STRINGSTRING
F38E9.1 F38E9.1 gpcp-1 gpcp-1 plc-1 plc-1 egl-8 egl-8 pll-1 pll-1 plc-4 plc-4 plc-3 plc-3 gpcp-2 gpcp-2 T09B9.3 T09B9.3 T12B3.3 T12B3.3 T22G5.1 T22G5.1 plc-2 plc-2 ZC155.4 ZC155.4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F38E9.1Uncharacterized protein. (569 aa)
gpcp-1Putative glycerophosphocholine phosphodiesterase GPCPD1 homolog 1. (690 aa)
plc-11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. plc-1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity (By similarity). By activating IP3 receptor itr-1-mediated intracellular Ca(2+) release via the production of IP3, regulates ovulation by controlling contraction and/or dilation of the di [...] (1898 aa)
egl-81-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) which plays an important role in the regulation of intracellular signaling cascades (By similarity). Required in the nervous system to modulate neuronal activity. Facilitates synaptic transmission at neuromuscular junctions by regulating the release of acetylcholine from the motor neurons and thus affecting locomotion. Plays a role in efficient egg laying and defecation. Involved in axon regeneration [...] (1512 aa)
pll-1Phosphoinositide phospholipase C. (1075 aa)
plc-4Phosphoinositide phospholipase C. (751 aa)
plc-31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma plc-3; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) which plays an important role in the regulation of intracellular signaling cascades (Probable). Regulates basal and ovulatory sheath cell contractions by controlling Ca(2+) oscillations via IP3-mediated activation of IP3 receptor itr-1. In intestinal epithelial cells, regulates Ca(2+) oscillations which control posterior body wall muscle contractions required for defecation by IP3-mediated activation [...] (1350 aa)
gpcp-2Putative glycerophosphocholine phosphodiesterase GPCPD1 homolog 2. (796 aa)
T09B9.3Uncharacterized protein T09B9.3. (340 aa)
T12B3.3GP-PDE domain-containing protein. (356 aa)
T22G5.1GP-PDE domain-containing protein. (325 aa)
plc-2Phosphoinositide phospholipase C. (896 aa)
ZC155.4GP-PDE domain-containing protein. (375 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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