STRINGSTRING
F52C6.3 F52C6.3 F52C6.2 F52C6.2 fce-2 fce-2 F34H10.1 F34H10.1 ubq-1 ubq-1 fntb-1 fntb-1 evl-20 evl-20 icmt-1 icmt-1 pdl-1 pdl-1 kxd-1 kxd-1 let-60 let-60 ubq-2 ubq-2 Y71G12A.4 Y71G12A.4 Y57G11C.33 Y57G11C.33 ral-1 ral-1 dhhc-2 dhhc-2 Y41E3.18 Y41E3.18 ced-9 ced-9 fnta-1 fnta-1 M01E11.1 M01E11.1 K08C9.7 K08C9.7 aho-3 aho-3 ubl-1 ubl-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F52C6.3Ubiquitin-like domain-containing protein. (197 aa)
F52C6.2Ubiquitin-like domain-containing protein. (228 aa)
fce-2CAAX prenyl protease 2 homolog; Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins; Belongs to the peptidase U48 family. (266 aa)
F34H10.1Probable ribosomal protein F34H10.1; Belongs to the eukaryotic ribosomal protein eS31 family. (142 aa)
ubq-1Ubiquitin-related; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degrad [...] (838 aa)
fntb-1Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. (401 aa)
evl-20ADP-ribosylation factor-like protein 2; GTP-binding protein that functions in embryogenesis, cytokinesis, germline development and microtubulule cytoskeleton dynamics. (184 aa)
icmt-1Protein-S-isoprenylcysteine O-methyltransferase. (295 aa)
pdl-1Phosphodiesterase delta-like protein. (159 aa)
kxd-1KxDL domain-containing protein. (140 aa)
let-60Ras protein let-60; The level of let-60 controls the switch between vulval and hypodermal cell fates during C.elegans vulval induction. May stimulate the guanine nucleotide exchange factor (GEF) activity of rap-1. Belongs to the small GTPase superfamily. Ras family. (184 aa)
ubq-2Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] (128 aa)
Y71G12A.4AB hydrolase-1 domain-containing protein. (468 aa)
Y57G11C.33Erf4 domain-containing protein. (177 aa)
ral-1RAL (Ras-related GTPase) homolog. (254 aa)
dhhc-2Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (404 aa)
Y41E3.18Hydrolase_4 domain-containing protein. (481 aa)
ced-9Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. (280 aa)
fnta-1FarNesylTransferase, Alpha subunit. (328 aa)
M01E11.1Protein-S-isoprenylcysteine O-methyltransferase. (293 aa)
K08C9.7Uncharacterized protein. (154 aa)
aho-3Alpha/beta hydrolase domain-containing protein aho-3; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins (By similarity). Acts in sensory neurons including AWC to regulate starvation-induced thermotaxis plasticity and salt learning behavior; Belongs to the AB hydrolase superfamily. ABHD17 family. (332 aa)
ubl-1Ubiquitin-like protein 1-40S ribosomal protein S27a; In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family. (163 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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