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| | pph-5 | Serine/threonine-protein phosphatase 5; Serine/threonine-protein phosphatase. Dephosphorylates cdc-37. Probably by dephosphorylating separase sep-1, may be involved in sep-1-mediated exocytosis of cortical granules during meiotic anaphase and mitotic cytokinesis. (496 aa) |
| | C02B10.6 | Tyrosine-protein phosphatase. (398 aa) |
| | lip-1 | Dual specificity protein phosphatase lip-1; Dephosphorylates MAP kinase mpk-1. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) |
| | kxd-1 | KxDL domain-containing protein. (140 aa) |
| | pptr-2 | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (607 aa) |
| | C16A3.2 | Uncharacterized protein. (221 aa) |
| | C17H12.3 | Tyrosine-protein phosphatase. (374 aa) |
| | C24F3.2 | Uncharacterized protein. (272 aa) |
| | C33H5.16 | Tyrosine-protein phosphatase. (341 aa) |
| | C55B7.3 | Tyrosine-protein phosphatase. (346 aa) |
| | brap-2 | BRCA1-associated protein homolog 2; Controls the stress response to increased levels of reactive oxygen species by modulating the brc-1-dependent expression of cki-1. (590 aa) |
| | vhp-1 | Tyrosine-protein phosphatase vhp-1; Acts preferentially on the c-Jun N-terminal kinase (JNK) and p38 MAPKs. Plays an important role in the heavy metal stress response and in axon regeneration by negatively regulating the kgb-1 (JNK-like) and the pmk-1 (p38-type) MAPK signaling pathways. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (661 aa) |
| | F10G8.1 | Tyrosine-protein phosphatase. (346 aa) |
| | F13D11.3 | Uncharacterized protein. (174 aa) |
| | ppfr-1 | Serine/threonine-protein phosphatase 4 regulatory subunit 1; Probable regulatory subunit of serine/threonine-protein phosphatase PP4 which may play a role in meiosis and embryonic mitosis. Probably in association with catalytic subunit pph-4.1, regulates microtubule severing during oocyte meiosis II by dephosphorylating and likely activating mei-1, a component of the katanin microtubule severing complex. (1562 aa) |
| | F20B6.1 | annotation not available (166 aa) |
| | ubq-1 | Ubiquitin-related; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degrad [...] (838 aa) |
| | F34H10.1 | Probable ribosomal protein F34H10.1; Belongs to the eukaryotic ribosomal protein eS31 family. (142 aa) |
| | F36H12.10 | Tyrosine-protein phosphatase. (398 aa) |
| | let-92 | Serine/threonine-protein phosphatase 2A catalytic subunit; Protein phosphatase which plays an essential role in early embryonic cell division. Probably together with constant regulatory subunit paa-1 and regulatory subunit sur-6, positively regulates centriole duplication by preventing the degradation of sas-5 and kinase zyg-1. In addition, plays a role in the recruitment of sas- 6 and maybe sas-5 to centrioles and may dephosphorylate sas-5 and zyg-1 negative regulator szy-20. During vulva development, may play a role with regulatory subunits paa-1 and sur-6 in the induction of vulva c [...] (318 aa) |
| | F40A3.3 | Phosphatidylethanolamine-binding protein homolog F40A3.3. (226 aa) |
| | F46C5.6 | Uncharacterized protein. (945 aa) |
| | F47B3.1 | Tyrosine-protein phosphatase. (363 aa) |
| | F47B3.2 | Uncharacterized protein. (130 aa) |
| | F47B3.6 | Tyrosine-protein phosphatase. (363 aa) |
| | F47B3.7 | Tyrosine-protein phosphatase. (374 aa) |
| | paa-1 | Probable serine/threonine-protein phosphatase PP2A regulatory subunit; Acts as a scaffolding protein for phosphatase let-92 and its regulatory subunits (Probable). Probably together with let-92 and regulatory subunit sur-6, regulates centriole duplication, microtubule outgrowth and mitotic spindle stability during early embryonic cell division by preventing the degradation of sas-5 and kinase zyg-1. During vulva development, may play a role with phosphatase let-92 and regulatory subunit sur-6 in the induction of vulva cell precursors by positively regulating let-60/Ras- MAP kinase sign [...] (590 aa) |
| | F52C6.2 | Ubiquitin-like domain-containing protein. (228 aa) |
| | F52C6.3 | Ubiquitin-like domain-containing protein. (197 aa) |
| | ubl-1 | Ubiquitin-like protein 1-40S ribosomal protein S27a; In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family. (163 aa) |
| | K07F5.8 | Tyrosine-protein phosphatase. (284 aa) |
| | K08C9.7 | Uncharacterized protein. (154 aa) |
| | pptr-1 | Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1; Probable regulatory subunit of serine/threonine-protein phosphatase let-92 which negatively regulates the insulin receptor signaling cascade composed of daf-2, age-1, akt-1, akt-2 and sgk-1 by promoting the dephosphorylation of akt-1 on 'Thr-350'. Negatively regulates several functions controlled by the insulin pathway including dauer formation, lifespan, fat storage and stress resistance. Plays a role in the asymmetric segregation of the P granule components during embryonic cell divisions but does not play an essentia [...] (542 aa) |
| | Y39B6A.13 | Uncharacterized protein. (208 aa) |
| | ral-1 | RAL (Ras-related GTPase) homolog. (254 aa) |
| | Y54F10BM.13 | Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (227 aa) |
| | Y54F10BM.3 | Uncharacterized protein. (781 aa) |
| | paqr-3 | Progestin and AdipoQ Receptor family. (328 aa) |
| | lin-45 | Raf homolog serine/threonine-protein kinase; Protein kinase that participates in the induction of vulva and has roles in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Plays a role in responses to M.nematophilum- mediated bacterial infection by promoting tail swelling and preventing constipation. Positively regulates lifespan upstream of mek-2 and mpk-1. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. (855 aa) |
| | ubq-2 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] (128 aa) |
| | ZK354.8 | Tyrosine-protein phosphatase. (483 aa) |
| | ZK484.7 | Tyrosine-protein phosphatase. (344 aa) |
| | let-60 | Ras protein let-60; The level of let-60 controls the switch between vulval and hypodermal cell fates during C.elegans vulval induction. May stimulate the guanine nucleotide exchange factor (GEF) activity of rap-1. Belongs to the small GTPase superfamily. Ras family. (184 aa) |
