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his-48 | Probable histone H2B 4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (123 aa) | ||||
his-46 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) | ||||
npp-14 | Nuclear pore complex protein 14; May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex (By similarity). Plays a role in apoptosis by tethering caspase ced-3 to the nuclear membrane preventing its autoprocessing in absence of ced-4. (1390 aa) | ||||
npp-23 | Nuclear Pore complex Protein. (371 aa) | ||||
rpb-2 | DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...] (1194 aa) | ||||
npp-15 | Nuclear pore complex protein 15; Important for early nematode development. Belongs to the nucleoporin Nup133 family. (1129 aa) | ||||
rpb-3 | RPOLD domain-containing protein. (282 aa) | ||||
his-41 | Probable histone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (123 aa) | ||||
his-37 | Histone H4. (103 aa) | ||||
npp-5 | Nuclear pore complex protein 5; Involved in kinetochore assembly and chromosome segregation during embryonic mitosis. Required for the localization of the NDC80 complex member him-10, the chromosomal passenger complex component air- 2 and nuclear pore complex proteins npp-23 and npp-15 to kinetochores during metaphase. Required for npp-23 localization to the nuclear envelope during interphase. Recruits mdf-1, a component of the spindle assembly checkpoint, to the nuclear envelope. Appears dispensable for the assembly of the nuclear pore complex and for nuclear protein import. (813 aa) | ||||
his-54 | Histone H2B 2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (123 aa) | ||||
his-52 | Histone H2B 2. (123 aa) | ||||
his-50 | Histone H4. (103 aa) | ||||
his-44 | Histone H2B 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (122 aa) | ||||
rae-1 | mRNA export factor rae-1; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors (By similarity). It is specifically important for nuclear mRNA export. Has a role in neuronal development, where it acts downstream of rpm-1 to control axon termination and synapse formation in anterior lateral microtubule (ALM) and posterior lateral microtubule (PLM) mechanosensory neurons. Belo [...] (373 aa) | ||||
his-31 | Histone H4. (103 aa) | ||||
his-34 | Histone H2B 1. (122 aa) | ||||
his-64 | Histone H4. (103 aa) | ||||
rpb-12 | RNA Polymerase II (B) subunit. (62 aa) | ||||
rpb-8 | Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively (By similarity); Belongs to the eukaryotic RPB8 RNA polymerase subunit family. (148 aa) | ||||
his-29 | Histone H2B 1. (122 aa) | ||||
ama-1 | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] (1856 aa) | ||||
rpb-4 | RPOL4c domain-containing protein. (144 aa) | ||||
his-8 | Histone H2B 2. (123 aa) | ||||
his-39 | Histone domain-containing protein; Belongs to the histone H2B family. (67 aa) | ||||
his-5 | Histone H4. (103 aa) | ||||
his-56 | Histone H4. (103 aa) | ||||
his-58 | Probable histone H2B 4. (123 aa) | ||||
his-60 | Histone H4. (103 aa) | ||||
his-62 | Probable histone H2B 4. (123 aa) | ||||
npp-6 | Nuclear Pore complex Protein. (1562 aa) | ||||
his-66 | Probable histone H2B 4. (123 aa) | ||||
rpb-5 | DNA-directed RNA polymerases I, II, and III subunit RPABC1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RPB5 is part of the lower [...] (211 aa) | ||||
ran-1 | GTP-binding nuclear protein ran-1; Ran GTPase system comprises ran-1, ran-2 and ran-3 and is essential in nucleocytoplasmic transport. Ran-1 is a GTP-binding protein that mediates the interaction between mitotic chromosomes and kinetochore microtubules. Plays a crucial role in nuclear envelope assembly at the end of each cell division. Required for the import of protein into the nucleus and also for RNA export. RCC1 (ran-3)/Ran (ran-1) complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. (215 aa) | ||||
his-38 | Histone H4. (103 aa) | ||||
his-18 | Histone H4. (103 aa) | ||||
his-22 | Histone H2B 2. (123 aa) | ||||
his-28 | Histone H4. (103 aa) | ||||
his-20 | Histone H2B 2. (123 aa) | ||||
K07F5.12 | Uncharacterized protein. (351 aa) | ||||
npp-1 | Nup54 domain-containing protein. (639 aa) | ||||
npp-3 | Nuclear Pore complex Protein. (1696 aa) | ||||
npp-19 | Nucleoporin NUP35; Functions as a component of the nuclear pore complex (NPC) (By similarity). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors (By similarity). Required for the proper organization of chromosomes on the mitotic spindle during anaphase. (381 aa) | ||||
htz-1 | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] (140 aa) | ||||
npp-2 | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (598 aa) | ||||
his-4 | Histone H2B 2. (123 aa) | ||||
his-1 | Histone H4. (103 aa) | ||||
npp-7 | Nuclear Pore complex Protein. (1217 aa) | ||||
his-67 | Histone H4. (103 aa) | ||||
npp-12 | Nuclear Pore complex Protein. (1847 aa) | ||||
rpb-11 | Probable DNA-directed RNA polymerase II subunit RPB11; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity). (122 aa) | ||||
npp-13 | Nuclear pore protein. (787 aa) | ||||
rpb-10 | DNA-directed RNA polymerases I, II, and III subunit RPABC5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RBP10 is part of the cor [...] (67 aa) | ||||
npp-8 | Nuclear Pore complex Protein. (1340 aa) | ||||
npp-18 | Nucleoporin SEH1; Probable component of the nuclear pore complex (NPC) which is involved in the trafficking of macromolecules between the cytoplasm and nucleus. (363 aa) | ||||
rpb-7 | S1 motif domain-containing protein. (197 aa) | ||||
npp-4 | Nuclear Pore complex Protein. (538 aa) | ||||
npp-16 | Nuclear Pore complex Protein. (497 aa) | ||||
npp-20 | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat (By similarity). Required for the nuclear import of hcp-4 during mitotic prophase, this step is essential for centrosome assembly and resolution. Belongs to the WD repeat SEC13 family. (313 aa) | ||||
rpb-9 | TFIIS-type domain-containing protein; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (167 aa) | ||||
his-26 | Histone H4. (103 aa) | ||||
his-10 | Histone H4. (103 aa) | ||||
his-11 | Histone H2B 1. (122 aa) | ||||
his-14 | Histone H4. (103 aa) | ||||
his-15 | Histone H2B 1. (122 aa) | ||||
npp-10 | Nuclear pore complex protein Nup98-Nup96; Nup98 and Nup96 play a role in the bidirectional transport across the nucleoporin complex (NPC). Required for the nuclear import of hcp-4 during mitotic prophase, this step is essential for centrosome assembly and resolution. Regulates nucleoporin npp-5 localization to the nuclear membrane during interphase and to kinetochores during metaphase. Has a role in P granule integrity; may promote the 'liquid phase' of P granules by increasing the number of interacting RNA-protein complexes. Binds nos-2 mRNA, probably indirectly, and promotes its accu [...] (1678 aa) |