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such-1 | Suppressor of spindle checkpoint defect 1; Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (By similarity). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (By similarity). Required for the metaphase to anaphase transition in meiosis. Plays a role in the segregation of DNA and centrioles during meiosis in male germ cells. Belongs to the APC5 family. (798 aa) | ||||
mdf-2 | HORMA domain-containing protein. (203 aa) | ||||
ubq-2 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] (128 aa) | ||||
fzr-1 | WD_REPEATS_REGION domain-containing protein. (702 aa) | ||||
fzy-1 | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. (507 aa) | ||||
madf-11 | MADF domain-containing protein. (516 aa) | ||||
skr-17 | SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family. (180 aa) | ||||
apc-17 | Anaphase Promoting Complex see also mat. (325 aa) | ||||
kxd-1 | KxDL domain-containing protein. (140 aa) | ||||
skr-16 | SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family. (181 aa) | ||||
skr-12 | SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family. (172 aa) | ||||
skr-9 | SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family. (194 aa) | ||||
skr-13 | SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family. (172 aa) | ||||
skr-8 | SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family. (194 aa) | ||||
cul-1 | Cullin-1; Probable core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required for developmentally programmed transitions from the G1 phase of the cell cycle to the G0 phase or the apoptotic pathway. (780 aa) | ||||
F08F1.9 | CYCLIN domain-containing protein; Belongs to the cyclin family. (130 aa) | ||||
emb-27 | Cell division cycle protein 16 homolog; Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (By similarity). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (By similarity). Developmental role in early embryogenesis and the metaphase to anaphase transition in oocyte and spermatocyte meiosis and mitosis in germ cells. Required for embryonic anterior-posterior axis formation. Plays a role in regulating [...] (655 aa) | ||||
mat-3 | Cell division cycle protein 23 homolog; Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins. Developmental role in early embryogenesis and the metaphase to anaphase transition in oocyte and spermatocyte meiosis and mitosis in germ cells. Required for embryonic anterior-posterior axis formation. Plays a role in regulating the abundance of glr-1 receptor [...] (673 aa) | ||||
apc-10 | Anaphase-promoting complex subunit 10; Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins. (212 aa) | ||||
ubq-1 | Ubiquitin-related; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degrad [...] (838 aa) | ||||
F34H10.1 | Probable ribosomal protein F34H10.1; Belongs to the eukaryotic ribosomal protein eS31 family. (142 aa) | ||||
apc-11 | Anaphase-promoting complex subunit 11; Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins. Developmental role in early embryogenesis and the metaphase to anaphase transition in meiosis and mitosis. In vitro, recruits the ubiquitin-conjugating enzyme ubc-2 to exert ubiquitin ligase activity. Belongs to the RING-box family. (135 aa) | ||||
mig-38 | Abnormal cell migration protein 38; During gonad development, involved in distal tip cell (DTC) migration from the dorsal side of the hermaphrodite body to the midbody which allows for the formation of gonad arms. Role in gonad DTC migration may be in association with integrin related proteins ina-1 and mig-15. (1607 aa) | ||||
skr-3 | SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family. (167 aa) | ||||
skr-2 | SKp1 Related (Ubiquitin ligase complex component). (174 aa) | ||||
skr-1 | Skp1-related protein; Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. Involved in synapse elimination in early synapse development. May negatively regulate the apoptotic activity of cep-1 in response to genotoxic stress. Plays a role in sex determination. (176 aa) | ||||
skr-5 | SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family. (145 aa) | ||||
F52C6.2 | Ubiquitin-like domain-containing protein. (228 aa) | ||||
F52C6.3 | Ubiquitin-like domain-containing protein. (197 aa) | ||||
emb-30 | Abnormal embryogenesis protein 30; Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (By similarity). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (By similarity). Developmental role in early embryogenesis and the metaphase to anaphase transition in oocyte and spermatocyte meiosis and mitosis in somatic and germ cells. Required for embryonic anterior- posterior axis formation. Negatively regulat [...] (1027 aa) | ||||
skr-15 | SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family. (184 aa) | ||||
skr-18 | Skp1 domain-containing protein; Belongs to the SKP1 family. (183 aa) | ||||
cya-2 | CYCLIN domain-containing protein; Belongs to the cyclin family. (123 aa) | ||||
ubl-1 | Ubiquitin-like protein 1-40S ribosomal protein S27a; In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family. (163 aa) | ||||
apc-2 | Anaphase-promoting complex subunit 2; Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins. Developmental role in early embryogenesis and the metaphase to anaphase transition in meiosis and mitosis. (731 aa) | ||||
K08C9.7 | Uncharacterized protein. (154 aa) | ||||
cul-6 | Cullin-6; Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. (729 aa) | ||||
skr-21 | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (176 aa) | ||||
gfi-3 | Protein gfi-3; Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins. Required for the metaphase to anaphase transition in meiosis. (800 aa) | ||||
skr-19 | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (155 aa) | ||||
skr-20 | SKp1 Related (Ubiquitin ligase complex component). (173 aa) | ||||
W05G11.2 | Cyclin N-terminal domain-containing protein. (192 aa) | ||||
mat-2 | Anaphase-promoting complex subunit 1; Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins. Developmental role in early embryogenesis and the metaphase to anaphase transition in oocyte and spermatocyte meiosis and mitosis in germ cells. Required for embryonic anterior-posterior axis formation. Plays a role in regulating the abundance of glr-1 receptors [...] (1505 aa) | ||||
skr-10 | SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family. (192 aa) | ||||
mat-1 | Cell division cycle protein 27 homolog; Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (By similarity). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (By similarity). Developmental role in early embryogenesis and the metaphase to anaphase transition in oocyte and spermatocyte meiosis and mitosis in germ cells. Required for embryonic anterior-posterior axis formation. Plays a role in regulating [...] (788 aa) | ||||
skr-6 | SKp1 Related (Ubiquitin ligase complex component). (106 aa) | ||||
Y41D4B.4 | Uncharacterized protein. (656 aa) | ||||
skr-7 | SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family. (194 aa) | ||||
skr-14 | SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family. (168 aa) | ||||
Y48G1C.12 | DOC domain-containing protein. (216 aa) | ||||
bub-3 | Mitotic checkpoint protein bub-3; Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments of chromosomes. Necessary for expression and kinetochore localization of bub-1. Plays a role in synapsis checkpoint signaling inducing apoptosis in response to unsynapsed chromosomes and thus controlling chromosomal segregation during oocyte meiosis. (343 aa) | ||||
skr-4 | SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family. (159 aa) | ||||
cya-1 | G2/mitotic-specific cyclin-A1; Involved in the control of the cell cycle after S phase. May bind to and activate cdk-1 and/or cdk-2 to promote cell cycle progression. Necessary for embryogenesis. Belongs to the cyclin family. Cyclin AB subfamily. (485 aa) | ||||
ZK678.3 | annotation not available (163 aa) |