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his-46 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) | ||||
npp-22 | Nucleoporin ndc-1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope; Belongs to the NDC1 family. (588 aa) | ||||
B0545.4 | Dimer_Tnp_hAT domain-containing protein. (117 aa) | ||||
npp-14 | Nuclear pore complex protein 14; May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex (By similarity). Plays a role in apoptosis by tethering caspase ced-3 to the nuclear membrane preventing its autoprocessing in absence of ced-4. (1390 aa) | ||||
npp-23 | Nuclear Pore complex Protein. (371 aa) | ||||
C10A4.1 | Dimer_Tnp_hAT domain-containing protein. (626 aa) | ||||
npp-15 | Nuclear pore complex protein 15; Important for early nematode development. Belongs to the nucleoporin Nup133 family. (1129 aa) | ||||
his-37 | Histone H4. (103 aa) | ||||
C53D6.6 | Dimer_Tnp_hAT domain-containing protein. (615 aa) | ||||
npp-5 | Nuclear pore complex protein 5; Involved in kinetochore assembly and chromosome segregation during embryonic mitosis. Required for the localization of the NDC80 complex member him-10, the chromosomal passenger complex component air- 2 and nuclear pore complex proteins npp-23 and npp-15 to kinetochores during metaphase. Required for npp-23 localization to the nuclear envelope during interphase. Recruits mdf-1, a component of the spindle assembly checkpoint, to the nuclear envelope. Appears dispensable for the assembly of the nuclear pore complex and for nuclear protein import. (813 aa) | ||||
his-50 | Histone H4. (103 aa) | ||||
rae-1 | mRNA export factor rae-1; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors (By similarity). It is specifically important for nuclear mRNA export. Has a role in neuronal development, where it acts downstream of rpm-1 to control axon termination and synapse formation in anterior lateral microtubule (ALM) and posterior lateral microtubule (PLM) mechanosensory neurons. Belo [...] (373 aa) | ||||
his-31 | Histone H4. (103 aa) | ||||
his-64 | Histone H4. (103 aa) | ||||
ubc-9 | SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like protein smo-1 from the aos-1-uba-2 E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase such as gei-17. Required to sumoylate the ETS transcription factor lin-1 and the Polycomb protein sop-2. Required for embryonic development, fertility, vulval morphogenesis and inhibition of vulval cell fates. Belongs to the ubiquitin-conjugating enzyme family. (166 aa) | ||||
F29B9.8 | Uncharacterized protein. (381 aa) | ||||
spd-2 | Spindle-defective protein 2; Required both for centrosome duplication and maturation. Required for pericentriolar material (PCM) recruitment. (824 aa) | ||||
sdz-19 | SKN-1 Dependent Zygotic transcript. (139 aa) | ||||
his-5 | Histone H4. (103 aa) | ||||
F46F2.4 | annotation not available (364 aa) | ||||
his-56 | Histone H4. (103 aa) | ||||
his-60 | Histone H4. (103 aa) | ||||
npp-6 | Nuclear Pore complex Protein. (1562 aa) | ||||
uev-2 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (230 aa) | ||||
H42K12.3 | Uncharacterized protein. (522 aa) | ||||
his-38 | Histone H4. (103 aa) | ||||
his-18 | Histone H4. (103 aa) | ||||
his-28 | Histone H4. (103 aa) | ||||
K07F5.12 | Uncharacterized protein. (351 aa) | ||||
npp-1 | Nup54 domain-containing protein. (639 aa) | ||||
K09A11.1 | BED-type domain-containing protein. (605 aa) | ||||
smo-1 | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] (91 aa) | ||||
npp-3 | Nuclear Pore complex Protein. (1696 aa) | ||||
npp-19 | Nucleoporin NUP35; Functions as a component of the nuclear pore complex (NPC) (By similarity). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors (By similarity). Required for the proper organization of chromosomes on the mitotic spindle during anaphase. (381 aa) | ||||
npp-2 | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (598 aa) | ||||
T04A8.8 | Rad60-SLD domain-containing protein. (328 aa) | ||||
his-1 | Histone H4. (103 aa) | ||||
npp-7 | Nuclear Pore complex Protein. (1217 aa) | ||||
his-67 | Histone H4. (103 aa) | ||||
npp-12 | Nuclear Pore complex Protein. (1847 aa) | ||||
npp-13 | Nuclear pore protein. (787 aa) | ||||
npp-8 | Nuclear Pore complex Protein. (1340 aa) | ||||
npp-18 | Nucleoporin SEH1; Probable component of the nuclear pore complex (NPC) which is involved in the trafficking of macromolecules between the cytoplasm and nucleus. (363 aa) | ||||
npp-4 | Nuclear Pore complex Protein. (538 aa) | ||||
npp-16 | Nuclear Pore complex Protein. (497 aa) | ||||
npp-20 | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat (By similarity). Required for the nuclear import of hcp-4 during mitotic prophase, this step is essential for centrosome assembly and resolution. Belongs to the WD repeat SEC13 family. (313 aa) | ||||
dve-1 | Homeobox domain-containing protein. (468 aa) | ||||
his-26 | Histone H4. (103 aa) | ||||
his-10 | Histone H4. (103 aa) | ||||
his-14 | Histone H4. (103 aa) | ||||
npp-24 | Protein npp-24. (655 aa) | ||||
npp-10 | Nuclear pore complex protein Nup98-Nup96; Nup98 and Nup96 play a role in the bidirectional transport across the nucleoporin complex (NPC). Required for the nuclear import of hcp-4 during mitotic prophase, this step is essential for centrosome assembly and resolution. Regulates nucleoporin npp-5 localization to the nuclear membrane during interphase and to kinetochores during metaphase. Has a role in P granule integrity; may promote the 'liquid phase' of P granules by increasing the number of interacting RNA-protein complexes. Binds nos-2 mRNA, probably indirectly, and promotes its accu [...] (1678 aa) | ||||
lin-15B | Protein lin-15B; Synthetic multivulva (synMuv) class B protein. SynMuv proteins are required to repress the induction of vulval development. Acts redundantly with SynMuv class A protein lin-15A to negatively regulate vulval development. Regulates let-23 basal activity. (1440 aa) | ||||
ZK662.5 | Uncharacterized protein. (598 aa) |