STRINGSTRING
cal-4 cal-4 his-1 his-1 cmd-1 cmd-1 his-67 his-67 epc-1 epc-1 his-10 his-10 his-26 his-26 phf-14 phf-14 his-14 his-14 his-46 his-46 B0563.7 B0563.7 cal-1 cal-1 cal-2 cal-2 his-37 his-37 his-50 his-50 his-31 his-31 his-64 his-64 cal-7 cal-7 lin-49 lin-49 his-5 his-5 his-56 his-56 his-60 his-60 chd-1 chd-1 K03A1.4 K03A1.4 his-38 his-38 his-18 his-18 his-28 his-28 cal-3 cal-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cal-4CALmodulin related genes. (236 aa)
his-1Histone H4. (103 aa)
cmd-1Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
his-67Histone H4. (103 aa)
epc-1Enhancer of PolyComb-like. (795 aa)
his-10Histone H4. (103 aa)
his-26Histone H4. (103 aa)
phf-14PHd Finger family. (599 aa)
his-14Histone H4. (103 aa)
his-46Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
B0563.7Uncharacterized calcium-binding protein B0563.7. (229 aa)
cal-1Calmodulin-like protein; This protein resembles calmodulin in sequence but possibly resembles troponin C in function. (180 aa)
cal-2CALmodulin related genes. (171 aa)
his-37Histone H4. (103 aa)
his-50Histone H4. (103 aa)
his-31Histone H4. (103 aa)
his-64Histone H4. (103 aa)
cal-7EF-hand domain-containing protein. (179 aa)
lin-49Protein lin-49; Essential protein required to maintain expression of homeotic genes egl-5 and mab-5. May play an analogous role to the trithorax Group (trxG) proteins. TrxG proteins form multiprotein complexes that are required to maintain the transcriptionally active state of homeotic genes throughout development. May act via a modification of chromatin. (1042 aa)
his-5Histone H4. (103 aa)
his-56Histone H4. (103 aa)
his-60Histone H4. (103 aa)
chd-1Chromodomain and Helicase Domain protein. (1461 aa)
K03A1.4EF-hand domain-containing protein. (184 aa)
his-38Histone H4. (103 aa)
his-18Histone H4. (103 aa)
his-28Histone H4. (103 aa)
cal-3CALmodulin related genes. (234 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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