node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
arl-8 | cup-5 | Y57G11C.13.1 | R13A5.1e.2 | Novel small G protein indispensable for equal chromosome segregation; Belongs to the small GTPase superfamily. Arf family. | PKD_channel domain-containing protein. | 0.498 |
arl-8 | rab-5 | Y57G11C.13.1 | F26H9.6.1 | Novel small G protein indispensable for equal chromosome segregation; Belongs to the small GTPase superfamily. Arf family. | RAB family. | 0.605 |
arl-8 | sand-1 | Y57G11C.13.1 | F41H10.11.2 | Novel small G protein indispensable for equal chromosome segregation; Belongs to the small GTPase superfamily. Arf family. | SAND endocytosis protein family. | 0.731 |
arl-8 | vps-34 | Y57G11C.13.1 | B0025.1a.1 | Novel small G protein indispensable for equal chromosome segregation; Belongs to the small GTPase superfamily. Arf family. | Phosphatidylinositol 3-kinase catalytic subunit type 3; Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Together with bec-1, mediates the production of phosphatidylinositol 3-phosphate on intracellular vesicles and thereby regulates membrane trafficking. Plays a role in endosome-to-Golgi retrograde transport of mig-14. Involved in clearance of apoptotic cell corpses by phagosomes. Phagosome maturation requires two sequential and non-overlapping pulses of phosphatidylinositol-3-phosphate (PI3P) on the vesicle surface which mediates recr [...] | 0.418 |
asp-1 | asp-3 | Y39B6A.20.2 | H22K11.1.1 | Aspartic protease 1; Aspartic protease, which is part of the necrosis cell death pathway. Promotes B.thuringiensis Cry6Aa stability by preventing its proteolysis by host gut proteases. Required for Cry6Aa-induced necrotic death of intestinal cells. Cry6Aa uptake into the host intestinal cells triggers an increase in intracellular Ca(2+) levels leading to lysosome rupture and to the subsequent release of asp-1 which leads to necrosis ; Belongs to the peptidase A1 family. | Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. | 0.926 |
asp-1 | asp-4 | Y39B6A.20.2 | R12H7.2.1 | Aspartic protease 1; Aspartic protease, which is part of the necrosis cell death pathway. Promotes B.thuringiensis Cry6Aa stability by preventing its proteolysis by host gut proteases. Required for Cry6Aa-induced necrotic death of intestinal cells. Cry6Aa uptake into the host intestinal cells triggers an increase in intracellular Ca(2+) levels leading to lysosome rupture and to the subsequent release of asp-1 which leads to necrosis ; Belongs to the peptidase A1 family. | Aspartic protease 4; Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. Belongs to the peptidase A1 family. | 0.530 |
asp-1 | lmp-1 | Y39B6A.20.2 | C03B1.12.1 | Aspartic protease 1; Aspartic protease, which is part of the necrosis cell death pathway. Promotes B.thuringiensis Cry6Aa stability by preventing its proteolysis by host gut proteases. Required for Cry6Aa-induced necrotic death of intestinal cells. Cry6Aa uptake into the host intestinal cells triggers an increase in intracellular Ca(2+) levels leading to lysosome rupture and to the subsequent release of asp-1 which leads to necrosis ; Belongs to the peptidase A1 family. | LAMP family protein lmp-1; Belongs to the LAMP family. | 0.526 |
asp-3 | asp-1 | H22K11.1.1 | Y39B6A.20.2 | Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. | Aspartic protease 1; Aspartic protease, which is part of the necrosis cell death pathway. Promotes B.thuringiensis Cry6Aa stability by preventing its proteolysis by host gut proteases. Required for Cry6Aa-induced necrotic death of intestinal cells. Cry6Aa uptake into the host intestinal cells triggers an increase in intracellular Ca(2+) levels leading to lysosome rupture and to the subsequent release of asp-1 which leads to necrosis ; Belongs to the peptidase A1 family. | 0.926 |
asp-3 | asp-4 | H22K11.1.1 | R12H7.2.1 | Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. | Aspartic protease 4; Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. Belongs to the peptidase A1 family. | 0.916 |
asp-3 | eea-1 | H22K11.1.1 | T10G3.5a.1 | Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. | FYVE-type domain-containing protein. | 0.439 |
asp-3 | lmp-1 | H22K11.1.1 | C03B1.12.1 | Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. | LAMP family protein lmp-1; Belongs to the LAMP family. | 0.500 |
asp-3 | rab-5 | H22K11.1.1 | F26H9.6.1 | Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. | RAB family. | 0.479 |
asp-3 | vps-34 | H22K11.1.1 | B0025.1a.1 | Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. | Phosphatidylinositol 3-kinase catalytic subunit type 3; Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Together with bec-1, mediates the production of phosphatidylinositol 3-phosphate on intracellular vesicles and thereby regulates membrane trafficking. Plays a role in endosome-to-Golgi retrograde transport of mig-14. Involved in clearance of apoptotic cell corpses by phagosomes. Phagosome maturation requires two sequential and non-overlapping pulses of phosphatidylinositol-3-phosphate (PI3P) on the vesicle surface which mediates recr [...] | 0.570 |
asp-4 | asp-1 | R12H7.2.1 | Y39B6A.20.2 | Aspartic protease 4; Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. Belongs to the peptidase A1 family. | Aspartic protease 1; Aspartic protease, which is part of the necrosis cell death pathway. Promotes B.thuringiensis Cry6Aa stability by preventing its proteolysis by host gut proteases. Required for Cry6Aa-induced necrotic death of intestinal cells. Cry6Aa uptake into the host intestinal cells triggers an increase in intracellular Ca(2+) levels leading to lysosome rupture and to the subsequent release of asp-1 which leads to necrosis ; Belongs to the peptidase A1 family. | 0.530 |
asp-4 | asp-3 | R12H7.2.1 | H22K11.1.1 | Aspartic protease 4; Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. Belongs to the peptidase A1 family. | Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. | 0.916 |
asp-4 | eea-1 | R12H7.2.1 | T10G3.5a.1 | Aspartic protease 4; Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. Belongs to the peptidase A1 family. | FYVE-type domain-containing protein. | 0.429 |
asp-4 | lmp-1 | R12H7.2.1 | C03B1.12.1 | Aspartic protease 4; Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. Belongs to the peptidase A1 family. | LAMP family protein lmp-1; Belongs to the LAMP family. | 0.497 |
asp-4 | rab-5 | R12H7.2.1 | F26H9.6.1 | Aspartic protease 4; Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. Belongs to the peptidase A1 family. | RAB family. | 0.517 |
asp-4 | vps-34 | R12H7.2.1 | B0025.1a.1 | Aspartic protease 4; Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. Belongs to the peptidase A1 family. | Phosphatidylinositol 3-kinase catalytic subunit type 3; Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Together with bec-1, mediates the production of phosphatidylinositol 3-phosphate on intracellular vesicles and thereby regulates membrane trafficking. Plays a role in endosome-to-Golgi retrograde transport of mig-14. Involved in clearance of apoptotic cell corpses by phagosomes. Phagosome maturation requires two sequential and non-overlapping pulses of phosphatidylinositol-3-phosphate (PI3P) on the vesicle surface which mediates recr [...] | 0.512 |
cup-5 | arl-8 | R13A5.1e.2 | Y57G11C.13.1 | PKD_channel domain-containing protein. | Novel small G protein indispensable for equal chromosome segregation; Belongs to the small GTPase superfamily. Arf family. | 0.498 |