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npp-22 | Nucleoporin ndc-1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope; Belongs to the NDC1 family. (588 aa) | ||||
npp-14 | Nuclear pore complex protein 14; May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex (By similarity). Plays a role in apoptosis by tethering caspase ced-3 to the nuclear membrane preventing its autoprocessing in absence of ced-4. (1390 aa) | ||||
npp-23 | Nuclear Pore complex Protein. (371 aa) | ||||
hsp-70 | Heat Shock Protein; Belongs to the heat shock protein 70 family. (643 aa) | ||||
hsp-3 | Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. (661 aa) | ||||
npp-15 | Nuclear pore complex protein 15; Important for early nematode development. Belongs to the nucleoporin Nup133 family. (1129 aa) | ||||
hsp-110 | Heat shock protein 110. (776 aa) | ||||
gska-3 | Protein kinase domain-containing protein. (381 aa) | ||||
hsp-6 | Heat shock 70 kDa protein F, mitochondrial; Belongs to the heat shock protein 70 family. (657 aa) | ||||
C44H4.6 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (367 aa) | ||||
npp-5 | Nuclear pore complex protein 5; Involved in kinetochore assembly and chromosome segregation during embryonic mitosis. Required for the localization of the NDC80 complex member him-10, the chromosomal passenger complex component air- 2 and nuclear pore complex proteins npp-23 and npp-15 to kinetochores during metaphase. Required for npp-23 localization to the nuclear envelope during interphase. Recruits mdf-1, a component of the spindle assembly checkpoint, to the nuclear envelope. Appears dispensable for the assembly of the nuclear pore complex and for nuclear protein import. (813 aa) | ||||
rae-1 | mRNA export factor rae-1; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors (By similarity). It is specifically important for nuclear mRNA export. Has a role in neuronal development, where it acts downstream of rpm-1 to control axon termination and synapse formation in anterior lateral microtubule (ALM) and posterior lateral microtubule (PLM) mechanosensory neurons. Belo [...] (373 aa) | ||||
F11F1.1 | DUF148 domain-containing protein; Belongs to the heat shock protein 70 family. (607 aa) | ||||
rpa-1 | Probable replication factor A 73 kDa subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (655 aa) | ||||
F21F3.2 | Protein kinase domain-containing protein. (440 aa) | ||||
hsp-1 | Heat shock 70 kDa protein A. (640 aa) | ||||
dnj-11 | DNaJ domain (Prokaryotic heat shock protein). (589 aa) | ||||
F42A6.6 | DUF775 domain-containing protein. (219 aa) | ||||
hsp-4 | Endoplasmic reticulum chaperone BiP homolog; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Required for ER dynamics during the first embryonic cell divisions. Specifically, controls ER transition into sheet-like structures at the onset of mitosis, possibly by regulating homotypic membrane fusion. Belongs to the heat shock protein 70 family. (657 aa) | ||||
F44E5.4 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (645 aa) | ||||
F44E5.5 | annotation not available (645 aa) | ||||
vet-6 | Very Early Transcript. (843 aa) | ||||
stc-1 | STCH (Truncated HSP) family. (450 aa) | ||||
npp-6 | Nuclear Pore complex Protein. (1562 aa) | ||||
bag-1 | BAG family molecular chaperone regulator 1; May inhibit the chaperone activity of HSP70/HSC70 by promoting substrate release in an ATP-dependent manner. (210 aa) | ||||
unc-23 | BAG domain-containing protein. (458 aa) | ||||
sdz-24 | OB domain-containing protein. (236 aa) | ||||
K07F5.12 | Uncharacterized protein. (351 aa) | ||||
npp-1 | Nup54 domain-containing protein. (639 aa) | ||||
npp-3 | Nuclear Pore complex Protein. (1696 aa) | ||||
R03D7.5 | Putative serine/threonine-protein kinase R03D7.5; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (363 aa) | ||||
R03H10.6 | REPA_OB_2 domain-containing protein. (324 aa) | ||||
R03H10.7 | REPA_OB_2 domain-containing protein. (359 aa) | ||||
npp-19 | Nucleoporin NUP35; Functions as a component of the nuclear pore complex (NPC) (By similarity). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors (By similarity). Required for the proper organization of chromosomes on the mitotic spindle during anaphase. (381 aa) | ||||
sir-2.1 | NAD-dependent protein deacetylase sir-2.1; NAD-dependent deacetylase (By similarity). Required for a reduction of the 'Lys-16' acetylation of histone H4 (H4K16ac) on dosage-compensated X chromosomes in hermaphrodites. Plays a role in germ cell and somatic cell apoptosis in response to DNA damage. Functions upstream of daf-16 in the insulin-like signaling pathway, promoting daf-16 mediated transcriptional activation and increased lifespan. May also regulate lifespan independently of daf-16 by modulating the transcription of genes involved in the stress response of the endoplasmic reticu [...] (607 aa) | ||||
npp-2 | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (598 aa) | ||||
T04D3.1 | Uncharacterized protein. (454 aa) | ||||
hip-1 | TPR_REGION domain-containing protein. (422 aa) | ||||
npp-7 | Nuclear Pore complex Protein. (1217 aa) | ||||
npp-12 | Nuclear Pore complex Protein. (1847 aa) | ||||
W02B12.13 | Uncharacterized protein. (262 aa) | ||||
dnj-24 | J domain-containing protein. (249 aa) | ||||
Y106G6D.4 | Protein kinase domain-containing protein. (436 aa) | ||||
Y106G6E.1 | Protein kinase domain-containing protein. (381 aa) | ||||
gsk-3 | Glycogen synthase kinase-3; Phosphorylates oma-1, a regulator of the oocyte-to-embryo transition, enabling its degradation. Phosphorylates skn-1, preventing it from accumulating in nuclei and thus inhibiting phase II gene expression in the oxidative stress defense. Involved in mesendoderm specification and mitotic spindle orientation in EMS blastomeres. Thought to be a branch point in these processes as proteins downstream are not required. Negatively regulates Wnt signaling in vulval precursor cells and acts as a Wnt-independent repressor of med-1 and med-2 in the C lineage inhibiting [...] (362 aa) | ||||
npp-13 | Nuclear pore protein. (787 aa) | ||||
npp-8 | Nuclear Pore complex Protein. (1340 aa) | ||||
npp-18 | Nucleoporin SEH1; Probable component of the nuclear pore complex (NPC) which is involved in the trafficking of macromolecules between the cytoplasm and nucleus. (363 aa) | ||||
hsf-1 | HSF_DOMAIN domain-containing protein. (671 aa) | ||||
npp-4 | Nuclear Pore complex Protein. (538 aa) | ||||
npp-16 | Nuclear Pore complex Protein. (497 aa) | ||||
npp-20 | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat (By similarity). Required for the nuclear import of hcp-4 during mitotic prophase, this step is essential for centrosome assembly and resolution. Belongs to the WD repeat SEC13 family. (313 aa) | ||||
gcy-15 | Receptor-type guanylate cyclase gcy-15; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). (1115 aa) | ||||
ZK1053.4 | Uncharacterized protein. (701 aa) | ||||
npp-24 | Protein npp-24. (655 aa) | ||||
npp-10 | Nuclear pore complex protein Nup98-Nup96; Nup98 and Nup96 play a role in the bidirectional transport across the nucleoporin complex (NPC). Required for the nuclear import of hcp-4 during mitotic prophase, this step is essential for centrosome assembly and resolution. Regulates nucleoporin npp-5 localization to the nuclear membrane during interphase and to kinetochores during metaphase. Has a role in P granule integrity; may promote the 'liquid phase' of P granules by increasing the number of interacting RNA-protein complexes. Binds nos-2 mRNA, probably indirectly, and promotes its accu [...] (1678 aa) |