptor for members of the ephrin family (By similarity). Receptor for major sperm proteins (MSPs), that functions as sperm- sensing checkpoint which inhibits oocyte meiotic maturation and ovulation when sperm are not available for fertilization. Specifically, functions to negatively regulates oocyte maturation and MAPK activation in the absence of MSPs. Required for the MSP-mediated increase in the basal sheath cell contraction rate in somatic cells. Phosphorylates phosphatase daf-18/PTEN which probably promotes daf-18 degradation. By inactivating daf-18, regulates [...] (1122 aa) |
| | M03E7.1 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (146 aa) |
| | M199.2 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (488 aa) |
| | R05D3.5 | Uncharacterized protein R05D3.5. (178 aa) |
| | msp-32 | Major sperm protein 32; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (119 aa) |
| | msp-33 | Major sperm protein 33; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (127 aa) |
| | R07E4.1 | Uncharacterized protein. (1122 aa) |
| | oig-4 | Immunoglobulin domain-containing protein oig-4; Required for the localization of acetylcholine receptors at neuromuscular junctions and for subsequently controlling the response evoked by receptor stimulation. (155 aa) |
| | ssp-33 | MSP domain-containing protein. (107 aa) |
| | igcm-2 | ImmunoGlobulin-like Cell adhesion Molecule family. (718 aa) |
| | igcm-3 | ImmunoGlobulin-like Cell adhesion Molecule family. (591 aa) |
| | zig-6 | Zwei Ig domain protein zig-6; Probably not involved in maintaining the position of ASI and ASH head neuron cell bodies and ventral nerve cord axons of PVQ, PVP, RMEV, AVK and HSN neurons. (243 aa) |
| | T04A8.7 | Aamy domain-containing protein. (681 aa) |
| | camt-1 | CAMTA (CAlModulin-binding Transcriptional activator). (1185 aa) |
| | T05D4.5 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (482 aa) |
| | gpcp-2 | Putative glycerophosphocholine phosphodiesterase GPCPD1 homolog 2. (796 aa) |
| | msp-78 | Major sperm protein 78; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (127 aa) |
| | ssp-36 | MSP domain-containing protein. (107 aa) |
| | ver-1 | Protein ver-1; Involved in amphid glia remodeling during entry into dauer stage by promoting the fusion of sheath amphid cells which encloses AWC neuron sensory endings. May be involved, downstream of pvf-1, in the positioning of ray 1, the most anterior ray sensillum in the male tail. (1083 aa) |
| | zig-13 | 2 (Zwei) IG domain protein. (352 aa) |
| | unc-40 | Unc-40 protein. (1415 aa) |
| | oig-8 | Ig-like domain-containing protein. (285 aa) |
| | osm-10 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (419 aa) |
| | dgn-1 | Peptidase S72 domain-containing protein. (584 aa) |
| | sma-10 | Leucine-rich repeats and immunoglobulin-like domains protein sma-10; Binds to the TGF-beta receptors sma-6 and daf-4, and enhances TGF-beta signaling activity in vitro. Has a role in regulation of body size. (881 aa) |
| | T22B3.3 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (185 aa) |
| | igdb-3 | IG (Immunoglobulin) and DB (Cys-rich) domains. (547 aa) |
| | sec-5 | Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (884 aa) |
| | zig-10 | 2 (Zwei) IG domain protein. (322 aa) |
| | ssp-16 | Sperm-specific class P protein 16. (109 aa) |
| | ssp-37 | MSP domain-containing protein. (112 aa) |
| | W03D8.5 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (267 aa) |
| | dct-9 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (183 aa) |
| | nhl-3 | B box-type domain-containing protein. (698 aa) |
| | ttn-1 | Titin homolog; Serine/threonine-protein kinase. Key component in the assembly and functioning of muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase (By similarity). (15188 aa) |
| | W08E3.4 | Uncharacterized protein. (267 aa) |
| | igcm-4 | ImmunoGlobulin-like Cell adhesion Molecule family. (541 aa) |
| | Y105C5B.19 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (484 aa) |
| | jac-1 | Juxtamembrane domain-associated catenin; May act as a positive modulator of hmr-1 function during epidermal morphogenesis. Required for proper localization of other junctional components, such as pac-1 ; Belongs to the beta-catenin family. (1256 aa) |
| | Y105E8B.9 | Uncharacterized protein. (628 aa) |
| | Y116A8A.2 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (169 aa) |
| | Y116A8A.7 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (167 aa) |
| | zig-9 | Ig-like domain-containing protein. (283 aa) |
| | unc-3 | Transcription factor unc-3; May play a role in the expression of proteins essential for axonal pathfinding and/or neuronal differentiation in both sensory and motor neurons. Cooperates with jmjd-3.1 and wdr-5.1 to ensure robust transdifferentiation of the Y rectal cell to the PDA motor neuron during larval development. (491 aa) |
| | spe-47 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (380 aa) |
| | zig-11 | Ig-like domain-containing protein. (304 aa) |
| | iglr-3 | Ig-like domain-containing protein. (488 aa) |
| | oig-2 | Ig-like domain-containing protein. (108 aa) |
| | Y38F2AR.10 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (184 aa) |
| | rimb-1 | RIM Binding protein. (1276 aa) |
| | zig-8 | Zwei Ig domain protein zig-8; Together with zig-5, required postembryonically to maintain the position of ASI and ASH head neuron cell bodies and ventral nerve cord axons of PVQ, PVP and HSN neurons by preventing their displacement that could occur during body growth and movement. May act by reducing L1CAM-like protein sax-7 (long isoform) adhesion. (268 aa) |
| | Y41C4A.7 | Uncharacterized protein. (248 aa) |
| | rig-4 | Protein sidekick homolog; Cell adhesion protein; Belongs to the sidekick family. (2325 aa) |
| | aakb-2 | AMPKBI domain-containing protein. (274 aa) |
| | zig-5 | Zwei Ig domain protein zig-5; Together with zig-8, required postembryonically to maintain the position of ASI and ASH head neuron cell bodies and ventral nerve cord axons of PVQ, PVP and HSN neurons by preventing their displacement that could occur during body growth and movement. May act by reducing L1CAM-like protein sax-7 (long isoform) adhesion. (260 aa) |
| | Y48B6A.5 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (424 aa) |
| | Y50E8A.2 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (137 aa) |
| | oig-3 | Ig-like domain-containing protein. (151 aa) |
| | Y53C10A.15 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (162 aa) |
| | Y53F4B.19 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (338 aa) |
| | lad-2 | Immunoglobulin domain-containing protein Y54G2A.25. (1187 aa) |
| | daf-2 | Insulin-like receptor subunit alpha; Insulin receptor-like tyrosine kinase which regulates metabolism, controls longevity and prevents developmental arrest at the dauer stage. Binding of INS family members may either stimulate, or antagonize, association of the receptor with downstream mediators such as pdk-1 and age-1. Required for germline progenitor proliferation during larval development. Required for the response to environmental stimuli such as food, pheromone, and temperature. Negatively regulates resistance to UV and oxidative stress. Role in immune function and pathogen resist [...] (1928 aa) |
| | plx-1 | Sema domain-containing protein. (1956 aa) |
| | oig-5 | Ig-like domain-containing protein. (164 aa) |
| | Y59E9AR.1 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (130 aa) |
| | Y59H11AM.1 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (127 aa) |
| | fln-1 | Calponin-homology (CH) domain-containing protein. (2259 aa) |
| | mab-20 | Semaphorin-2A; Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, regulates precursor cell sorting and allows the formation of distinct sensory rays. Seems to control cell-cell contact formation through 2 parallel pathways, one involving efn-4 and one involving plx-2 and unc-129. Involved in axon guidance. Probably by binding receptor plx-2, regulates fln-1-mediated remodeling of the actin cytoskeleton and thus [...] (658 aa) |
| | unc-52 | Basement membrane proteoglycan; Component of an integrin containing attachment complex, which is required for muscle development and maintenance. Probable structural role in myofilament assembly and/or attachment of the myofilament lattice to the cell membrane. May be an extracellular anchor for integrin receptors in body wall muscles and myoepithelial sheath cells. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably downstream of the integrin complex formed by pat-2 and pat-3. Involved in ovulation. (3375 aa) |
| | ssp-34 | Sperm-specific class P protein 34. (107 aa) |
| | ZC196.2 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (345 aa) |
| | ZC262.1 | Uncharacterized protein ZC262.1. (131 aa) |
| | iglr-2 | Immunoglobulin domain and leucine-rich repeat-containing protein 2. (773 aa) |
| | ZC374.2 | Uncharacterized protein. (684 aa) |
| | ssp-31 | Sperm-specific class P protein 31. (107 aa) |
| | ZK1307.3 | Uncharacterized protein ZK1307.3. (115 aa) |
| | ZK1307.4 | Uncharacterized protein ZK1307.4. (115 aa) |
| | tep-1 | TEP (ThiolEster containing Protein). (1516 aa) |
| | msp-58 | MSP domain-containing protein. (77 aa) |
| | ZK354.7 | Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (224 aa) |
| | sax-3 | Protein sax-3; Required to confine migrating sex myoblasts to the ventral muscle quadrants during their migration through the body and for multiple aspects of sensory, motor, and interneuron axon guidance. Belongs to the immunoglobulin superfamily. ROBO/SAX3 family. (1273 aa) |
| | msp-152 | Major sperm protein 152; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (127 aa) |
| | unc-22 | Twitchin; Regulator of muscle contraction and relaxation. Senses mechanical strain that occurs during muscle activity by unfolding in clearly resolvable steps at differing forces. Plays a role in the organization of sarcomeres in body wall muscles ; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (7158 aa) |
| | ZK688.12 | Uncharacterized protein ZK688.12. (173 aa) |
| | pxn-1 | Peroxidasin homolog; Belongs to the peroxidase family. XPO subfamily. (1285 aa) |
