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ubc-7 ubc-7 math-33 math-33 K08C9.7 K08C9.7 let-70 let-70 ubc-16 ubc-16 grd-16 grd-16 ubc-19 ubc-19 ubc-3 ubc-3 grd-15 grd-15 ubc-14 ubc-14 ubc-8 ubc-8 ubq-2 ubq-2 F52C6.12 F52C6.12 F52C6.2 F52C6.2 F52C6.3 F52C6.3 ubc-21 ubc-21 kxd-1 kxd-1 C28G1.10 C28G1.10 ubc-1 ubc-1 C35B1.2 C35B1.2 ubq-1 ubq-1 F34H10.1 F34H10.1 ubc-20 ubc-20 ubc-22 ubc-22 ubl-1 ubl-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ubc-7Probable ubiquitin-conjugating enzyme E2 7; Catalyzes the covalent attachment of ubiquitin to other proteins. (164 aa)
math-33Ubiquitin carboxyl-terminal hydrolase 7; Hydrolase that deubiquitinates target proteins. (1138 aa)
K08C9.7Uncharacterized protein. (154 aa)
let-70Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Mediates the selective degradation of short- lived and abnormal proteins. Plays a role in the DNA damage response. In particular, in response to ionizing radiation, associates with the E3 ubiquitin-protein ligase brc-1-brd-1 heterodimer on chromatin to activate E3-ubiquitin ligase activity of the heterodimer, and thus its DNA damage repair mechanisms ; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ubc-16Ubiquitin-conjugating enzyme E2 W; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (By similarity). Together with ubc-18, required for the ubiquitination of membranous organelles, and the removal of paternal mitochondria from early embryos. (152 aa)
grd-16GRounDhog (Hedgehog-like family). (404 aa)
ubc-19UBIQUITIN_CONJUGAT_2 domain-containing protein. (292 aa)
ubc-3UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (243 aa)
grd-15Ground-like domain-containing protein. (209 aa)
ubc-14UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
ubc-8UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (216 aa)
ubq-2Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] (128 aa)
F52C6.12UBIQUITIN_CONJUGAT_2 domain-containing protein. (78 aa)
F52C6.2Ubiquitin-like domain-containing protein. (228 aa)
F52C6.3Ubiquitin-like domain-containing protein. (197 aa)
ubc-21Probable ubiquitin-conjugating enzyme E2 21; Catalyzes the covalent attachment of ubiquitin to other proteins. (214 aa)
kxd-1KxDL domain-containing protein. (140 aa)
C28G1.10UBIQUITIN_CONJUGAT_2 domain-containing protein. (203 aa)
ubc-1Ubiquitin-conjugating enzyme E2 1; Catalyzes the covalent attachment of ubiquitin to other proteins; Belongs to the ubiquitin-conjugating enzyme family. (192 aa)
C35B1.2Uncharacterized protein. (562 aa)
ubq-1Ubiquitin-related; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degrad [...] (838 aa)
F34H10.1Probable ribosomal protein F34H10.1; Belongs to the eukaryotic ribosomal protein eS31 family. (142 aa)
ubc-20UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
ubc-22UBiquitin Conjugating enzyme. (182 aa)
ubl-1Ubiquitin-like protein 1-40S ribosomal protein S27a; In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family. (163 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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