node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ant-1.1 | ced-9 | T27E9.1a.1 | T07C4.8.1 | Adenine Nucleotide Translocator; Belongs to the mitochondrial carrier (TC 2.A.29) family. | Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. | 0.542 |
ant-1.3 | ant-1.4 | K01H12.2.1 | T01B11.4.1 | Mitochondrial adenine nucleotide translocase 1.3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | Mitochondrial adenine nucleotide translocase 1.4; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.605 |
ant-1.3 | gln-2 | K01H12.2.1 | K03H1.1.1 | Mitochondrial adenine nucleotide translocase 1.3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | Probable glutamine synthetase. | 0.457 |
ant-1.4 | ant-1.3 | T01B11.4.1 | K01H12.2.1 | Mitochondrial adenine nucleotide translocase 1.4; Belongs to the mitochondrial carrier (TC 2.A.29) family. | Mitochondrial adenine nucleotide translocase 1.3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.605 |
ant-1.4 | gln-2 | T01B11.4.1 | K03H1.1.1 | Mitochondrial adenine nucleotide translocase 1.4; Belongs to the mitochondrial carrier (TC 2.A.29) family. | Probable glutamine synthetase. | 0.459 |
atg-3 | atg-5 | Y55F3AM.4a.1 | Y71G12B.12a.1 | Autophagy-related protein 3. | Autophagy-related protein 5; Involved in autophagic vesicle formation (By similarity). Conjugation with lgg-3/ATG12, through a ubiquitin-like conjugating system involving atg-7 as an E1-like activating enzyme and atg-10 as an E2-like conjugating enzyme, is essential for its function (By similarity). Most likely a component of an atg-5-lgg-3-atg-16 complex that promotes autophagosome formation by associating with lgg-2, but not lgg-1, at the preautophagosomal membrane. Probably, as part of an atg-5-lgg-3-atg-16 complex, required for lgg-1 lipidation; the complex acts as an E3-like enzym [...] | 0.999 |
atg-3 | atg-7 | Y55F3AM.4a.1 | M7.5.1 | Autophagy-related protein 3. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | 0.999 |
atg-3 | ced-9 | Y55F3AM.4a.1 | T07C4.8.1 | Autophagy-related protein 3. | Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. | 0.451 |
atg-3 | lgg-3 | Y55F3AM.4a.1 | B0336.8.1 | Autophagy-related protein 3. | Ubiquitin-like protein atg-12; Ubiquitin-like protein involved in autophagy vesicles formation (By similarity). Conjugation with atg-5 through a ubiquitin- like conjugating system involving also atg-7 as an E1-like activating enzyme and atg-10 as an E2-like conjugating enzyme, is essential for its function (By similarity). Most likely a component of an atg-5-lgg- 3-atg-16 complex that promotes autophagosome formation by associating with lgg-2, but not lgg-1, at the preautophagosomal membrane. Probably, as part of an atg-5-lgg- 3-atg-16 complex, required for lgg-1 lipidation; the comple [...] | 0.999 |
atg-5 | atg-3 | Y71G12B.12a.1 | Y55F3AM.4a.1 | Autophagy-related protein 5; Involved in autophagic vesicle formation (By similarity). Conjugation with lgg-3/ATG12, through a ubiquitin-like conjugating system involving atg-7 as an E1-like activating enzyme and atg-10 as an E2-like conjugating enzyme, is essential for its function (By similarity). Most likely a component of an atg-5-lgg-3-atg-16 complex that promotes autophagosome formation by associating with lgg-2, but not lgg-1, at the preautophagosomal membrane. Probably, as part of an atg-5-lgg-3-atg-16 complex, required for lgg-1 lipidation; the complex acts as an E3-like enzym [...] | Autophagy-related protein 3. | 0.999 |
atg-5 | atg-7 | Y71G12B.12a.1 | M7.5.1 | Autophagy-related protein 5; Involved in autophagic vesicle formation (By similarity). Conjugation with lgg-3/ATG12, through a ubiquitin-like conjugating system involving atg-7 as an E1-like activating enzyme and atg-10 as an E2-like conjugating enzyme, is essential for its function (By similarity). Most likely a component of an atg-5-lgg-3-atg-16 complex that promotes autophagosome formation by associating with lgg-2, but not lgg-1, at the preautophagosomal membrane. Probably, as part of an atg-5-lgg-3-atg-16 complex, required for lgg-1 lipidation; the complex acts as an E3-like enzym [...] | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | 0.996 |
atg-5 | ced-9 | Y71G12B.12a.1 | T07C4.8.1 | Autophagy-related protein 5; Involved in autophagic vesicle formation (By similarity). Conjugation with lgg-3/ATG12, through a ubiquitin-like conjugating system involving atg-7 as an E1-like activating enzyme and atg-10 as an E2-like conjugating enzyme, is essential for its function (By similarity). Most likely a component of an atg-5-lgg-3-atg-16 complex that promotes autophagosome formation by associating with lgg-2, but not lgg-1, at the preautophagosomal membrane. Probably, as part of an atg-5-lgg-3-atg-16 complex, required for lgg-1 lipidation; the complex acts as an E3-like enzym [...] | Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. | 0.630 |
atg-5 | lgg-3 | Y71G12B.12a.1 | B0336.8.1 | Autophagy-related protein 5; Involved in autophagic vesicle formation (By similarity). Conjugation with lgg-3/ATG12, through a ubiquitin-like conjugating system involving atg-7 as an E1-like activating enzyme and atg-10 as an E2-like conjugating enzyme, is essential for its function (By similarity). Most likely a component of an atg-5-lgg-3-atg-16 complex that promotes autophagosome formation by associating with lgg-2, but not lgg-1, at the preautophagosomal membrane. Probably, as part of an atg-5-lgg-3-atg-16 complex, required for lgg-1 lipidation; the complex acts as an E3-like enzym [...] | Ubiquitin-like protein atg-12; Ubiquitin-like protein involved in autophagy vesicles formation (By similarity). Conjugation with atg-5 through a ubiquitin- like conjugating system involving also atg-7 as an E1-like activating enzyme and atg-10 as an E2-like conjugating enzyme, is essential for its function (By similarity). Most likely a component of an atg-5-lgg- 3-atg-16 complex that promotes autophagosome formation by associating with lgg-2, but not lgg-1, at the preautophagosomal membrane. Probably, as part of an atg-5-lgg- 3-atg-16 complex, required for lgg-1 lipidation; the comple [...] | 0.999 |
atg-7 | atg-3 | M7.5.1 | Y55F3AM.4a.1 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | Autophagy-related protein 3. | 0.999 |
atg-7 | atg-5 | M7.5.1 | Y71G12B.12a.1 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | Autophagy-related protein 5; Involved in autophagic vesicle formation (By similarity). Conjugation with lgg-3/ATG12, through a ubiquitin-like conjugating system involving atg-7 as an E1-like activating enzyme and atg-10 as an E2-like conjugating enzyme, is essential for its function (By similarity). Most likely a component of an atg-5-lgg-3-atg-16 complex that promotes autophagosome formation by associating with lgg-2, but not lgg-1, at the preautophagosomal membrane. Probably, as part of an atg-5-lgg-3-atg-16 complex, required for lgg-1 lipidation; the complex acts as an E3-like enzym [...] | 0.996 |
atg-7 | ced-9 | M7.5.1 | T07C4.8.1 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. | 0.603 |
atg-7 | lgg-3 | M7.5.1 | B0336.8.1 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | Ubiquitin-like protein atg-12; Ubiquitin-like protein involved in autophagy vesicles formation (By similarity). Conjugation with atg-5 through a ubiquitin- like conjugating system involving also atg-7 as an E1-like activating enzyme and atg-10 as an E2-like conjugating enzyme, is essential for its function (By similarity). Most likely a component of an atg-5-lgg- 3-atg-16 complex that promotes autophagosome formation by associating with lgg-2, but not lgg-1, at the preautophagosomal membrane. Probably, as part of an atg-5-lgg- 3-atg-16 complex, required for lgg-1 lipidation; the comple [...] | 0.999 |
ced-9 | ant-1.1 | T07C4.8.1 | T27E9.1a.1 | Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. | Adenine Nucleotide Translocator; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.542 |
ced-9 | atg-3 | T07C4.8.1 | Y55F3AM.4a.1 | Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. | Autophagy-related protein 3. | 0.451 |
ced-9 | atg-5 | T07C4.8.1 | Y71G12B.12a.1 | Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. | Autophagy-related protein 5; Involved in autophagic vesicle formation (By similarity). Conjugation with lgg-3/ATG12, through a ubiquitin-like conjugating system involving atg-7 as an E1-like activating enzyme and atg-10 as an E2-like conjugating enzyme, is essential for its function (By similarity). Most likely a component of an atg-5-lgg-3-atg-16 complex that promotes autophagosome formation by associating with lgg-2, but not lgg-1, at the preautophagosomal membrane. Probably, as part of an atg-5-lgg-3-atg-16 complex, required for lgg-1 lipidation; the complex acts as an E3-like enzym [...] | 0.630 |