(3 nodes) Thiolase, active site network (Caenorhabditis elegans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B0303.3	Uncharacterized protein B0303.3; Belongs to the thiolase-like superfamily. Thiolase family. (448 aa)
	T02G5.7	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
	acaa-2	ACetyl-CoA Acyltransferase 2 homolog; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

Send network to Cytoscape

Export your current network:

... as a bitmap image:

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file format is 'PNG': portable network graphic

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0303.3	T02G5.7	B0303.3.2	T02G5.7.1	Uncharacterized protein B0303.3; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.934
B0303.3	acaa-2	B0303.3.2	F53A2.7.2	Uncharacterized protein B0303.3; Belongs to the thiolase-like superfamily. Thiolase family.	ACetyl-CoA Acyltransferase 2 homolog; Belongs to the thiolase-like superfamily. Thiolase family.	0.969
T02G5.7	B0303.3	T02G5.7.1	B0303.3.2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein B0303.3; Belongs to the thiolase-like superfamily. Thiolase family.	0.934
T02G5.7	acaa-2	T02G5.7.1	F53A2.7.2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	ACetyl-CoA Acyltransferase 2 homolog; Belongs to the thiolase-like superfamily. Thiolase family.	0.927
acaa-2	B0303.3	F53A2.7.2	B0303.3.2	ACetyl-CoA Acyltransferase 2 homolog; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein B0303.3; Belongs to the thiolase-like superfamily. Thiolase family.	0.969
acaa-2	T02G5.7	F53A2.7.2	T02G5.7.1	ACetyl-CoA Acyltransferase 2 homolog; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.927