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rps-6 rps-6 rps-9 rps-9 rps-8 rps-8 rpl-25.2 rpl-25.2 rps-22 rps-22 rpl-7 rpl-7 rpl-5 rpl-5 rps-12 rps-12 rpl-25.1 rpl-25.1 rps-27 rps-27 rps-1 rps-1 eif-1.A eif-1.A rpl-12 rpl-12 inx-7 inx-7 rps-25 rps-25 cif-1 cif-1 rpl-15 rpl-15 eif-3.D eif-3.D rpl-28 rpl-28 rpl-9 rpl-9 rpl-6 rpl-6 rps-16 rps-16 rps-5 rps-5 rps-19 rps-19 rps-24 rps-24 T07A9.14 T07A9.14 rps-17 rps-17 eif-3.K eif-3.K T16G1.9 T16G1.9 rpl-11.1 rpl-11.1 eif-3.C eif-3.C T23F2.2 T23F2.2 rpl-32 rpl-32 rpl-39 rpl-39 rps-3 rps-3 eif-3.L eif-3.L rps-13 rps-13 rpl-21 rpl-21 kxd-1 kxd-1 rpl-36.A rpl-36.A nbs-1 nbs-1 rpl-19 rpl-19 rpl-38 rpl-38 rpl-14 rpl-14 C03H5.5 C03H5.5 rpl-29 rpl-29 eif-3.E eif-3.E rps-29 rps-29 rps-0 rps-0 rpl-23 rpl-23 rpl-2 rpl-2 rpl-4 rpl-4 W01D2.1 W01D2.1 rpl-7A rpl-7A rpl-30 rpl-30 rps-20 rps-20 rpl-31 rpl-31 ZK686.1 ZK686.1 rpl-35 rpl-35 rps-7 rps-7 Y94H6A.3 Y94H6A.3 eif-3.I eif-3.I Y73B3A.18 Y73B3A.18 rps-11 rps-11 rla-2 rla-2 rps-18 rps-18 eif-3.B eif-3.B rpl-17 rpl-17 Y48G8AL.7 Y48G8AL.7 rpl-43 rpl-43 rpl-18 rpl-18 rps-4 rps-4 rps-28 rps-28 eif-3.J eif-3.J Y37E3.8 Y37E3.8 rla-1 rla-1 rpl-22 rpl-22 egl-45 egl-45 rpl-13 rpl-13 C37A2.7 C37A2.7 eif-3.H eif-3.H rpl-34 rpl-34 rps-2 rps-2 rpl-27 rpl-27 rpl-37 rpl-37 rpl-24.1 rpl-24.1 pqn-24 pqn-24 rps-10 rps-10 D1081.6 D1081.6 eif-3.F eif-3.F rpl-20 rpl-20 rpl-11.2 rpl-11.2 rpl-10 rpl-10 rpl-33 rpl-33 rpl-3 rpl-3 F13D11.4 F13D11.4 F13H10.6 F13H10.6 eif-3.G eif-3.G rla-0 rla-0 rpl-26 rpl-26 rps-23 rps-23 spe-45 spe-45 rps-15 rps-15 rps-21 rps-21 rpl-36 rpl-36 rps-26 rps-26
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rps-640S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (By similarity). Negatively regulates lifespan ; Belongs to the eukaryotic ribosomal protein eS6 family. (246 aa)
rps-940S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (189 aa)
rps-840S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa)
rpl-25.260S ribosomal protein L23a 2; This protein binds to a specific region on the 26S rRNA. (146 aa)
rps-22Ribosomal Protein, Small subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rpl-760S ribosomal protein L7; Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity). (244 aa)
rpl-560S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (293 aa)
rps-1240S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (140 aa)
rpl-25.160S ribosomal protein L23a 1; This protein binds to a specific region on the 26S rRNA. (147 aa)
rps-2740S ribosomal protein S27. (83 aa)
rps-140S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family. (257 aa)
eif-1.AS1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (216 aa)
rpl-1260S ribosomal protein L12; Binds directly to 26S ribosomal RNA; Belongs to the universal ribosomal protein uL11 family. (165 aa)
inx-7Innexin-7; Structural component of the gap junctions. Belongs to the pannexin family. (556 aa)
rps-2540S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (117 aa)
cif-1COP9/Signalosome and eIF3 complex-shared subunit 1; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation (Potential). Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essen [...] (390 aa)
rpl-1560S ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family. (204 aa)
eif-3.DEukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs. (570 aa)
rpl-2860S ribosomal protein L28; Belongs to the eukaryotic ribosomal protein eL28 family. (126 aa)
rpl-960S ribosomal protein L9; Belongs to the universal ribosomal protein uL6 family. (189 aa)
rpl-660S ribosomal protein L6; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL6 family. (217 aa)
rps-1640S ribosomal protein S16. (144 aa)
rps-540S ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (210 aa)
rps-1940S ribosomal protein S19; Belongs to the eukaryotic ribosomal protein eS19 family. (146 aa)
rps-24Ribosomal Protein, Small subunit. (131 aa)
T07A9.14Uncharacterized protein. (204 aa)
rps-1740S ribosomal protein S17; Belongs to the eukaryotic ribosomal protein eS17 family. (130 aa)
eif-3.KEukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (240 aa)
T16G1.9ANK_REP_REGION domain-containing protein. (945 aa)
rpl-11.160S ribosomal protein L11-1; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throu [...] (196 aa)
eif-3.CEukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (898 aa)
T23F2.2Uncharacterized protein. (1538 aa)
rpl-32Ribosomal Protein, Large subunit. (134 aa)
rpl-3960S ribosomal protein L39. (51 aa)
rps-340S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (247 aa)
eif-3.LEukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (538 aa)
rps-1340S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (151 aa)
rpl-2160S ribosomal protein L21; Belongs to the eukaryotic ribosomal protein eL21 family. (161 aa)
kxd-1KxDL domain-containing protein. (140 aa)
rpl-36.ARibosomal protein rpl-36.A; Belongs to the eukaryotic ribosomal protein eL42 family. (105 aa)
nbs-1FHA domain-containing protein. (362 aa)
rpl-1960S ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (198 aa)
rpl-3860S ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (70 aa)
rpl-14Ribosomal_L14e domain-containing protein. (135 aa)
C03H5.5Uncharacterized protein. (552 aa)
rpl-2960S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family. (62 aa)
eif-3.EEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (432 aa)
rps-29Ribosomal Protein, Small subunit. (56 aa)
rps-040S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. (276 aa)
rpl-2360S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. (140 aa)
rpl-260S ribosomal protein L8. (260 aa)
rpl-460S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family. (345 aa)
W01D2.1Ribosomal protein L37; Binds to the 23S rRNA. (92 aa)
rpl-7A60S ribosomal protein L7a; Belongs to the eukaryotic ribosomal protein eL8 family. (265 aa)
rpl-30Ribosomal_L7Ae domain-containing protein. (115 aa)
rps-20Ribosomal_S10 domain-containing protein. (117 aa)
rpl-3160S ribosomal protein L31. (122 aa)
ZK686.1Uncharacterized protein ZK686.1. (44 aa)
rpl-3560S ribosomal protein L35; Belongs to the universal ribosomal protein uL29 family. (123 aa)
rps-740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
Y94H6A.3Uncharacterized protein. (186 aa)
eif-3.IEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (327 aa)
Y73B3A.18annotation not available (234 aa)
rps-11Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family. (155 aa)
rla-2Ribosomal protein, Large subunit, Acidic (P1); Belongs to the eukaryotic ribosomal protein P1/P2 family. (110 aa)
rps-18Ribosomal Protein, Small subunit; Belongs to the universal ribosomal protein uS13 family. (154 aa)
eif-3.BEukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (725 aa)
rpl-1760S ribosomal protein L17. (187 aa)
Y48G8AL.7Uncharacterized protein. (239 aa)
rpl-4360S ribosomal protein L37a; Belongs to the eukaryotic ribosomal protein eL43 family. (91 aa)
rpl-1860S ribosomal protein L18. (188 aa)
rps-440S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (259 aa)
rps-2840S ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family. (65 aa)
eif-3.JEukaryotic Initiation Factor. (212 aa)
Y37E3.8Ribosomal_L18e/L15P domain-containing protein; Belongs to the universal ribosomal protein uL15 family. (145 aa)
rla-160S acidic ribosomal protein P1; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family. (111 aa)
rpl-2260S ribosomal protein L22. (130 aa)
egl-45Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1076 aa)
rpl-1360S ribosomal protein L13. (207 aa)
C37A2.760S acidic ribosomal protein P2; Plays an important role in the elongation step of protein synthesis. (107 aa)
eif-3.HEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (365 aa)
rpl-34Ribosomal Protein, Large subunit. (110 aa)
rps-240S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (272 aa)
rpl-2760S ribosomal protein L27; Component of the large ribosomal subunit. (136 aa)
rpl-3760S ribosomal protein L37; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (91 aa)
rpl-24.160S ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family. (159 aa)
pqn-24Prion-like-(Q/N-rich)-domain-bearing protein. (277 aa)
rps-10S10_plectin domain-containing protein. (149 aa)
D1081.6Toxin_TOLIP domain-containing protein. (247 aa)
eif-3.FEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (294 aa)
rpl-2060S ribosomal protein L18a; Belongs to the eukaryotic ribosomal protein eL20 family. (180 aa)
rpl-11.260S ribosomal protein L11-2; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throu [...] (196 aa)
rpl-1060S ribosomal protein L10. (214 aa)
rpl-3360S ribosomal protein L35a; Belongs to the eukaryotic ribosomal protein eL33 family. (124 aa)
rpl-360S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes; Belongs to the universal ribosomal protein uL3 family. (401 aa)
F13D11.43Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (343 aa)
F13H10.6Uncharacterized protein. (88 aa)
eif-3.GEukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (262 aa)
rla-060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (312 aa)
rpl-2660S ribosomal protein L26. (142 aa)
rps-2340S ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (143 aa)
spe-45Ig-like domain-containing protein. (492 aa)
rps-1540S ribosomal protein S15; Negatively regulates lifespan. (151 aa)
rps-2140S ribosomal protein S21. (88 aa)
rpl-3660S ribosomal protein L36; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL36 family. (104 aa)
rps-2640S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (117 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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