node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bli-3 | gpx-1 | F56C11.1.1 | F26E4.12.1 | Dual oxidase 1; Plays a role in cuticle biogenesis. In complex with doxa-1 and tsp-15, produces reactive oxygen species (ROS), which are probably used by mlt-7 for tyrosine cross-linking, thus stabilizing cuticular extracellular matrix. May regulate the production of ROS by playing a role in modulating proline catabolism. Required in combination with mlt-7 for correct formation of cross-links in cuticle collagens. Association with the GTPase rho-1 promotes ROS production and this interaction may be modulated by memo-1, in order to control the oxidative stress response and longevity. In [...] | Glutathione peroxidase 1; May constitute a glutathione peroxidase-like protective system against oxidative stresses. | 0.407 |
bli-3 | mlt-7 | F56C11.1.1 | ZK430.8.1 | Dual oxidase 1; Plays a role in cuticle biogenesis. In complex with doxa-1 and tsp-15, produces reactive oxygen species (ROS), which are probably used by mlt-7 for tyrosine cross-linking, thus stabilizing cuticular extracellular matrix. May regulate the production of ROS by playing a role in modulating proline catabolism. Required in combination with mlt-7 for correct formation of cross-links in cuticle collagens. Association with the GTPase rho-1 promotes ROS production and this interaction may be modulated by memo-1, in order to control the oxidative stress response and longevity. In [...] | Peroxidase mlt-7 heavy chain; Plays an essential role in cuticle biogenesis. Required in combination with bli-3 for correct formation of cross-links in cuticle collagens. | 0.463 |
ctl-1 | ctl-2 | Y54G11A.6.2 | Y54G11A.5.2 | Catalase-2; Catalase involved in the oxidative stress response serving to protect cells from toxicity (Probable). For instance plays a role in defending against oxidative damage induced by excessive copper stress. Not required for maintaining normal lifespan. | Peroxisomal catalase 1; Peroxisomal catalase involved in the oxidative stress response serving to protect cells from toxicity. Plays a role in maintaining normal lifespan. Plays a role in regulating the response to pathogens such as E.faecalis. | 0.948 |
ctl-1 | ctl-3 | Y54G11A.6.2 | Y54G11A.13a.1 | Catalase-2; Catalase involved in the oxidative stress response serving to protect cells from toxicity (Probable). For instance plays a role in defending against oxidative damage induced by excessive copper stress. Not required for maintaining normal lifespan. | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. | 0.906 |
ctl-1 | gpx-1 | Y54G11A.6.2 | F26E4.12.1 | Catalase-2; Catalase involved in the oxidative stress response serving to protect cells from toxicity (Probable). For instance plays a role in defending against oxidative damage induced by excessive copper stress. Not required for maintaining normal lifespan. | Glutathione peroxidase 1; May constitute a glutathione peroxidase-like protective system against oxidative stresses. | 0.583 |
ctl-1 | gpx-2 | Y54G11A.6.2 | R05H10.5b.1 | Catalase-2; Catalase involved in the oxidative stress response serving to protect cells from toxicity (Probable). For instance plays a role in defending against oxidative damage induced by excessive copper stress. Not required for maintaining normal lifespan. | Glutathione peroxidase 2; May constitute a glutathione peroxidase-like protective system against oxidative stresses. | 0.658 |
ctl-1 | gpx-3 | Y54G11A.6.2 | C11E4.2.1 | Catalase-2; Catalase involved in the oxidative stress response serving to protect cells from toxicity (Probable). For instance plays a role in defending against oxidative damage induced by excessive copper stress. Not required for maintaining normal lifespan. | Glutathione peroxidase 3; Belongs to the glutathione peroxidase family. | 0.579 |
ctl-1 | gpx-4 | Y54G11A.6.2 | Y94H6A.4.1 | Catalase-2; Catalase involved in the oxidative stress response serving to protect cells from toxicity (Probable). For instance plays a role in defending against oxidative damage induced by excessive copper stress. Not required for maintaining normal lifespan. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.577 |
ctl-1 | gpx-5 | Y54G11A.6.2 | C11E4.1.1 | Catalase-2; Catalase involved in the oxidative stress response serving to protect cells from toxicity (Probable). For instance plays a role in defending against oxidative damage induced by excessive copper stress. Not required for maintaining normal lifespan. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.616 |
ctl-1 | gpx-6 | Y54G11A.6.2 | T09A12.2b.1 | Catalase-2; Catalase involved in the oxidative stress response serving to protect cells from toxicity (Probable). For instance plays a role in defending against oxidative damage induced by excessive copper stress. Not required for maintaining normal lifespan. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.658 |
ctl-1 | gpx-7 | Y54G11A.6.2 | R03G5.5a.1 | Catalase-2; Catalase involved in the oxidative stress response serving to protect cells from toxicity (Probable). For instance plays a role in defending against oxidative damage induced by excessive copper stress. Not required for maintaining normal lifespan. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.592 |
ctl-1 | gpx-8 | Y54G11A.6.2 | F55A3.5.1 | Catalase-2; Catalase involved in the oxidative stress response serving to protect cells from toxicity (Probable). For instance plays a role in defending against oxidative damage induced by excessive copper stress. Not required for maintaining normal lifespan. | Glutathione PeroXidase. | 0.599 |
ctl-1 | prdx-3 | Y54G11A.6.2 | R07E5.2.1 | Catalase-2; Catalase involved in the oxidative stress response serving to protect cells from toxicity (Probable). For instance plays a role in defending against oxidative damage induced by excessive copper stress. Not required for maintaining normal lifespan. | Probable peroxiredoxin prdx-3; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.755 |
ctl-2 | ctl-1 | Y54G11A.5.2 | Y54G11A.6.2 | Peroxisomal catalase 1; Peroxisomal catalase involved in the oxidative stress response serving to protect cells from toxicity. Plays a role in maintaining normal lifespan. Plays a role in regulating the response to pathogens such as E.faecalis. | Catalase-2; Catalase involved in the oxidative stress response serving to protect cells from toxicity (Probable). For instance plays a role in defending against oxidative damage induced by excessive copper stress. Not required for maintaining normal lifespan. | 0.948 |
ctl-2 | ctl-3 | Y54G11A.5.2 | Y54G11A.13a.1 | Peroxisomal catalase 1; Peroxisomal catalase involved in the oxidative stress response serving to protect cells from toxicity. Plays a role in maintaining normal lifespan. Plays a role in regulating the response to pathogens such as E.faecalis. | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. | 0.902 |
ctl-2 | gpx-1 | Y54G11A.5.2 | F26E4.12.1 | Peroxisomal catalase 1; Peroxisomal catalase involved in the oxidative stress response serving to protect cells from toxicity. Plays a role in maintaining normal lifespan. Plays a role in regulating the response to pathogens such as E.faecalis. | Glutathione peroxidase 1; May constitute a glutathione peroxidase-like protective system against oxidative stresses. | 0.760 |
ctl-2 | gpx-2 | Y54G11A.5.2 | R05H10.5b.1 | Peroxisomal catalase 1; Peroxisomal catalase involved in the oxidative stress response serving to protect cells from toxicity. Plays a role in maintaining normal lifespan. Plays a role in regulating the response to pathogens such as E.faecalis. | Glutathione peroxidase 2; May constitute a glutathione peroxidase-like protective system against oxidative stresses. | 0.700 |
ctl-2 | gpx-3 | Y54G11A.5.2 | C11E4.2.1 | Peroxisomal catalase 1; Peroxisomal catalase involved in the oxidative stress response serving to protect cells from toxicity. Plays a role in maintaining normal lifespan. Plays a role in regulating the response to pathogens such as E.faecalis. | Glutathione peroxidase 3; Belongs to the glutathione peroxidase family. | 0.597 |
ctl-2 | gpx-4 | Y54G11A.5.2 | Y94H6A.4.1 | Peroxisomal catalase 1; Peroxisomal catalase involved in the oxidative stress response serving to protect cells from toxicity. Plays a role in maintaining normal lifespan. Plays a role in regulating the response to pathogens such as E.faecalis. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.579 |
ctl-2 | gpx-5 | Y54G11A.5.2 | C11E4.1.1 | Peroxisomal catalase 1; Peroxisomal catalase involved in the oxidative stress response serving to protect cells from toxicity. Plays a role in maintaining normal lifespan. Plays a role in regulating the response to pathogens such as E.faecalis. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.698 |