Your Input: | |||||
hgrs-1 | Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. (729 aa) | ||||
stam-1 | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. (457 aa) | ||||
lov-1 | Location of vulva defective 1; Required for two aspects of male mating behavior: response to hermaphrodite contact and vulva location. Acts in the same pathway as pkd-2 and atp-2 in response behavior. May be required for ciliary targeting of pkd-2. (3284 aa) |