node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C29F9.5 | smo-1 | C29F9.5.1 | K12C11.2.1 | Uncharacterized protein. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.425 |
C29F9.6 | smo-1 | C29F9.6.1 | K12C11.2.1 | TAZ-type domain-containing protein. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.425 |
C49F5.5 | smo-1 | C49F5.5.1 | K12C11.2.1 | TAZ-type domain-containing protein. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.425 |
E04F6.15 | aptf-1 | E04F6.15.1 | K06A1.1.1 | Uncharacterized protein. | Transcription factor aptf-1; Transcription factor, which is required in the single sleep- active ring interneuron RIS for sleep-like behavioral quiescence induced by neuropeptide signaling in larvae. Regulates gene expression of sleep-inducing FMRFamide-like neuropeptide flp-11 in RIS. | 0.909 |
F22F1.3 | smo-1 | F22F1.3.1 | K12C11.2.1 | Uncharacterized protein. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.425 |
F29B9.8 | smo-1 | F29B9.8.2 | K12C11.2.1 | Uncharacterized protein. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.877 |
Y105E8B.7 | aptf-1 | Y105E8B.7.1 | K06A1.1.1 | Uncharacterized protein. | Transcription factor aptf-1; Transcription factor, which is required in the single sleep- active ring interneuron RIS for sleep-like behavioral quiescence induced by neuropeptide signaling in larvae. Regulates gene expression of sleep-inducing FMRFamide-like neuropeptide flp-11 in RIS. | 0.546 |
Y105E8B.7 | aptf-2 | Y105E8B.7.1 | Y62E10A.17b.1 | Uncharacterized protein. | TF_AP-2 domain-containing protein. | 0.546 |
Y105E8B.7 | aptf-3 | Y105E8B.7.1 | F28C6.2.1 | Uncharacterized protein. | TF_AP-2 domain-containing protein. | 0.546 |
Y105E8B.7 | aptf-4 | Y105E8B.7.1 | F28C6.1.1 | Uncharacterized protein. | TF_AP-2 domain-containing protein. | 0.546 |
Y105E8B.7 | gfl-1 | Y105E8B.7.1 | M04B2.3.1 | Uncharacterized protein. | GAS41-Like. | 0.589 |
ZK1010.10 | smo-1 | ZK1010.10.1 | K12C11.2.1 | TAZ-type domain-containing protein. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.425 |
aptf-1 | E04F6.15 | K06A1.1.1 | E04F6.15.1 | Transcription factor aptf-1; Transcription factor, which is required in the single sleep- active ring interneuron RIS for sleep-like behavioral quiescence induced by neuropeptide signaling in larvae. Regulates gene expression of sleep-inducing FMRFamide-like neuropeptide flp-11 in RIS. | Uncharacterized protein. | 0.909 |
aptf-1 | Y105E8B.7 | K06A1.1.1 | Y105E8B.7.1 | Transcription factor aptf-1; Transcription factor, which is required in the single sleep- active ring interneuron RIS for sleep-like behavioral quiescence induced by neuropeptide signaling in larvae. Regulates gene expression of sleep-inducing FMRFamide-like neuropeptide flp-11 in RIS. | Uncharacterized protein. | 0.546 |
aptf-1 | aptf-2 | K06A1.1.1 | Y62E10A.17b.1 | Transcription factor aptf-1; Transcription factor, which is required in the single sleep- active ring interneuron RIS for sleep-like behavioral quiescence induced by neuropeptide signaling in larvae. Regulates gene expression of sleep-inducing FMRFamide-like neuropeptide flp-11 in RIS. | TF_AP-2 domain-containing protein. | 0.684 |
aptf-1 | aptf-3 | K06A1.1.1 | F28C6.2.1 | Transcription factor aptf-1; Transcription factor, which is required in the single sleep- active ring interneuron RIS for sleep-like behavioral quiescence induced by neuropeptide signaling in larvae. Regulates gene expression of sleep-inducing FMRFamide-like neuropeptide flp-11 in RIS. | TF_AP-2 domain-containing protein. | 0.615 |
aptf-1 | aptf-4 | K06A1.1.1 | F28C6.1.1 | Transcription factor aptf-1; Transcription factor, which is required in the single sleep- active ring interneuron RIS for sleep-like behavioral quiescence induced by neuropeptide signaling in larvae. Regulates gene expression of sleep-inducing FMRFamide-like neuropeptide flp-11 in RIS. | TF_AP-2 domain-containing protein. | 0.598 |
aptf-1 | smo-1 | K06A1.1.1 | K12C11.2.1 | Transcription factor aptf-1; Transcription factor, which is required in the single sleep- active ring interneuron RIS for sleep-like behavioral quiescence induced by neuropeptide signaling in larvae. Regulates gene expression of sleep-inducing FMRFamide-like neuropeptide flp-11 in RIS. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.400 |
aptf-1 | ubc-9 | K06A1.1.1 | F29B9.6.2 | Transcription factor aptf-1; Transcription factor, which is required in the single sleep- active ring interneuron RIS for sleep-like behavioral quiescence induced by neuropeptide signaling in larvae. Regulates gene expression of sleep-inducing FMRFamide-like neuropeptide flp-11 in RIS. | SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like protein smo-1 from the aos-1-uba-2 E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase such as gei-17. Required to sumoylate the ETS transcription factor lin-1 and the Polycomb protein sop-2. Required for embryonic development, fertility, vulval morphogenesis and inhibition of vulval cell fates. Belongs to the ubiquitin-conjugating enzyme family. | 0.455 |
aptf-2 | Y105E8B.7 | Y62E10A.17b.1 | Y105E8B.7.1 | TF_AP-2 domain-containing protein. | Uncharacterized protein. | 0.546 |