STRINGSTRING
vps-60 vps-60 act-5 act-5 vps-24 vps-24 vps-28 vps-28 vps-20 vps-20 did-2 did-2 vps-36 vps-36 stam-1 stam-1 spas-1 spas-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
vps-60Related to yeast Vacuolar Protein Sorting factor. (217 aa)
act-5ACTin. (375 aa)
vps-24Related to yeast Vacuolar Protein Sorting factor. (208 aa)
vps-28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex, a regulator of vesicular trafficking process; Belongs to the VPS28 family. (210 aa)
vps-20Related to yeast Vacuolar Protein Sorting factor. (208 aa)
did-2Doa4-Independent Degradation, homologous to yeast Did2. (205 aa)
vps-36GLUE N-terminal domain-containing protein. (383 aa)
stam-1Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. (457 aa)
spas-1Probable spastin homolog spas-1; Severs microtubules, probably in an ATP-dependent fashion. Belongs to the AAA ATPase family. Spastin subfamily. (512 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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