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| | Y59E9AL.4 | Uncharacterized protein. (555 aa) |
| | B0035.3 | Macro domain-containing protein. (203 aa) |
| | ptps-1 | Putative 6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin (By similarity); Belongs to the PTPS family. (140 aa) |
| | B0205.6 | Aminotran_5 domain-containing protein. (412 aa) |
| | B0244.10 | Putative G-protein coupled receptor B0244.10. (368 aa) |
| | B0244.15 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (384 aa) |
| | B0244.16 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (360 aa) |
| | B0244.17 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (352 aa) |
| | B0244.4 | Putative G-protein coupled receptor B0244.4. (358 aa) |
| | B0244.5 | Putative G-protein coupled receptor B0244.5. (362 aa) |
| | B0244.6 | Putative G-protein coupled receptor-like protein B0244.6. (374 aa) |
| | B0244.7 | Putative G-protein coupled receptor B0244.7. (364 aa) |
| | srtx-1 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (355 aa) |
| | C01G5.5 | Aldo_ket_red domain-containing protein. (287 aa) |
| | mtrr-1 | Methionine synthase reductase; Involved in the reductive regeneration of cob(I)alamin cofactor required for the maintenance of methionine synthase in a functional state. (682 aa) |
| | gsto-2 | Probable glutathione transferase omega-2; Exhibits glutathione-dependent thiol transferase activity. Has dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) (By similarity); Belongs to the GST superfamily. Omega family. (254 aa) |
| | C02D5.4 | Uncharacterized protein; Belongs to the GST superfamily. (254 aa) |
| | vit-5 | Vitellogenin-5; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development. (1603 aa) |
| | mel-32 | Serine hydroxymethyltransferase; Interconversion of serine and glycine; Belongs to the SHMT family. (507 aa) |
| | mthf-1 | Probable methylenetetrahydrofolate reductase. (663 aa) |
| | folt-1 | Folate transporter 1; Folate transporter; Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family. (453 aa) |
| | pnk-1 | PaNtothenate Kinase. (449 aa) |
| | coq-1 | COenzyme Q (Ubiquinone) biosynthesis; Belongs to the FPP/GGPP synthase family. (393 aa) |
| | qns-1 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (703 aa) |
| | C25G4.2 | Esterase C25G4.2; Belongs to the LovG family. (221 aa) |
| | mmab-1 | Corrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (214 aa) |
| | gsto-1 | Glutathione transferase omega-1; Exhibits glutathione-dependent thiol transferase activity (By similarity). Has dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid (By similarity). Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) (By similarity). Protects against environmental stress and oxidative stress ; Belongs to the GST superfamily. Omega family. (250 aa) |
| | C35D10.6 | Aldo_ket_red domain-containing protein. (287 aa) |
| | dhfr-1 | Putative dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). (189 aa) |
| | C37E2.10 | Uncharacterized protein. (223 aa) |
| | C37E2.2 | Uncharacterized protein. (225 aa) |
| | C37E2.3 | Uncharacterized protein. (216 aa) |
| | pks-1 | PolyKetide Synthase. (7752 aa) |
| | hpo-12 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa) |
| | vit-2 | Vitellogenin-2; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development. (1613 aa) |
| | pnk-4 | Pantothenate kinase; Belongs to the type II pantothenate kinase family. (755 aa) |
| | folt-3 | Folate-like transporter 3. (424 aa) |
| | C51E3.6 | Uncharacterized protein. (555 aa) |
| | pmp-3 | Peroxisomal Membrane Protein related. (688 aa) |
| | pyc-1 | Pyruvate carboxylase 1; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1175 aa) |
| | F02A9.10 | Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family. (608 aa) |
| | F02E9.7 | Metallophos domain-containing protein. (419 aa) |
| | F09C8.1 | Lipase_GDSL domain-containing protein. (374 aa) |
| | gst-44 | Glutathione S-Transferase; Belongs to the GST superfamily. (254 aa) |
| | bpl-1 | BPL/LPL catalytic domain-containing protein. (1215 aa) |
| | F13H8.11 | Lipase_GDSL domain-containing protein. (460 aa) |
| | F25B5.6 | Putative folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (521 aa) |
| | F25H9.6 | Flavoprotein domain-containing protein. (237 aa) |
| | nmat-2 | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate. Belongs to the eukaryotic NMN adenylyltransferase family. (223 aa) |
| | pcca-1 | Propionyl-CoA carboxylase alpha chain, mitochondrial; This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites. Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl- CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (By similarity). Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl car [...] (724 aa) |
| | mccc-1 | MethylCrotonoyl-Coenzyme A Carboxylase (Alpha). (671 aa) |
| | cat-4 | GTP cyclohydrolase 1; Involved in serotonin and dopamine biosynthesis that affects movement, mating behavior, foraging behavior, and cell migration. (223 aa) |
| | fasn-1 | Carrier domain-containing protein. (2613 aa) |
| | F32H2.6 | Ketoacyl_synth_N domain-containing protein. (187 aa) |
| | F36A2.9 | Lipase_GDSL domain-containing protein. (565 aa) |
| | alh-3 | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (908 aa) |
| | folt-2 | Folate-like transporter 2; Unlike folt-1, does not appear to act as a folate transporter; Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family. (424 aa) |
| | F37C4.6 | Amino_oxidase domain-containing protein. (544 aa) |
| | F40F9.5 | SoLute Carrier family Related. (585 aa) |
| | agr-1 | AGRin (Synaptic protein) homolog family member. (1473 aa) |
| | moc-3 | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (402 aa) |
| | slc-25A42 | SLC (SoLute Carrier) homolog; Belongs to the mitochondrial carrier (TC 2.A.29) family. (294 aa) |
| | F49E2.1 | Cyclic pyranopterin monophosphate synthase; Isoform mocs1a and isoform mocs1b probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). mocs1a catalyzes the cyclization of GTP to (8S)- 3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and mocs1b catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'- triphosphate to cPMP; In the N-terminal section; belongs to the radical SAM superfamily. MoaA family. (600 aa) |
| | F49H6.5 | Elp3 domain-containing protein. (389 aa) |
| | pccb-1 | Propionyl Coenzyme A Carboxylase Beta subunit. (536 aa) |
| | F53F1.2 | Aldo_ket_red domain-containing protein. (297 aa) |
| | F53F1.3 | Aldo_ket_red domain-containing protein. (283 aa) |
| | F57B9.1 | Putative pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (226 aa) |
| | coq-2 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. (370 aa) |
| | sdn-1 | Probable syndecan; Cell surface proteoglycan that bears heparan sulfate (By similarity). Required for correct mitotic spindle orientation of the ABar blastomere division plane and this may be through modulation of astral microtubule array, and in association with the wnt-signaling proteins mig-5 and dsh-2. Involved in the migration of AQR and PQR neurons, which descend from the Q neuroblasts. Promotes the axon guidance of D-type motor neurons. (288 aa) |
| | pdxk-1 | Putative pyridoxal kinase; Required for synthesis of pyridoxal-5-phosphate from vitamin B6. (331 aa) |
| | gpn-1 | GlyPicaN; Belongs to the glypican family. (543 aa) |
| | vit-3 | Vitellogenin-3; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development. (1603 aa) |
| | vit-4 | Vitellogenin-4; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development. (1603 aa) |
| | slc-25A32 | SLC (SoLute Carrier) homolog; Belongs to the mitochondrial carrier (TC 2.A.29) family. (296 aa) |
| | coq-6 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6; Belongs to the UbiH/COQ6 family. (451 aa) |
| | K07C5.2 | Aldo_ket_red domain-containing protein. (301 aa) |
| | dao-3 | Dauer or Aging adult Overexpression. (303 aa) |
| | K07E3.4 | Uncharacterized protein. (640 aa) |
| | vit-6 | Vitellogenin-6; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development (Probable). May play a role in cholesterol uptake. May be involved in thermotolerance. (1651 aa) |
| | vit-1 | Vitellogenin-1; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development. (1616 aa) |
| | gsto-3 | GST N-terminal domain-containing protein; Belongs to the GST superfamily. (309 aa) |
| | mocs-1 | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (709 aa) |
| | metr-1 | Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). (1249 aa) |
| | R07B7.8 | Lipase_GDSL domain-containing protein. (436 aa) |
| | R07B7.9 | Lipase_GDSL domain-containing protein. (484 aa) |
| | R107.2 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (307 aa) |
| | R10H10.6 | Flavokinase domain-containing protein. (135 aa) |
| | R11E3.2 | Uncharacterized protein. (546 aa) |
| | lin-46 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (391 aa) |
| | flad-1 | Molybdenum cofactor biosynthesis protein-like region; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme; In the N-terminal section; belongs to the MoaB/Mog family. (519 aa) |
| | mmaa-1 | Methylmalonic aciduria type A homolog, mitochondrial; May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone (By similarity). Likely to have a role in propionyl-CoA metabolism and adenosylcobalamin synthesis. (399 aa) |
| | T04G9.4 | ACPS domain-containing protein. (297 aa) |
| | T05G5.5 | Uncharacterized protein T05G5.5; Belongs to the CoaE family. (246 aa) |
| | moc-1 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (435 aa) |
| | anmt-3 | Amine N-MethylTransferase. (283 aa) |
| | T07G12.2 | Uncharacterized protein. (544 aa) |
| | T07G12.4 | Uncharacterized protein. (550 aa) |
| | T07G12.5 | Uncharacterized protein. (555 aa) |
| | pmp-5 | ABC transmembrane type-1 domain-containing protein. (598 aa) |
| | T19D7.7 | Lipase_GDSL domain-containing protein. (471 aa) |
| | nmrk-1 | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. (340 aa) |
| | T28F3.5 | Uncharacterized protein. (1612 aa) |
| | T28H10.1 | ACPS domain-containing protein. (285 aa) |
| | moc-2 | MoCF_biosynth domain-containing protein. (168 aa) |
| | W01A11.7 | Uncharacterized protein. (186 aa) |
| | W02B12.1 | Lipase_GDSL domain-containing protein. (382 aa) |
| | nmat-1 | Nicotinamide-nucleotide adenylyltransferase. (220 aa) |
| | pod-2 | Uncharacterized protein. (2165 aa) |
| | Y106G6E.4 | Probable 5-formyltetrahydrofolate cyclo-ligase; Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5- formyltetrahydrofolate (5-CHO-H(4)PteGlu) to yield 5,10- methenyltetrahydrofolate (By similarity). (206 aa) |
| | Y17G7B.10 | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. (492 aa) |
| | Y18D10A.3 | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. (348 aa) |
| | gfrp-1 | GTP cyclohydrolase I Feedback Regulatory Protein homolog. (95 aa) |
| | coa-1 | Cytochrome Oxidase Assembly subunits. (138 aa) |
| | Y40B10A.9 | Uncharacterized protein. (433 aa) |
| | rft-2 | Riboflavin transporter rft-2; Riboflavin transporter. (476 aa) |
| | rft-1 | Riboflavin transporter rft-1; Riboflavin transporter. Riboflavin transport is Na(+)- independent but pH-sensitive; Belongs to the riboflavin transporter family. (427 aa) |
| | Y4C6B.5 | SLC (SoLute Carrier) homolog. (469 aa) |
| | nprt-1 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. (562 aa) |
| | Y55F3AM.9 | MINDY_DUB domain-containing protein. (379 aa) |
| | coq-3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (268 aa) |
| | Y65B4A.8 | CTP_transf_like domain-containing protein. (461 aa) |
| | Y65B4BR.1 | Lipase_GDSL domain-containing protein. (377 aa) |
| | Y71H2AM.6 | Uncharacterized protein. (277 aa) |
| | Y72A10A.1 | Uncharacterized protein. (242 aa) |
| | Y76A2B.5 | Uncharacterized protein. (283 aa) |
| | Y77E11A.2 | Uncharacterized protein. (370 aa) |
| | unc-52 | Basement membrane proteoglycan; Component of an integrin containing attachment complex, which is required for muscle development and maintenance. Probable structural role in myofilament assembly and/or attachment of the myofilament lattice to the cell membrane. May be an extracellular anchor for integrin receptors in body wall muscles and myoepithelial sheath cells. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably downstream of the integrin complex formed by pat-2 and pat-3. Involved in ovulation. (3375 aa) |
| | ZC116.3 | Cubilin homolog; Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. (4047 aa) |
| | clk-1 | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner; Belongs to the COQ7 family. (187 aa) |
| | ZC443.1 | Aldo_ket_red domain-containing protein. (320 aa) |
| | mmcm-1 | Probable methylmalonyl-CoA mutase, mitochondrial; Involved, in man, in the degradation of several amino acids, odd-chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species (By similarity). (744 aa) |
| | ZK1290.5 | Uncharacterized oxidoreductase ZK1290.5; Belongs to the aldo/keto reductase family. (321 aa) |
| | ZK418.6 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (394 aa) |
| | ZK418.7 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (399 aa) |
| | cblc-1 | MMACHC-like protein; Catalyzes the reductive dealkylation of cyanocobalamin to cob(II)alamin, using FAD or FMN as cofactor and NADPH as cosubstrate. Can also catalyze the glutathione-dependent reductive demethylation of methylcobalamin, and, with much lower efficiency, the glutathione- dependent reductive demethylation of adenosylcobalamin. Under anaerobic conditions cob(I)alamin is the first product; it is highly reactive and is converted to aquocob(II)alamin in the presence of oxygen. Binds cyanocobalamin, adenosylcobalamin, methylcobalamin and other, related vitamin B12 derivatives; [...] (272 aa) |
| | tpk-1 | Thiamin pyrophosphokinase 1; Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Functions cell non-autonomously. (243 aa) |
| | coq-5 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (285 aa) |
| | cTel55X.1 | Uncharacterized protein. (233 aa) |
