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| | acr-2 | Acetylcholine receptor subunit beta-type acr-2; Non-alpha subunit of nicotinic acetylcholine receptor (nAChR). Acts in cholinergic motoneurons to regulate presynaptic neurotransmitter release, thereby ensuring normal level of excitation of cholinergic motoneurons during locomotion. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. (575 aa) |
| | lgc-49 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa) |
| | glr-3 | GLutamate Receptor family (AMPA). (836 aa) |
| | cmk-1 | Calcium/calmodulin-dependent protein kinase type 1; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade which results in transcriptional activation. Transcriptional activation occurs at least in part through phosphorylation of crh-1. Regulates gene expression, sensory morphology, and function of the AFD thermosensory neurons. Involved in long-term adaptation of AFD neurons to temperatures warmer than the initial acclimatized cultivation temperature. Acts in the FLP thermal nociceptors to moderate the responsiveness to noxious [...] (348 aa) |
| | mod-1 | Serotonin-gated chloride channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (489 aa) |
| | acr-5 | Acetylcholine receptor subunit alpha-type acr-5; Possible acetylcholine receptor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. (598 aa) |
| | ncs-3 | Neuronal Calcium Sensor family. (199 aa) |
| | deg-3 | Acetylcholine receptor subunit alpha-type deg-3; Subunit of the non-synaptic neuronal acetylcholine receptor, which may play a role in chemotaxis towards choline. After binding choline or acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion- conducting channel across the plasma membrane ; Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. (564 aa) |
| | gpc-1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (62 aa) |
| | exp-1 | Gamma-aminobutyric acid receptor exp-1; GABA receptor that functions as an excitatory cation channel. Permeable to monovalent cations such as Na(+) and K(+). Has negligible divalent cation permeability. Does not act as a chloride channel. Mediates enteric muscle contractions required for defecation. Probably by regulating the defecation motor program, required for fatty acid uptake by intestinal cells. (539 aa) |
| | lin-33 | Uncharacterized protein. (243 aa) |
| | nsf-1 | Vesicle-fusing ATPase; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity); Belongs to the AAA ATPase family. (824 aa) |
| | F59E12.8 | Uncharacterized protein. (412 aa) |
| | acr-23 | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. (545 aa) |
| | lgc-30 | Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (529 aa) |
| | acc-1 | Acetylcholine-gated chloride channel subunit acc-1; Acetylcholine-gated chloride channel subunit. Forms functional homopentameric (in vitro) and functional heteropentameric ion channels with acc-3 and acc-4 ion channel subunits. Currents in channels are triggered in response to acetylcholine, but not in response to GABA, glutamate, glycine, histamine or dopamine. (470 aa) |
| | acc-3 | Acetylcholine-gated chloride channel subunit acc-3; Probable acetylcholine-gated chloride channel regulatory subunit. Does not have ion channel activity alone as a homopentamer, but forms a functional heteropentameric ion channel with acc-1. Belongs to the ligand-gated ion channel (TC 1.A.9) family. (517 aa) |
| | acr-17 | AcetylCholine Receptor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (515 aa) |
| | gpb-2 | Guanine nucleotide-binding protein subunit beta-2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (369 aa) |
| | lgc-11 | Acetylcholine receptor (51.1 kD) (Acr-22); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (434 aa) |
| | F47F2.1 | cAMP-dependent protein kinase, catalytic subunit-like; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. cAMP subfamily. (398 aa) |
| | lgc-47 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (428 aa) |
| | lgc-44 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (618 aa) |
| | glr-6 | PBPe domain-containing protein. (844 aa) |
| | F39B2.8 | G_PROTEIN_RECEP_F3_4 domain-containing protein. (594 aa) |
| | F32D8.1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa) |
| | acr-18 | AcetylCholine Receptor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (510 aa) |
| | acr-21 | AcetylCholine Receptor. (635 aa) |
| | acr-15 | AcetylCholine Receptor. (479 aa) |
| | acr-16 | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. (498 aa) |
| | glc-2 | Glutamate-gated chloride channel subunit beta; Glutamate-gated chloride channel subunit; channel properties depend on the subunit composition. Glutamate binding triggers a rapidly reversible current in heteromeric channels formed by glc-1 and glc-2, while the anti-helmintic drug ivermectin and other avermectins trigger a permanently open channel configuration. Channels containing only glc- 2 are activated by glutamate, but not by ivermectin (in vitro). The heteromeric channel formed by glc-1 and glc-2 is also activated by ibotenate, and it is blocked by picrotoxin and flufenamic acid. (434 aa) |
| | glr-8 | Lig_chan-Glu_bd domain-containing protein. (547 aa) |
| | unc-38 | Acetylcholine receptor subunit alpha-type unc-38; Alpha subunit of nicotinic acetylcholine receptor (nAChR). Probably acts in cholinergic motoneurons to regulate presynaptic neurotransmitter release, thereby ensuring normal level of excitation of cholinergic motoneurons during locomotion. Involved in nAChR sensitivity to nicotine. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. (511 aa) |
| | lgc-31 | Neur_chan_memb domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (675 aa) |
| | lgc-4 | Ligand-gated ion channel 4; Possible acetylcholine receptor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (635 aa) |
| | lgc-6 | Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (425 aa) |
| | lgc-5 | Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (433 aa) |
| | acy-1 | Adenylyl CYclase. (1253 aa) |
| | lgc-22 | ShKT domain-containing protein. (445 aa) |
| | gpb-1 | Guanine nucleotide-binding protein subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. In the early embryo, controls the magnitude of the forces acting on centrosomes but is not required for generating asymmetric forces. (340 aa) |
| | lgc-51 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (450 aa) |
| | lgc-38 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (479 aa) |
| | glc-1 | Glutamate-gated chloride channel alpha; Glutamate-gated chloride channel subunit; channel properties depend on the subunit composition. Glutamate binding triggers a rapidly reversible current in heteromeric channels formed by glc-1 and glc-2, while the anti-helmintic drug ivermectin and other avermectins trigger a permanently open channel configuration. Channels containing only glc- 1 are activated by ivermectin, but not by glutamate alone (in vitro). The heteromeric channel formed by glc-1 and glc-2 is also activated by ibotenate, and it is blocked by picrotoxin and flufenamic acid. P [...] (461 aa) |
| | ncs-2 | Neuronal calcium sensor 2; Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner; Belongs to the recoverin family. (190 aa) |
| | sel-2 | Putative neurobeachin homolog; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity). Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells. (2507 aa) |
| | lgc-39 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (563 aa) |
| | lev-1 | Acetylcholine receptor subunit beta-type lev-1; Non-alpha subunit of nicotinic acetylcholine receptor (nAChR). Involved in nAChR sensitivity to nicotine. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. (507 aa) |
| | ggr-3 | GABA/Glycine Receptor family (See gbr); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (445 aa) |
| | gpc-2 | G protein gamma domain-containing protein. (62 aa) |
| | nmr-1 | NMDA-type ionotropic glutamate receptor NMR-1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1025 aa) |
| | lgc-36 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (536 aa) |
| | aps-2 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa) |
| | pkc-2 | Protein kinase C-like 2; PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (936 aa) |
| | acr-11 | AcetylCholine Receptor. (461 aa) |
| | lgc-28 | Neur_chan_LBD domain-containing protein. (397 aa) |
| | acc-2 | Acetylcholine-gated chloride channel subunit acc-2; Acetylcholine-gated chloride channel subunit. Currents in channels are triggered in response to acetylcholine. Channel properties may be modulated by the formation of homomeric and heteromeric channels. (445 aa) |
| | C50F4.9 | Uncharacterized protein. (127 aa) |
| | lgc-48 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (366 aa) |
| | ggr-2 | GABA/Glycine Receptor family (See gbr); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (546 aa) |
| | acy-3 | Adenylyl CYclase. (1243 aa) |
| | ncs-1 | Neuronal calcium sensor 1; Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Can substitute for calmodulin and directly activate PDE, NO synthase, and calcineurin. Regulates associative learning and memory in a calcium dependent manner. (191 aa) |
| | glr-7 | GLutamate Receptor family (AMPA); Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (885 aa) |
| | lgc-43 | Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (679 aa) |
| | acr-9 | AcetylCholine Receptor. (534 aa) |
| | lgc-41 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (564 aa) |
| | lev-8 | Uncharacterized protein. (531 aa) |
| | lgc-21 | Neur_chan_LBD domain-containing protein. (462 aa) |
| | acr-19 | AcetylCholine Receptor. (560 aa) |
| | glc-4 | Glutamate-gated ChLoride channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (500 aa) |
| | dlg-1 | Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family. (967 aa) |
| | lgc-24 | Neur_chan_LBD domain-containing protein. (389 aa) |
| | lgc-23 | Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (403 aa) |
| | acy-2 | Adenylyl CYclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1080 aa) |
| | ggr-1 | Glycine receptor subunit beta-type 4; Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Contributes to the generation of inhibitory postsynaptic currents. (473 aa) |
| | C08B6.5 | Uncharacterized protein. (423 aa) |
| | glr-1 | Glutamate receptor 1; Non-NMDA (N-methyl-D-aspartate) ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of glutamate are mediated by a variety of receptors that are named according to their selective agonists. May contribute to a sensory discrimination between mechanical and chemical stimuli. Plays a role in controlling movement in response to environmental cues such as food availability and mechanosensory stimulation such as the nose touch response. In AIB interneurons, promotes om [...] (962 aa) |
| | glr-4 | GLutamate Receptor family (AMPA). (951 aa) |
| | ckk-1 | Calcium/calmodulin-dependent protein kinase kinase; Calcium/calmodulin-dependent protein kinase which phosphorylates cmk-1. Component of a calcium-triggered signaling cascade involved in CRE-mediated transcriptional activation, probably through cmk-1-mediated crh-1/CREB phosphorylation. (541 aa) |
| | lgc-9 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa) |
| | cup-4 | Acetylcholine receptor-like protein cup-4; Thought to regulate endocytosis in coelomocytes through modulation of phospholipase C activity. Possible acetylcholine receptor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. (433 aa) |
| | lgc-20 | Neur_chan_LBD domain-containing protein. (454 aa) |
| | glr-2 | Glutamate receptor 2; L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of glutamate are mediated by a variety of receptors that are named according to their selective agonists. Required for response to mechanical and osmotic stimuli; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (977 aa) |
| | avr-14 | Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (430 aa) |
| | lgc-25 | Neur_chan_LBD domain-containing protein. (502 aa) |
| | irk-1 | Inward rectifier potassium channel irk-1; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Required for modulation of the activity of the hermaphrodite-specific neurons (HSNs) by the G-protein coupled neuropeptide receptor egl-6 which in turn controls egg-laying behavior. (544 aa) |
| | R06A10.4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | acr-20 | AcetylCholine Receptor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (556 aa) |
| | kin-2 | cAMP-dependent protein kinase regulatory subunit; Controls the rhythmic contraction of enteric muscles probably by regulating G-protein coupled receptor aex-2-mediated calcium influx in GABAergic DVB neurons; Belongs to the cAMP-dependent kinase regulatory chain family. (376 aa) |
| | avr-15 | Neur_chan_memb domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (657 aa) |
| | lgc-12 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (428 aa) |
| | dpy-23 | AP-2 complex subunit mu; Component of the adaptor complexes which link clathrin to receptors in coated vesicles (By similarity). Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity). AP50 is a subunit of the plasma membrane adaptor (By similarity). Essential wnt/egl-20 signaling protein that functions in wnt/egl-20-producing cells. Required for the AP-2 complex-mediated endocytosis of membrane proteins including wntless homolog mig-14 in egl-20-producing cells. During [...] (441 aa) |
| | acy-4 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1013 aa) |
| | nmr-2 | NMDA-type ionotropic glutamate receptor NMR-2. (990 aa) |
| | lgc-13 | Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (399 aa) |
| | lgc-14 | Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (400 aa) |
| | lgc-15 | Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (399 aa) |
| | lgc-16 | Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (401 aa) |
| | lgc-17 | Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (401 aa) |
| | lgc-18 | Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (399 aa) |
| | rskn-1 | Putative ribosomal protein S6 kinase alpha-1; Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of transcription (By similarity). Suppresses germline tumor formation by preventing the dedifferentiation of secondary spermatocytes probably downstream of mpk-1 ; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (804 aa) |
| | lgc-1 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (371 aa) |
| | acr-14 | AcetylCholine Receptor. (500 aa) |
| | unc-29 | Acetylcholine receptor subunit beta-type unc-29; Non-alpha subunit of nicotinic acetylcholine receptor (nAChR). Involved in nAChR sensitivity to nicotine and levasimole. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. (493 aa) |
| | acr-7 | Acetylcholine receptor subunit alpha-type acr-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. (538 aa) |
| | lgc-54 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (493 aa) |
| | fem-2 | Protein phosphatase fem-2; Dephosphorylates auto-phosphorylated Ca(2+)/calmodulin- dependent protein kinase unc-43/CAMKII in vitro. Involved in the regulation of sex determination. Together with fem-3, required for male sexual development by promoting the proteasomal-mediated degradation of tra-1, a transcription repressor of male-specific genes. Promotes apoptosis. Belongs to the PP2C family. (449 aa) |
| | lgc-32 | Neur_chan_LBD domain-containing protein. (390 aa) |
| | lgc-50 | Ligand-gated ion channel 50. (491 aa) |
| | apa-2 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (925 aa) |
| | unc-49 | Ionotropic GABA receptor subunit UNC-49B.3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (506 aa) |
| | lgc-53 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa) |
| | lgc-40 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (494 aa) |
| | T25E4.2 | Uncharacterized protein T25E4.2. (471 aa) |
| | T26C5.2 | Uncharacterized protein. (595 aa) |
| | des-2 | Acetylcholine receptor subunit alpha-type des-2; Subunit of the non-synaptic neuronal acetylcholine receptor (AChR), which may play a role in chemotaxis towards choline. After binding choline or acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. (559 aa) |
| | lgc-34 | Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (390 aa) |
| | acc-4 | Acetylcholine-gated ion channel acc-4; Probable acetylcholine-gated chloride channel subunit. Does not have ion channel activity alone as a homopentamer, but forms a functional heteropentameric ion channel with acc-1. May function with lgc-46 to regulate synaptic transmission and synaptic vesicle release in response to acetylcholine in cholinergic motor neurons. (408 aa) |
| | W02A2.5 | Uncharacterized protein. (487 aa) |
| | lgc-45 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (1046 aa) |
| | lgc-19 | Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (400 aa) |
| | unc-63 | Acetylcholine receptor subunit alpha-type unc-63; Alpha subunit of nicotinic acetylcholine receptor (nAChR). Probably acts in cholinergic motoneurons to regulate presynaptic neurotransmitter release, thereby ensuring normal level of excitation of cholinergic motoneurons during locomotion. Involved in nAChR sensitivity to nicotine and levamisole. (502 aa) |
| | lgc-55 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (538 aa) |
| | flh-1 | FLYWCH-type domain-containing protein. (507 aa) |
| | flh-3 | FLYWCH-type domain-containing protein. (420 aa) |
| | lgc-42 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (412 aa) |
| | gbb-1 | Gamma-aminobutyric acid type B receptor subunit 1; Component of a heterodimeric G-protein coupled receptor for GABA, formed by gbb-1 and gbb-2 (By similarity). Within the heterodimeric GABA receptor, only gbb-1 seems to bind agonists, while gbb-2 mediates coupling to G proteins (By similarity). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase (By similarity). Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates po [...] (899 aa) |
| | lgc-29 | Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (398 aa) |
| | lgc-35 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (515 aa) |
| | eat-2 | Neuronal acetylcholine receptor subunit eat-2; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). Nicotinic acetylcholine receptor in the MC pharyngeal motor neuron involved in pharyngeal pumping. Has a role in the determination of life span possibly via calorific restriction which affects growth rate, although this is independent of metabolic activity. Plays a role in the defense against the accumulation of ingested live pathogenic [...] (474 aa) |
| | lgc-7 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (439 aa) |
| | Y57G11C.22 | Uncharacterized protein. (444 aa) |
| | lgc-8 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (438 aa) |
| | lgc-26 | Neur_chan_LBD domain-containing protein. (486 aa) |
| | lgc-46 | Probable ligand-gated ion channel 46; Probable component of a ligand-gated anion channel. Negatively regulates synaptic transmission and synaptic vesicle release in response to acetylcholine in cholinergic motor neurons. Role in synaptic vesicle release kinetics may be in association with the ligand-gated ion channel protein acc-4. (508 aa) |
| | lgc-10 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (450 aa) |
| | acr-25 | AcetylCholine Receptor. (544 aa) |
| | lgc-52 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (423 aa) |
| | acr-24 | AcetylCholine Receptor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (578 aa) |
| | lgc-27 | Neur_chan_LBD domain-containing protein. (428 aa) |
| | zyg-8 | Serine/threonine-protein kinase zyg-8; Plays a role in spindle positioning during asymmetric division of one-cell stage embryos. Affects spindle position by promoting microtubule assembly during anaphase. (802 aa) |
| | Y94H6A.12 | Uncharacterized protein. (120 aa) |
| | Y94H6A.7 | LMWPc domain-containing protein. (164 aa) |
| | glr-5 | GLutamate Receptor family (AMPA). (932 aa) |
| | glc-3 | Glutamate-gated chloride channel subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (484 aa) |
| | ztf-8 | Zinc finger putative Transcription Factor family. (687 aa) |
| | gab-1 | Gamma-aminobutyric acid receptor subunit beta; GABA, an inhibitory neurotransmitter, mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. (550 aa) |
| | lgc-37 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (483 aa) |
| | acr-8 | Acetylcholine receptor 8. (537 aa) |
| | gbb-2 | Gamma-aminobutyric acid type B receptor subunit 2; Component of a heterodimeric G-protein coupled receptor for GABA, formed by gbb-1 and gbb-2 (By similarity). Within the heterodimeric GABA receptor, only gbb-1 seems to bind agonists, while gbb-2 mediates coupling to G proteins (By similarity). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase (By similarity). Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates po [...] (842 aa) |
| | ZK867.2 | Lig_chan-Glu_bd domain-containing protein. (354 aa) |
| | kin-1 | cAMP-dependent protein kinase catalytic subunit; Essential for larval development. Controls the rhythmic contraction of enteric muscles probably by regulating G- protein coupled receptor aex-2-mediated calcium influx in GABAergic DVB neurons. Plays a role in the control of oocyte meiotic maturation by gonadal sheath cells. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (579 aa) |
| | acr-6 | AcetylCholine Receptor. (551 aa) |
| | acr-10 | AcetylCholine Receptor. (557 aa) |
| | acr-12 | Nicotinic acetylcholine receptor-like subunit ACR-12. (573 aa) |
| | irk-2 | Inward Rectifying K (Potassium) channel family. (497 aa) |
| | acr-3 | Acetylcholine receptor subunit beta-type acr-3; Non-alpha subunit of nicotinic acetylcholine receptor (nAChR). Probably acts in cholinergic motoneurons to regulate presynaptic neurotransmitter release, thereby ensuring normal level of excitation of cholinergic motoneurons during locomotion. (487 aa) |
| | unc-43 | Calcium/calmodulin-dependent protein kinase type II; Acts in the signaling of a variety of pathways and processes. Phosphorylates 'Ser-319' of daf-16 in response to stress signals, such as heat, starvation and oxidation, which plays a role in prolonging lifespan. Required for viability under chronic osmotic stress in which it acts downstream of osr-1. Has roles in locomotion, oocyte maturation, brood size, egg laying, defecation, meiotic maturation and neuronal cell fate specification. Required for the regulation of synaptic density and neuromuscular junction morphology. Regulates the [...] (681 aa) |
