Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C10A4.1 | smo-1 | C10A4.1.1 | K12C11.2.1 | Dimer_Tnp_hAT domain-containing protein. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.445 |
| C10A4.1 | ubc-9 | C10A4.1.1 | F29B9.6.2 | Dimer_Tnp_hAT domain-containing protein. | SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like protein smo-1 from the aos-1-uba-2 E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase such as gei-17. Required to sumoylate the ETS transcription factor lin-1 and the Polycomb protein sop-2. Required for embryonic development, fertility, vulval morphogenesis and inhibition of vulval cell fates. Belongs to the ubiquitin-conjugating enzyme family. | 0.490 |
| C23H4.6 | H21P03.2 | C23H4.6a.1 | H21P03.2.1 | AAA_23 domain-containing protein. | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | 0.961 |
| C23H4.6 | R05D3.12 | C23H4.6a.1 | R05D3.12a.1 | AAA_23 domain-containing protein. | Putative DNA topoisomerase 2, mitochondrial; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks (By similarity); Belongs to the type II topoisomerase family. | 0.586 |
| C23H4.6 | T04A8.8 | C23H4.6a.1 | T04A8.8.1 | AAA_23 domain-containing protein. | Rad60-SLD domain-containing protein. | 0.427 |
| C23H4.6 | T27A3.7 | C23H4.6a.1 | T27A3.7.1 | AAA_23 domain-containing protein. | Phorbol-ester/DAG-type domain-containing protein. | 0.961 |
| C23H4.6 | ZK1248.11 | C23H4.6a.1 | ZK1248.11.1 | AAA_23 domain-containing protein. | SP-RING-type domain-containing protein. | 0.961 |
| C23H4.6 | cin-4 | C23H4.6a.1 | ZK1127.7.1 | AAA_23 domain-containing protein. | DNA topoisomerase-like protein cin-4; Plays a role in the removal of cohesin from kinetochores on mitotic chromosomes and is required for centromere resolution. Belongs to the type II topoisomerase family. | 0.585 |
| C23H4.6 | him-6 | C23H4.6a.1 | T04A11.6.1 | AAA_23 domain-containing protein. | Bloom syndrome protein homolog; Participates in DNA replication and repair (By similarity). Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction (By similarity). Negatively regulates sister chromatid exchange (SCE) ; Belongs to the helicase family. RecQ subfamily. | 0.601 |
| C23H4.6 | smc-5 | C23H4.6a.1 | C27A2.1.1 | AAA_23 domain-containing protein. | Structural maintenance of chromosomes protein 5; Core component of the smc-5/smc-6 complex. Functions in DNA double strand break repair by promoting sister- chromatid homologous recombination during meiosis. Acts in a DNA repair pathway for removal of ionizing radiation- and ultraviolet (UV) radiation-induced DNA lesions that is distinct from classical nucleotide excision repair and the translesion synthesis pathway. Also involved in the recovery of stalled replication forks. Belongs to the SMC family. SMC5 subfamily. | 0.967 |
| C23H4.6 | smc-6 | C23H4.6a.1 | F54D5.14.1 | AAA_23 domain-containing protein. | Structural maintenance of chromosomes protein 6 homolog smc-6; Core component of the smc-5/smc-6 complex. Involved in DNA double-strand break repair by promoting sister- chromatid homologous recombination during meiosis. Also plays a role in the DNA damage repair of ultraviolet (UV) radiation-induced DNA lesions. Promotes efficient DNA replication. | 0.551 |
| C23H4.6 | smo-1 | C23H4.6a.1 | K12C11.2.1 | AAA_23 domain-containing protein. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.422 |
| C23H4.6 | top-1 | C23H4.6a.1 | M01E5.5a.2 | AAA_23 domain-containing protein. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)- enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus remo [...] | 0.428 |
| C23H4.6 | top-2 | C23H4.6a.1 | K12D12.1.1 | AAA_23 domain-containing protein. | DNA topoisomerase 2 top-2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks (By similarity). Essential during mitosis in the adult germline and during embryogenesis for proper segregation of daughter chromosomes. Required for centromere resolution during mitosis. Required for chromosome segregation in anaphase of meiosis I during spermatogenesis. Promotes cleavage furrow stability during cytokinesis upon the presence of chromatin obstructions. Promotes DNA break formation upon zygotic genome [...] | 0.607 |
| C23H4.6 | wrn-1 | C23H4.6a.1 | F18C5.2.1 | AAA_23 domain-containing protein. | Probable Werner syndrome ATP-dependent helicase homolog 1; Essential for the formation of DNA replication focal centers; stably associates with foci elements generating binding sites for RP-A. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity. May be involved in the control of genomic stability (By similarity). | 0.601 |
| C53D6.6 | smo-1 | C53D6.6.2 | K12C11.2.1 | Dimer_Tnp_hAT domain-containing protein. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.445 |
| C53D6.6 | ubc-9 | C53D6.6.2 | F29B9.6.2 | Dimer_Tnp_hAT domain-containing protein. | SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like protein smo-1 from the aos-1-uba-2 E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase such as gei-17. Required to sumoylate the ETS transcription factor lin-1 and the Polycomb protein sop-2. Required for embryonic development, fertility, vulval morphogenesis and inhibition of vulval cell fates. Belongs to the ubiquitin-conjugating enzyme family. | 0.490 |
| D2063.1 | sodh-1 | D2063.1.1 | K12G11.3.1 | PKS_ER domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family. | Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.901 |
| D2063.1 | sodh-2 | D2063.1.1 | K12G11.4.1 | PKS_ER domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family. | Alcohol dehydrogenase 2; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.902 |
| F20D1.3 | T04A8.8 | F20D1.3.1 | T04A8.8.1 | Uncharacterized protein. | Rad60-SLD domain-containing protein. | 0.803 |
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