STRINGSTRING
his-64 his-64 his-48 his-48 his-46 his-46 his-41 his-41 his-37 his-37 his-54 his-54 his-52 his-52 his-50 his-50 his-44 his-44 his-31 his-31 his-34 his-34 imb-1 imb-1 his-29 his-29 his-8 his-8 his-39 his-39 his-5 his-5 his-56 his-56 his-58 his-58 his-60 his-60 his-62 his-62 orc-2 orc-2 his-66 his-66 his-38 his-38 his-18 his-18 his-22 his-22 his-28 his-28 his-20 his-20 htz-1 htz-1 his-4 his-4 his-1 his-1 his-67 his-67 Y104H12D.2 Y104H12D.2 Y104H12D.4 Y104H12D.4 orc-1 orc-1 orc-4 orc-4 orc-5 orc-5 his-26 his-26 his-10 his-10 his-11 his-11 his-14 his-14 his-15 his-15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
his-64Histone H4. (103 aa)
his-48Probable histone H2B 4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (123 aa)
his-46Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
his-41Probable histone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (123 aa)
his-37Histone H4. (103 aa)
his-54Histone H2B 2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (123 aa)
his-52Histone H2B 2. (123 aa)
his-50Histone H4. (103 aa)
his-44Histone H2B 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (122 aa)
his-31Histone H4. (103 aa)
his-34Histone H2B 1. (122 aa)
imb-1Importin N-terminal domain-containing protein. (896 aa)
his-29Histone H2B 1. (122 aa)
his-8Histone H2B 2. (123 aa)
his-39Histone domain-containing protein; Belongs to the histone H2B family. (67 aa)
his-5Histone H4. (103 aa)
his-56Histone H4. (103 aa)
his-58Probable histone H2B 4. (123 aa)
his-60Histone H4. (103 aa)
his-62Probable histone H2B 4. (123 aa)
orc-2Origin recognition complex subunit 2; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity). (430 aa)
his-66Probable histone H2B 4. (123 aa)
his-38Histone H4. (103 aa)
his-18Histone H4. (103 aa)
his-22Histone H2B 2. (123 aa)
his-28Histone H4. (103 aa)
his-20Histone H2B 2. (123 aa)
htz-1Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] (140 aa)
his-4Histone H2B 2. (123 aa)
his-1Histone H4. (103 aa)
his-67Histone H4. (103 aa)
Y104H12D.2Uncharacterized protein. (327 aa)
Y104H12D.4Uncharacterized protein. (107 aa)
orc-1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (636 aa)
orc-4ORC (Origin Recognition Complex) subunit. (387 aa)
orc-5ORC (Origin Recognition Complex) subunit. (396 aa)
his-26Histone H4. (103 aa)
his-10Histone H4. (103 aa)
his-11Histone H2B 1. (122 aa)
his-14Histone H4. (103 aa)
his-15Histone H2B 1. (122 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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