node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
let-70 | ubc-1 | M7.1.1 | C35B1.1.1 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Mediates the selective degradation of short- lived and abnormal proteins. Plays a role in the DNA damage response. In particular, in response to ionizing radiation, associates with the E3 ubiquitin-protein ligase brc-1-brd-1 heterodimer on chromatin to activate E3-ubiquitin ligase activity of the heterodimer, and thus its DNA damage repair mechanisms ; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 1; Catalyzes the covalent attachment of ubiquitin to other proteins; Belongs to the ubiquitin-conjugating enzyme family. | 0.697 |
let-70 | ubc-13 | M7.1.1 | Y54G2A.31.1 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Mediates the selective degradation of short- lived and abnormal proteins. Plays a role in the DNA damage response. In particular, in response to ionizing radiation, associates with the E3 ubiquitin-protein ligase brc-1-brd-1 heterodimer on chromatin to activate E3-ubiquitin ligase activity of the heterodimer, and thus its DNA damage repair mechanisms ; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 13; Involved in protein ubiquitination, but has no ubiquitin ligase activity on its own. The uev-1-ubc-13 heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. Involved in sorting Lys-63-linked polyubiquitinated maternal membrane proteins for degradation by targeting to multivesicular bodies. May be involved in the ubiquitination and growth of intracellular polyglutamine protein aggregates. May have a role in AMPA-type glutamate receptor trafficking in neurons. | 0.589 |
let-70 | ubc-14 | M7.1.1 | Y87G2A.9.1 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Mediates the selective degradation of short- lived and abnormal proteins. Plays a role in the DNA damage response. In particular, in response to ionizing radiation, associates with the E3 ubiquitin-protein ligase brc-1-brd-1 heterodimer on chromatin to activate E3-ubiquitin ligase activity of the heterodimer, and thus its DNA damage repair mechanisms ; Belongs to the ubiquitin-conjugating enzyme family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.583 |
let-70 | ubc-20 | M7.1.1 | F40G9.3.1 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Mediates the selective degradation of short- lived and abnormal proteins. Plays a role in the DNA damage response. In particular, in response to ionizing radiation, associates with the E3 ubiquitin-protein ligase brc-1-brd-1 heterodimer on chromatin to activate E3-ubiquitin ligase activity of the heterodimer, and thus its DNA damage repair mechanisms ; Belongs to the ubiquitin-conjugating enzyme family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.813 |
let-70 | ubc-21 | M7.1.1 | C06E2.3.1 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Mediates the selective degradation of short- lived and abnormal proteins. Plays a role in the DNA damage response. In particular, in response to ionizing radiation, associates with the E3 ubiquitin-protein ligase brc-1-brd-1 heterodimer on chromatin to activate E3-ubiquitin ligase activity of the heterodimer, and thus its DNA damage repair mechanisms ; Belongs to the ubiquitin-conjugating enzyme family. | Probable ubiquitin-conjugating enzyme E2 21; Catalyzes the covalent attachment of ubiquitin to other proteins. | 0.427 |
let-70 | ubc-3 | M7.1.1 | Y71G12B.15a.2 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Mediates the selective degradation of short- lived and abnormal proteins. Plays a role in the DNA damage response. In particular, in response to ionizing radiation, associates with the E3 ubiquitin-protein ligase brc-1-brd-1 heterodimer on chromatin to activate E3-ubiquitin ligase activity of the heterodimer, and thus its DNA damage repair mechanisms ; Belongs to the ubiquitin-conjugating enzyme family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.608 |
let-70 | ubc-7 | M7.1.1 | F58A4.10.1 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Mediates the selective degradation of short- lived and abnormal proteins. Plays a role in the DNA damage response. In particular, in response to ionizing radiation, associates with the E3 ubiquitin-protein ligase brc-1-brd-1 heterodimer on chromatin to activate E3-ubiquitin ligase activity of the heterodimer, and thus its DNA damage repair mechanisms ; Belongs to the ubiquitin-conjugating enzyme family. | Probable ubiquitin-conjugating enzyme E2 7; Catalyzes the covalent attachment of ubiquitin to other proteins. | 0.620 |
let-70 | ubc-8 | M7.1.1 | Y94H6A.6.1 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Mediates the selective degradation of short- lived and abnormal proteins. Plays a role in the DNA damage response. In particular, in response to ionizing radiation, associates with the E3 ubiquitin-protein ligase brc-1-brd-1 heterodimer on chromatin to activate E3-ubiquitin ligase activity of the heterodimer, and thus its DNA damage repair mechanisms ; Belongs to the ubiquitin-conjugating enzyme family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.669 |
let-70 | ubc-9 | M7.1.1 | F29B9.6.2 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Mediates the selective degradation of short- lived and abnormal proteins. Plays a role in the DNA damage response. In particular, in response to ionizing radiation, associates with the E3 ubiquitin-protein ligase brc-1-brd-1 heterodimer on chromatin to activate E3-ubiquitin ligase activity of the heterodimer, and thus its DNA damage repair mechanisms ; Belongs to the ubiquitin-conjugating enzyme family. | SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like protein smo-1 from the aos-1-uba-2 E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase such as gei-17. Required to sumoylate the ETS transcription factor lin-1 and the Polycomb protein sop-2. Required for embryonic development, fertility, vulval morphogenesis and inhibition of vulval cell fates. Belongs to the ubiquitin-conjugating enzyme family. | 0.524 |
ubc-1 | let-70 | C35B1.1.1 | M7.1.1 | Ubiquitin-conjugating enzyme E2 1; Catalyzes the covalent attachment of ubiquitin to other proteins; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Mediates the selective degradation of short- lived and abnormal proteins. Plays a role in the DNA damage response. In particular, in response to ionizing radiation, associates with the E3 ubiquitin-protein ligase brc-1-brd-1 heterodimer on chromatin to activate E3-ubiquitin ligase activity of the heterodimer, and thus its DNA damage repair mechanisms ; Belongs to the ubiquitin-conjugating enzyme family. | 0.697 |
ubc-1 | ubc-12 | C35B1.1.1 | R09B3.4.1 | Ubiquitin-conjugating enzyme E2 1; Catalyzes the covalent attachment of ubiquitin to other proteins; Belongs to the ubiquitin-conjugating enzyme family. | NEDD8-conjugating enzyme ubc-12; Accepts the ubiquitin-like protein NEDD8 from the uba-3-ula-1 E1 complex and catalyzes its covalent attachment to other proteins. Plays a role in male tail tip morphogenesis. | 0.652 |
ubc-1 | ubc-13 | C35B1.1.1 | Y54G2A.31.1 | Ubiquitin-conjugating enzyme E2 1; Catalyzes the covalent attachment of ubiquitin to other proteins; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 13; Involved in protein ubiquitination, but has no ubiquitin ligase activity on its own. The uev-1-ubc-13 heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. Involved in sorting Lys-63-linked polyubiquitinated maternal membrane proteins for degradation by targeting to multivesicular bodies. May be involved in the ubiquitination and growth of intracellular polyglutamine protein aggregates. May have a role in AMPA-type glutamate receptor trafficking in neurons. | 0.962 |
ubc-1 | ubc-14 | C35B1.1.1 | Y87G2A.9.1 | Ubiquitin-conjugating enzyme E2 1; Catalyzes the covalent attachment of ubiquitin to other proteins; Belongs to the ubiquitin-conjugating enzyme family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.567 |
ubc-1 | ubc-20 | C35B1.1.1 | F40G9.3.1 | Ubiquitin-conjugating enzyme E2 1; Catalyzes the covalent attachment of ubiquitin to other proteins; Belongs to the ubiquitin-conjugating enzyme family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.613 |
ubc-1 | ubc-3 | C35B1.1.1 | Y71G12B.15a.2 | Ubiquitin-conjugating enzyme E2 1; Catalyzes the covalent attachment of ubiquitin to other proteins; Belongs to the ubiquitin-conjugating enzyme family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.630 |
ubc-1 | ubc-7 | C35B1.1.1 | F58A4.10.1 | Ubiquitin-conjugating enzyme E2 1; Catalyzes the covalent attachment of ubiquitin to other proteins; Belongs to the ubiquitin-conjugating enzyme family. | Probable ubiquitin-conjugating enzyme E2 7; Catalyzes the covalent attachment of ubiquitin to other proteins. | 0.615 |
ubc-1 | ubc-8 | C35B1.1.1 | Y94H6A.6.1 | Ubiquitin-conjugating enzyme E2 1; Catalyzes the covalent attachment of ubiquitin to other proteins; Belongs to the ubiquitin-conjugating enzyme family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.667 |
ubc-12 | ubc-1 | R09B3.4.1 | C35B1.1.1 | NEDD8-conjugating enzyme ubc-12; Accepts the ubiquitin-like protein NEDD8 from the uba-3-ula-1 E1 complex and catalyzes its covalent attachment to other proteins. Plays a role in male tail tip morphogenesis. | Ubiquitin-conjugating enzyme E2 1; Catalyzes the covalent attachment of ubiquitin to other proteins; Belongs to the ubiquitin-conjugating enzyme family. | 0.652 |
ubc-12 | ubc-13 | R09B3.4.1 | Y54G2A.31.1 | NEDD8-conjugating enzyme ubc-12; Accepts the ubiquitin-like protein NEDD8 from the uba-3-ula-1 E1 complex and catalyzes its covalent attachment to other proteins. Plays a role in male tail tip morphogenesis. | Ubiquitin-conjugating enzyme E2 13; Involved in protein ubiquitination, but has no ubiquitin ligase activity on its own. The uev-1-ubc-13 heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. Involved in sorting Lys-63-linked polyubiquitinated maternal membrane proteins for degradation by targeting to multivesicular bodies. May be involved in the ubiquitination and growth of intracellular polyglutamine protein aggregates. May have a role in AMPA-type glutamate receptor trafficking in neurons. | 0.623 |
ubc-12 | ubc-3 | R09B3.4.1 | Y71G12B.15a.2 | NEDD8-conjugating enzyme ubc-12; Accepts the ubiquitin-like protein NEDD8 from the uba-3-ula-1 E1 complex and catalyzes its covalent attachment to other proteins. Plays a role in male tail tip morphogenesis. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.553 |