STRINGSTRING
his-51 his-51 his-35 his-35 his-47 his-47 his-53 his-53 his-43 his-43 his-33 his-33 ubq-1 ubq-1 F34H10.1 F34H10.1 his-30 his-30 F37A4.5 F37A4.5 F42A6.5 F42A6.5 his-7 his-7 F52C6.2 F52C6.2 F52C6.3 F52C6.3 str-79 str-79 his-57 his-57 his-61 his-61 his-65 his-65 ubl-1 ubl-1 K02D10.4 K02D10.4 his-19 his-19 his-21 his-21 rpn-11 rpn-11 K08C9.7 K08C9.7 his-3 his-3 his-68 his-68 str-81 str-81 Y76B12C.6 Y76B12C.6 ubq-2 ubq-2 htas-1 htas-1 his-16 his-16 his-12 his-12 brc-1 brc-1 kxd-1 kxd-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
his-51Histone H2A. (127 aa)
his-35Histone H2A; Belongs to the histone H2A family. (127 aa)
his-47Histone H2A; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (127 aa)
his-53Histone H2A. (127 aa)
his-43Histone H2A. (127 aa)
his-33Histone H2A. (127 aa)
ubq-1Ubiquitin-related; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degrad [...] (838 aa)
F34H10.1Probable ribosomal protein F34H10.1; Belongs to the eukaryotic ribosomal protein eS31 family. (142 aa)
his-30Histone H2A. (127 aa)
F37A4.5Uncharacterized protein F37A4.5; Belongs to the peptidase M67A family. (319 aa)
F42A6.5BRCT domain-containing protein. (102 aa)
his-7Histone H2A. (127 aa)
F52C6.2Ubiquitin-like domain-containing protein. (228 aa)
F52C6.3Ubiquitin-like domain-containing protein. (197 aa)
str-79Seven TM Receptor. (314 aa)
his-57Histone H2A; Belongs to the histone H2A family. (147 aa)
his-61Histone H2A. (127 aa)
his-65Histone H2A. (127 aa)
ubl-1Ubiquitin-like protein 1-40S ribosomal protein S27a; In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family. (163 aa)
K02D10.4Uncharacterized protein K02D10.4. (267 aa)
his-19Histone H2A. (127 aa)
his-21Histone H2A. (127 aa)
rpn-1126S proteasome non-ATPase regulatory subunit 14; Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity). (312 aa)
K08C9.7Uncharacterized protein. (154 aa)
his-3Histone H2A. (127 aa)
his-68Histone H2A. (127 aa)
str-81Seven TM Receptor. (365 aa)
Y76B12C.6Uncharacterized protein. (554 aa)
ubq-2Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] (128 aa)
htas-1Histone H2A; Belongs to the histone H2A family. (145 aa)
his-16Histone H2A. (127 aa)
his-12Histone H2A. (127 aa)
brc-1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of polyubiquitin chains and plays a central role in DNA repair. Plays a role in triggering cellular responses at damage sites in response to DNA damage that may be induced by UV and ionizing radiation for example. Functions in double-strand break repair, and is required for homologous recombination between sister chromatids in meiotic and mitotic cells. In particular, protects against chromosome non-disjunction and nuclear fragmentation during meiotic double-strand [...] (612 aa)
kxd-1KxDL domain-containing protein. (140 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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