STRINGSTRING
ubq-2 ubq-2 kxd-1 kxd-1 prmt-5 prmt-5 set-32 set-32 set-6 set-6 set-11 set-11 F34H10.1 F34H10.1 ubl-1 ubl-1 K08C9.7 K08C9.7 set-13 set-13 set-15 set-15 set-1 set-1 set-19 set-19 set-20 set-20 set-33 set-33 set-21 set-21 Y37E3.1 Y37E3.1 atm-1 atm-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ubq-2Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] (128 aa)
kxd-1KxDL domain-containing protein. (140 aa)
prmt-5Protein arginine N-methyltransferase 5; Catalyzes the symmetrical dimethylation of arginine residues in targets such as small nuclear ribonucleoproteins, histone H2A/H4 and cbp-1. Dimethylation occurs in a distributive manner where the protein is released after the addition of the first methyl group prior to rebinding for the addition of the second methyl group. Plays a role in the negative regulation of DNA damage-induced apoptosis. By methylating cbp-1, may prevent apoptosis by repressing the capacity of cbp-1 to enhance cep-1 dependent transcription activation of the programmed cell [...] (734 aa)
set-32SET domain-containing protein. (517 aa)
set-6SET domain-containing protein. (708 aa)
set-11SET (Trithorax/polycomb) domain containing. (367 aa)
F34H10.1Probable ribosomal protein F34H10.1; Belongs to the eukaryotic ribosomal protein eS31 family. (142 aa)
ubl-1Ubiquitin-like protein 1-40S ribosomal protein S27a; In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family. (163 aa)
K08C9.7Uncharacterized protein. (154 aa)
set-13SET domain-containing protein. (402 aa)
set-15SET domain-containing protein. (611 aa)
set-1Histone-lysine N-methyltransferase set-1; Histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched on hermaphrodite X chromosomes and during mitosis. Involved in dosage compensation by repression of X-linked gene expression in hermaphrodites. Plays a role in growth and body fat regulation downstream of the TOR complex 2 pathway. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. PR/SET subfamily. (242 aa)
set-19SET domain-containing protein. (944 aa)
set-20SET (Trithorax/polycomb) domain containing. (552 aa)
set-33SET (Trithorax/polycomb) domain containing. (551 aa)
set-21SET domain-containing protein. (568 aa)
Y37E3.1Uncharacterized protein. (402 aa)
atm-1Serine/threonine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling in the presence of DNA double strand breaks (DSBs) and other forms of DNA damage induced by ionizing radiation and other genotoxic stresses such as UV. Plays a role in maintaining genome stability. Belongs to the PI3/PI4-kinase family. ATM subfamily. (2378 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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