Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| atl-1 | atm-1 | T06E4.3a.1 | Y48G1BL.2a.1 | Serine/threonine-protein kinase ATR; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor (By similarity). Recognizes the substrate consensus sequence [ST]-Q (By similarity). Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination (By similarity). Prevents mitotic catastrophe by functioning in the S-phase checkpoint and cooperating with atm-1 in the c [...] | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.996 |
| atl-1 | let-363 | T06E4.3a.1 | B0261.2a.1 | Serine/threonine-protein kinase ATR; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor (By similarity). Recognizes the substrate consensus sequence [ST]-Q (By similarity). Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination (By similarity). Prevents mitotic catastrophe by functioning in the S-phase checkpoint and cooperating with atm-1 in the c [...] | Target of rapamycin homolog; Serine/threonine-protein kinase that regulates the mRNA translation machinery, probably by modulating the activity of translation factors such as eIF-4G and eIF-2. It may have some protein kinase activity instead of lipid kinase activity. May play a role in P-granule degradation by autophagy in somatic cells during embryogenesis. Required, during larval development, for the establishment of the proper number of germline progenitors, probably upstream of rsks-1 and ife-1. Required for larval development. May act as a mediator of lifespan regulation by insuli [...] | 0.453 |
| atl-1 | smg-1 | T06E4.3a.1 | C48B6.6a.1 | Serine/threonine-protein kinase ATR; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor (By similarity). Recognizes the substrate consensus sequence [ST]-Q (By similarity). Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination (By similarity). Prevents mitotic catastrophe by functioning in the S-phase checkpoint and cooperating with atm-1 in the c [...] | Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2. | 0.505 |
| atl-1 | trr-1 | T06E4.3a.1 | C47D12.1a.1 | Serine/threonine-protein kinase ATR; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor (By similarity). Recognizes the substrate consensus sequence [ST]-Q (By similarity). Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination (By similarity). Prevents mitotic catastrophe by functioning in the S-phase checkpoint and cooperating with atm-1 in the c [...] | Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (By similarity). Required for spermatogenesis and embryonic development (By similarity). Acts with tra-2 to promote expression of fog-3 and control male tail development (By similarity). Involved in the negative regulation of vulval development. Belongs to the PI3/PI4-kinase family. TRA1 subfamily. | 0.546 |
| atm-1 | atl-1 | Y48G1BL.2a.1 | T06E4.3a.1 | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | Serine/threonine-protein kinase ATR; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor (By similarity). Recognizes the substrate consensus sequence [ST]-Q (By similarity). Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination (By similarity). Prevents mitotic catastrophe by functioning in the S-phase checkpoint and cooperating with atm-1 in the c [...] | 0.996 |
| atm-1 | let-363 | Y48G1BL.2a.1 | B0261.2a.1 | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | Target of rapamycin homolog; Serine/threonine-protein kinase that regulates the mRNA translation machinery, probably by modulating the activity of translation factors such as eIF-4G and eIF-2. It may have some protein kinase activity instead of lipid kinase activity. May play a role in P-granule degradation by autophagy in somatic cells during embryogenesis. Required, during larval development, for the establishment of the proper number of germline progenitors, probably upstream of rsks-1 and ife-1. Required for larval development. May act as a mediator of lifespan regulation by insuli [...] | 0.403 |
| atm-1 | smg-1 | Y48G1BL.2a.1 | C48B6.6a.1 | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2. | 0.488 |
| atm-1 | trr-1 | Y48G1BL.2a.1 | C47D12.1a.1 | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (By similarity). Required for spermatogenesis and embryonic development (By similarity). Acts with tra-2 to promote expression of fog-3 and control male tail development (By similarity). Involved in the negative regulation of vulval development. Belongs to the PI3/PI4-kinase family. TRA1 subfamily. | 0.690 |
| let-363 | atl-1 | B0261.2a.1 | T06E4.3a.1 | Target of rapamycin homolog; Serine/threonine-protein kinase that regulates the mRNA translation machinery, probably by modulating the activity of translation factors such as eIF-4G and eIF-2. It may have some protein kinase activity instead of lipid kinase activity. May play a role in P-granule degradation by autophagy in somatic cells during embryogenesis. Required, during larval development, for the establishment of the proper number of germline progenitors, probably upstream of rsks-1 and ife-1. Required for larval development. May act as a mediator of lifespan regulation by insuli [...] | Serine/threonine-protein kinase ATR; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor (By similarity). Recognizes the substrate consensus sequence [ST]-Q (By similarity). Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination (By similarity). Prevents mitotic catastrophe by functioning in the S-phase checkpoint and cooperating with atm-1 in the c [...] | 0.453 |
| let-363 | atm-1 | B0261.2a.1 | Y48G1BL.2a.1 | Target of rapamycin homolog; Serine/threonine-protein kinase that regulates the mRNA translation machinery, probably by modulating the activity of translation factors such as eIF-4G and eIF-2. It may have some protein kinase activity instead of lipid kinase activity. May play a role in P-granule degradation by autophagy in somatic cells during embryogenesis. Required, during larval development, for the establishment of the proper number of germline progenitors, probably upstream of rsks-1 and ife-1. Required for larval development. May act as a mediator of lifespan regulation by insuli [...] | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.403 |
| let-363 | smg-1 | B0261.2a.1 | C48B6.6a.1 | Target of rapamycin homolog; Serine/threonine-protein kinase that regulates the mRNA translation machinery, probably by modulating the activity of translation factors such as eIF-4G and eIF-2. It may have some protein kinase activity instead of lipid kinase activity. May play a role in P-granule degradation by autophagy in somatic cells during embryogenesis. Required, during larval development, for the establishment of the proper number of germline progenitors, probably upstream of rsks-1 and ife-1. Required for larval development. May act as a mediator of lifespan regulation by insuli [...] | Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2. | 0.590 |
| let-363 | trr-1 | B0261.2a.1 | C47D12.1a.1 | Target of rapamycin homolog; Serine/threonine-protein kinase that regulates the mRNA translation machinery, probably by modulating the activity of translation factors such as eIF-4G and eIF-2. It may have some protein kinase activity instead of lipid kinase activity. May play a role in P-granule degradation by autophagy in somatic cells during embryogenesis. Required, during larval development, for the establishment of the proper number of germline progenitors, probably upstream of rsks-1 and ife-1. Required for larval development. May act as a mediator of lifespan regulation by insuli [...] | Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (By similarity). Required for spermatogenesis and embryonic development (By similarity). Acts with tra-2 to promote expression of fog-3 and control male tail development (By similarity). Involved in the negative regulation of vulval development. Belongs to the PI3/PI4-kinase family. TRA1 subfamily. | 0.678 |
| smg-1 | atl-1 | C48B6.6a.1 | T06E4.3a.1 | Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2. | Serine/threonine-protein kinase ATR; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor (By similarity). Recognizes the substrate consensus sequence [ST]-Q (By similarity). Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination (By similarity). Prevents mitotic catastrophe by functioning in the S-phase checkpoint and cooperating with atm-1 in the c [...] | 0.505 |
| smg-1 | atm-1 | C48B6.6a.1 | Y48G1BL.2a.1 | Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2. | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.488 |
| smg-1 | let-363 | C48B6.6a.1 | B0261.2a.1 | Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2. | Target of rapamycin homolog; Serine/threonine-protein kinase that regulates the mRNA translation machinery, probably by modulating the activity of translation factors such as eIF-4G and eIF-2. It may have some protein kinase activity instead of lipid kinase activity. May play a role in P-granule degradation by autophagy in somatic cells during embryogenesis. Required, during larval development, for the establishment of the proper number of germline progenitors, probably upstream of rsks-1 and ife-1. Required for larval development. May act as a mediator of lifespan regulation by insuli [...] | 0.590 |
| smg-1 | trr-1 | C48B6.6a.1 | C47D12.1a.1 | Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2. | Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (By similarity). Required for spermatogenesis and embryonic development (By similarity). Acts with tra-2 to promote expression of fog-3 and control male tail development (By similarity). Involved in the negative regulation of vulval development. Belongs to the PI3/PI4-kinase family. TRA1 subfamily. | 0.842 |
| trr-1 | atl-1 | C47D12.1a.1 | T06E4.3a.1 | Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (By similarity). Required for spermatogenesis and embryonic development (By similarity). Acts with tra-2 to promote expression of fog-3 and control male tail development (By similarity). Involved in the negative regulation of vulval development. Belongs to the PI3/PI4-kinase family. TRA1 subfamily. | Serine/threonine-protein kinase ATR; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor (By similarity). Recognizes the substrate consensus sequence [ST]-Q (By similarity). Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination (By similarity). Prevents mitotic catastrophe by functioning in the S-phase checkpoint and cooperating with atm-1 in the c [...] | 0.546 |
| trr-1 | atm-1 | C47D12.1a.1 | Y48G1BL.2a.1 | Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (By similarity). Required for spermatogenesis and embryonic development (By similarity). Acts with tra-2 to promote expression of fog-3 and control male tail development (By similarity). Involved in the negative regulation of vulval development. Belongs to the PI3/PI4-kinase family. TRA1 subfamily. | Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.690 |
| trr-1 | let-363 | C47D12.1a.1 | B0261.2a.1 | Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (By similarity). Required for spermatogenesis and embryonic development (By similarity). Acts with tra-2 to promote expression of fog-3 and control male tail development (By similarity). Involved in the negative regulation of vulval development. Belongs to the PI3/PI4-kinase family. TRA1 subfamily. | Target of rapamycin homolog; Serine/threonine-protein kinase that regulates the mRNA translation machinery, probably by modulating the activity of translation factors such as eIF-4G and eIF-2. It may have some protein kinase activity instead of lipid kinase activity. May play a role in P-granule degradation by autophagy in somatic cells during embryogenesis. Required, during larval development, for the establishment of the proper number of germline progenitors, probably upstream of rsks-1 and ife-1. Required for larval development. May act as a mediator of lifespan regulation by insuli [...] | 0.678 |
| trr-1 | smg-1 | C47D12.1a.1 | C48B6.6a.1 | Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (By similarity). Required for spermatogenesis and embryonic development (By similarity). Acts with tra-2 to promote expression of fog-3 and control male tail development (By similarity). Involved in the negative regulation of vulval development. Belongs to the PI3/PI4-kinase family. TRA1 subfamily. | Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2. | 0.842 |