10 items (Caenorhabditis elegans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	smo-1	Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] (91 aa)
	cyb-2.1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (317 aa)
	fog-1	RRM domain-containing protein. (619 aa)
	cpb-2	Cytoplasmic polyadenylation element-binding protein 2; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). Not required for oogenesis. (570 aa)
	cpb-1	Cytoplasmic polyadenylation element-binding protein 1; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. Essential for progression through meiosis. Involved in spermatogenesis. (560 aa)
	ddx-23	DEAD boX helicase homolog; Belongs to the DEAD box helicase family. (730 aa)
	inf-1	Eukaryotic initiation factor 4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon; Belongs to the DEAD box helicase family. eIF4A subfamily. (402 aa)
	ddx-17	DEAD boX helicase homolog; Belongs to the DEAD box helicase family. (561 aa)
	cyb-2.2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (339 aa)
	cpb-3	Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis. (745 aa)

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cpb-1	cpb-2	C40H1.1.1	C30B5.3.1	Cytoplasmic polyadenylation element-binding protein 1; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. Essential for progression through meiosis. Involved in spermatogenesis.	Cytoplasmic polyadenylation element-binding protein 2; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). Not required for oogenesis.	0.672
cpb-1	cpb-3	C40H1.1.1	B0414.5.1	Cytoplasmic polyadenylation element-binding protein 1; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. Essential for progression through meiosis. Involved in spermatogenesis.	Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis.	0.830
cpb-1	cyb-2.1	C40H1.1.1	Y43E12A.1.1	Cytoplasmic polyadenylation element-binding protein 1; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. Essential for progression through meiosis. Involved in spermatogenesis.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.487
cpb-1	cyb-2.2	C40H1.1.1	H31G24.4.2	Cytoplasmic polyadenylation element-binding protein 1; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. Essential for progression through meiosis. Involved in spermatogenesis.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.508
cpb-1	fog-1	C40H1.1.1	Y54E10A.4b.1	Cytoplasmic polyadenylation element-binding protein 1; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. Essential for progression through meiosis. Involved in spermatogenesis.	RRM domain-containing protein.	0.691
cpb-2	cpb-1	C30B5.3.1	C40H1.1.1	Cytoplasmic polyadenylation element-binding protein 2; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). Not required for oogenesis.	Cytoplasmic polyadenylation element-binding protein 1; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. Essential for progression through meiosis. Involved in spermatogenesis.	0.672
cpb-2	cpb-3	C30B5.3.1	B0414.5.1	Cytoplasmic polyadenylation element-binding protein 2; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). Not required for oogenesis.	Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis.	0.683
cpb-2	cyb-2.1	C30B5.3.1	Y43E12A.1.1	Cytoplasmic polyadenylation element-binding protein 2; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). Not required for oogenesis.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.422
cpb-2	cyb-2.2	C30B5.3.1	H31G24.4.2	Cytoplasmic polyadenylation element-binding protein 2; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). Not required for oogenesis.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.462
cpb-2	fog-1	C30B5.3.1	Y54E10A.4b.1	Cytoplasmic polyadenylation element-binding protein 2; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). Not required for oogenesis.	RRM domain-containing protein.	0.604
cpb-3	cpb-1	B0414.5.1	C40H1.1.1	Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis.	Cytoplasmic polyadenylation element-binding protein 1; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. Essential for progression through meiosis. Involved in spermatogenesis.	0.830
cpb-3	cpb-2	B0414.5.1	C30B5.3.1	Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis.	Cytoplasmic polyadenylation element-binding protein 2; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). Not required for oogenesis.	0.683
cpb-3	cyb-2.1	B0414.5.1	Y43E12A.1.1	Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.692
cpb-3	cyb-2.2	B0414.5.1	H31G24.4.2	Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.702
cpb-3	ddx-17	B0414.5.1	F58E10.3a.5	Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis.	DEAD boX helicase homolog; Belongs to the DEAD box helicase family.	0.586
cpb-3	fog-1	B0414.5.1	Y54E10A.4b.1	Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis.	RRM domain-containing protein.	0.714
cyb-2.1	cpb-1	Y43E12A.1.1	C40H1.1.1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cytoplasmic polyadenylation element-binding protein 1; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. Essential for progression through meiosis. Involved in spermatogenesis.	0.487
cyb-2.1	cpb-2	Y43E12A.1.1	C30B5.3.1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cytoplasmic polyadenylation element-binding protein 2; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). Not required for oogenesis.	0.422
cyb-2.1	cpb-3	Y43E12A.1.1	B0414.5.1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis.	0.692
cyb-2.1	cyb-2.2	Y43E12A.1.1	H31G24.4.2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.946