(15 nodes) Acyl-CoA dehydrogenase, C-terminal domain network (Caenorhabditis elegans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	acdh-12	Acyl CoA DeHydrogenase. (613 aa)
	ivd-1	Isovaleryl-CoA dehydrogenase. (419 aa)
	acdh-6	Probable acyl-CoA dehydrogenase 6; Belongs to the acyl-CoA dehydrogenase family. (408 aa)
	acdh-13	Acyl CoA DeHydrogenase. (617 aa)
	acdh-5	Acyl CoA DeHydrogenase. (442 aa)
	acdh-1	Acyl CoA DeHydrogenase. (427 aa)
	acdh-9	Acyl CoA DeHydrogenase. (409 aa)
	F54D5.7	Probable glutaryl-CoA dehydrogenase, mitochondrial. (409 aa)
	acdh-8	Acyl CoA DeHydrogenase. (412 aa)
	acdh-3	Acyl CoA DeHydrogenase. (419 aa)
	acds-10	ACaD (ACAD, acyl-CoA Dehydrogenase) Sequence homolog. (985 aa)
	acdh-10	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family. (417 aa)
	acdh-4	Acyl CoA DeHydrogenase. (385 aa)
	acdh-7	Acyl CoA DeHydrogenase. (412 aa)
	acdh-11	Acyl-CoA dehydrogenase family member 11; Promotes adaption to elevated temperatures by regulating expression of the lipid desaturase, fat-7. Binds selectively and with high affinity to fatty acids with chain lengths from C10 to C12 and prevents them from activating fat-7 expression mediated by the nuclear hormone receptor nhr-49, leading to low levels of membrane lipid desaturation and membrane fluidity for adaption to heat. (617 aa)

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F54D5.7	acdh-1	F54D5.7.2	C55B7.4a.1	Probable glutaryl-CoA dehydrogenase, mitochondrial.	Acyl CoA DeHydrogenase.	0.912
F54D5.7	acdh-10	F54D5.7.2	T08G2.3.2	Probable glutaryl-CoA dehydrogenase, mitochondrial.	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	0.920
F54D5.7	acdh-13	F54D5.7.2	C28C12.9.2	Probable glutaryl-CoA dehydrogenase, mitochondrial.	Acyl CoA DeHydrogenase.	0.461
F54D5.7	acdh-3	F54D5.7.2	K06A5.6.2	Probable glutaryl-CoA dehydrogenase, mitochondrial.	Acyl CoA DeHydrogenase.	0.917
F54D5.7	acdh-4	F54D5.7.2	T10E9.9b.1	Probable glutaryl-CoA dehydrogenase, mitochondrial.	Acyl CoA DeHydrogenase.	0.916
F54D5.7	acdh-7	F54D5.7.2	T25G12.5.1	Probable glutaryl-CoA dehydrogenase, mitochondrial.	Acyl CoA DeHydrogenase.	0.920
F54D5.7	acdh-8	F54D5.7.2	K05F1.3.1	Probable glutaryl-CoA dehydrogenase, mitochondrial.	Acyl CoA DeHydrogenase.	0.920
F54D5.7	acds-10	F54D5.7.2	K09H11.1.1	Probable glutaryl-CoA dehydrogenase, mitochondrial.	ACaD (ACAD, acyl-CoA Dehydrogenase) Sequence homolog.	0.643
acdh-1	F54D5.7	C55B7.4a.1	F54D5.7.2	Acyl CoA DeHydrogenase.	Probable glutaryl-CoA dehydrogenase, mitochondrial.	0.912
acdh-1	acdh-3	C55B7.4a.1	K06A5.6.2	Acyl CoA DeHydrogenase.	Acyl CoA DeHydrogenase.	0.902
acdh-1	acdh-4	C55B7.4a.1	T10E9.9b.1	Acyl CoA DeHydrogenase.	Acyl CoA DeHydrogenase.	0.901
acdh-10	F54D5.7	T08G2.3.2	F54D5.7.2	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Probable glutaryl-CoA dehydrogenase, mitochondrial.	0.920
acdh-10	acdh-11	T08G2.3.2	Y45F3A.3a.1	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Acyl-CoA dehydrogenase family member 11; Promotes adaption to elevated temperatures by regulating expression of the lipid desaturase, fat-7. Binds selectively and with high affinity to fatty acids with chain lengths from C10 to C12 and prevents them from activating fat-7 expression mediated by the nuclear hormone receptor nhr-49, leading to low levels of membrane lipid desaturation and membrane fluidity for adaption to heat.	0.551
acdh-10	acdh-12	T08G2.3.2	E04F6.5a.2	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Acyl CoA DeHydrogenase.	0.458
acdh-10	acdh-6	T08G2.3.2	C02D5.1.1	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Probable acyl-CoA dehydrogenase 6; Belongs to the acyl-CoA dehydrogenase family.	0.447
acdh-10	acdh-7	T08G2.3.2	T25G12.5.1	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Acyl CoA DeHydrogenase.	0.958
acdh-10	acdh-8	T08G2.3.2	K05F1.3.1	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Acyl CoA DeHydrogenase.	0.901
acdh-10	ivd-1	T08G2.3.2	C02B10.1.2	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Isovaleryl-CoA dehydrogenase.	0.428
acdh-11	acdh-10	Y45F3A.3a.1	T08G2.3.2	Acyl-CoA dehydrogenase family member 11; Promotes adaption to elevated temperatures by regulating expression of the lipid desaturase, fat-7. Binds selectively and with high affinity to fatty acids with chain lengths from C10 to C12 and prevents them from activating fat-7 expression mediated by the nuclear hormone receptor nhr-49, leading to low levels of membrane lipid desaturation and membrane fluidity for adaption to heat.	Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	0.551
acdh-11	acdh-12	Y45F3A.3a.1	E04F6.5a.2	Acyl-CoA dehydrogenase family member 11; Promotes adaption to elevated temperatures by regulating expression of the lipid desaturase, fat-7. Binds selectively and with high affinity to fatty acids with chain lengths from C10 to C12 and prevents them from activating fat-7 expression mediated by the nuclear hormone receptor nhr-49, leading to low levels of membrane lipid desaturation and membrane fluidity for adaption to heat.	Acyl CoA DeHydrogenase.	0.406