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| | otub-4 | OTU domain-containing protein. (436 aa) |
| | C04E6.5 | USP domain-containing protein. (515 aa) |
| | clp-1 | Calpain clp-1; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates (By similarity). Required for assembly and maintenance of integrin attachment complexes which are essential for maintenance of adult muscle. Proteolytic activity is activated in response to increased intracellular Ca(2+) levels during cell degeneration and promotes necrotic cell death. (780 aa) |
| | ubh-4 | Ubiquitin carboxyl-terminal hydrolase ubh-4; Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C- terminal glycine of ubiquitin; Belongs to the peptidase C12 family. (321 aa) |
| | usp-14 | Ubiquitin carboxyl-terminal hydrolase 14; Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome (By similarity). Belongs to the peptidase C19 family. USP14/UBP6 subfamily. (489 aa) |
| | C17C3.13 | Uncharacterized protein. (179 aa) |
| | cpr-6 | Cathepsin B-like cysteine proteinase 6; Belongs to the peptidase C1 family. (379 aa) |
| | otub-1 | Ubiquitin thioesterase otubain-like; Hydrolase that can remove conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Specifically cleaves 'Lys-48'-linked polyubiquitin. (284 aa) |
| | C32B5.13 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (150 aa) |
| | C32B5.7 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (234 aa) |
| | C34F6.9 | USP domain-containing protein; Belongs to the peptidase C19 family. (1181 aa) |
| | ulp-4 | Ubiquitin-like protease 4; Protease required for deconjugation of smo-1 conjugates from target proteins which is necessary for cell cycle progression. Required for respiration and the maintenance of normal mitochondrial homeostasis. (382 aa) |
| | tag-329 | Uncharacterized protein; Belongs to the peptidase C1 family. (374 aa) |
| | cpr-1 | Gut-specific cysteine proteinase; Thiol protease. Has a role as a digestive enzyme. Belongs to the peptidase C1 family. (329 aa) |
| | usp-50 | USP domain-containing protein; Belongs to the peptidase C19 family. (811 aa) |
| | F07A11.4 | Ubiquitin carboxyl-terminal hydrolase. (1095 aa) |
| | usp-39 | Ubiquitin Specific Protease. (602 aa) |
| | F13A7.7 | Uncharacterized protein. (358 aa) |
| | F14D2.19 | Uncharacterized protein. (336 aa) |
| | F15D4.4 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (608 aa) |
| | otub-3 | OTU domain-containing protein. (330 aa) |
| | cdh-4 | Cadherin-4; Potential calcium-dependent cell-adhesion protein that controls axon guidance in the ventral cord. (4328 aa) |
| | F26E4.3 | Uncharacterized peptidase C1-like protein F26E4.3. (452 aa) |
| | usp-48 | Ubiquitin carboxyl-terminal hydrolase usp-48; Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin (By similarity). Involved in the processing of poly- ubiquitin precursors as well as that of ubiquitinated proteins (By similarity). Required post-developmentally to restrict the plasticity of epidermal cells, probably by regulating gene expression ; Belongs to the peptidase C19 family. (1262 aa) |
| | cpz-1 | Cathepsin Z-1; Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity). Plays an essential role in molting, a process during larval stages in which a new cuticle is formed and the old cuticle is shed. Probably, required for the degradation of the old cuticle. Belongs to the peptidase C1 family. (306 aa) |
| | F32H5.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (356 aa) |
| | F35B3.1 | USP domain-containing protein. (321 aa) |
| | cpr-2 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (326 aa) |
| | odr-8 | Ufm1-specific protease; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ufm-1, a ubiquitin-like modifier protein bound to a number of target proteins (By similarity). Required, with oct-4, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC. Operates in aggregation behavior, and responses to oxygen levels; Belongs to the peptidase C78 family. (589 aa) |
| | duo-1 | Deubiquitylating with USP/UBP and OTU domains; Belongs to the peptidase C19 family. (877 aa) |
| | cyld-1 | USP domain-containing protein. (1144 aa) |
| | tag-196 | Uncharacterized protein; Belongs to the peptidase C1 family. (477 aa) |
| | alh-11 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (687 aa) |
| | cpr-4 | Cathepsin B-like cysteine proteinase 4; Thiol protease which shows activity against the fluorogenic substrate z-Arg-Arg-AMC; Belongs to the peptidase C1 family. (335 aa) |
| | clp-8 | Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (646 aa) |
| | ubh-1 | Ubiquitin carboxyl-terminal hydrolase. (216 aa) |
| | clpr-2 | Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (502 aa) |
| | pcs-1 | Peptidase C83 domain-containing protein. (426 aa) |
| | png-1 | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta- aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native protein [...] (606 aa) |
| | F57F5.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (351 aa) |
| | F59E12.6 | USP domain-containing protein; Belongs to the peptidase C19 family. (499 aa) |
| | H12I13.1 | Ubiquitin carboxyl-terminal hydrolase. (910 aa) |
| | math-33 | Ubiquitin carboxyl-terminal hydrolase 7; Hydrolase that deubiquitinates target proteins. (1138 aa) |
| | clpr-3 | Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (308 aa) |
| | H34C03.2 | Ubiquitin carboxyl-terminal hydrolase. (980 aa) |
| | K02C4.3 | Probable ubiquitin carboxyl-terminal hydrolase K02C4.3. (1261 aa) |
| | ltd-1 | LIM zinc-binding domain-containing protein. (723 aa) |
| | K02E7.10 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (299 aa) |
| | ulp-5 | ULP_PROTEASE domain-containing protein. (311 aa) |
| | usp-33 | Ubiquitin carboxyl-terminal hydrolase. (716 aa) |
| | tra-3 | Calpain-5; Required for the correct female sexual development of the soma and germline in hermaphrodite animals, while being fully dispensable in males. Has calcium-dependent proteolytic activity and is involved in the cleavage of tra-2, for which it acts as a potentiator. Capable of calcium-dependent autolysis. Part of the necrosis cell death pathway. Required for necrosis of intestinal cells induced by B.thuringiensis endotoxin Cry6Aa ; Belongs to the peptidase C2 family. (648 aa) |
| | cpz-2 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (467 aa) |
| | R07E3.1 | Uncharacterized protein; Belongs to the peptidase C1 family. (402 aa) |
| | R09F10.1 | Uncharacterized protein; Belongs to the peptidase C1 family. (383 aa) |
| | usp-46 | Ubiquitin carboxyl-terminal hydrolase 46; Regulates the abundance of the glr-1 glutamate receptor in the ventral nerve cord by promoting its deubiquitination and preventing its degradation in the lysosome. Contributes to the regulation of embryonic polarity. (426 aa) |
| | cpl-1 | Cathepsin L-like; Cysteine protease which plays an essential role in the degradation of proteins in lysosomes. During early embryogenesis, maternally required for the proteolytic processing of yolk proteins in platelets, a lysosome- like structure where a slow and controlled degradation of yolk proteins occurs. In the gonad, required for the clearance of apoptotic germ cells in the engulfing cell phagolysosomes. In embryos, required for the degradation of endocytic and autophagic cargos. In embryos, may play a role in the degradation of lipid-containing droplets. Required for larval de [...] (337 aa) |
| | clp-2 | Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (805 aa) |
| | T05H10.1 | USP domain-containing protein; Belongs to the peptidase C19 family. (1326 aa) |
| | ulp-1 | Sentrin-specific protease; Protease that deconjugates smo-1 from targeted proteins and may catalyze the processing of smo-1 to its mature form. (697 aa) |
| | cpr-3 | Cathepsin B-like cysteine proteinase 3; Belongs to the peptidase C1 family. (370 aa) |
| | clp-9 | Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (718 aa) |
| | T22F3.2 | USP domain-containing protein. (393 aa) |
| | T24B8.7 | Ubiquitin carboxyl-terminal hydrolase; Belongs to the peptidase C19 family. (2938 aa) |
| | usp-5 | Ubiquitin carboxyl-terminal hydrolase. (789 aa) |
| | clpr-1 | Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (252 aa) |
| | clp-10 | Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (634 aa) |
| | cpr-8 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (335 aa) |
| | W07B8.4 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (335 aa) |
| | cpr-5 | Cathepsin B-like cysteine proteinase 5; Belongs to the peptidase C1 family. (344 aa) |
| | duo-3 | Deubiquitylating with USP/UBP and OTU domains. (924 aa) |
| | Y113G7B.15 | Uncharacterized protein; Belongs to the peptidase C1 family. (362 aa) |
| | ulp-2 | Ubiquitin-like protease 2; Protease that catalyzes two essential functions in the smo-1 pathway: processing of full-length smo-1 to their mature forms and deconjugation of smo-1 from targeted proteins (By similarity). May deconjugate smo-1 from the cadherin protein hmr-1 and plays a role in its recruitment to and the maintenance of adherens junctions. Required for epidermal morphogenesis during embryonic development ; Belongs to the peptidase C48 family. (893 aa) |
| | clp-4 | Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (716 aa) |
| | ubh-3 | Ubiquitin carboxyl-terminal hydrolase. (227 aa) |
| | ubh-2 | Ubiquitin carboxyl-terminal hydrolase. (227 aa) |
| | Y40H7A.10 | Uncharacterized protein; Belongs to the peptidase C1 family. (343 aa) |
| | clp-3 | Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (752 aa) |
| | ulp-3 | ULP_PROTEASE domain-containing protein. (210 aa) |
| | Y51A2D.1 | Uncharacterized protein; Belongs to the peptidase C1 family. (314 aa) |
| | Y51A2D.8 | Uncharacterized protein; Belongs to the peptidase C1 family. (386 aa) |
| | Y65B4A.2 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (448 aa) |
| | Y67D2.2 | Ubiquitin carboxyl-terminal hydrolase. (474 aa) |
| | usp-3 | Ubiquitin carboxyl-terminal hydrolase. (550 aa) |
| | Y71H2AM.25 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (299 aa) |
| | Y71H2AR.2 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (345 aa) |
| | xpc-1 | XPC (Xeroderma Pigmentosum group C) DNA repair gene homolog. (1119 aa) |
| | clp-6 | Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (627 aa) |
| | clp-7 | Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (778 aa) |
| | atg-4.1 | Cysteine protease atg-4.1; Cysteine protease required for autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins lgg-1, to reveal a C-terminal glycine (Probable). Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy (Probable). Its cleavage activity is functionally redundant to atg-4.2, but it cleaves lgg-1 precursors more efficiently than atg-4.2 (Probable). Acts redundantly with atg-4.2 to promote the lgg-1 delipidation to release the protein fro [...] (481 aa) |
| | cyk-3 | Ubiquitin carboxyl-terminal hydrolase cyk-3; Ubiquitin-protein hydrolase which cleaves ubiquitin from ubiquitinated proteins. Plays a role in embryo osmoregulation. Probably by regulating osmosis, controls actin redistribution in the 1-cell embryos and thus actin-dependent processes such as cytokinesis and P-granules segregation. During the first embryonic mitotic division, involved in the formation of a functional microtubule organizing center provided by the male pronucleus ; Belongs to the peptidase C19 family. (1178 aa) |
| | atg-4.2 | Cysteine protease atg-4.2; Cysteine protease required for autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins lgg-1, to reveal a C-terminal glycine (Probable). Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy (Probable). Its cleavage activity is functionally redundant to atg-4.1, but it cleaves lgg-1 precursors less efficiently than atg-4.1 (Probable). In contrast to atg-4.1, plays a more significant role in the later phases of autophagy and [...] (521 aa) |
