STRINGSTRING
mec-3 mec-3 lin-11 lin-11 clp-7 clp-7 clp-6 clp-6 clp-3 clp-3 clp-4 clp-4 clp-10 clp-10 clp-9 clp-9 clp-2 clp-2 spi-1 spi-1 clp-8 clp-8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mec-3Mechanosensory protein 3; Specifies differentiation of the set of six touch receptor neurons. Binds cooperatively as a heterodimer with unc-86 to sites in the mec-3 gene promoter. (321 aa)
lin-11Protein lin-11; Probable transcription factor which is required for asymmetric division of vulval blast cells. Involved in olfactory plasticity probably by regulating the expression of transcription factor mbr-1 in RIF neurons. Plays a role in the chemorepulsive response toward ascaroside pheromones mediated by the ADL sensory neurons, probably by regulating E-box motif 5'-CANNTG-3' containing target genes in the ADL neurons. Plays a role in the differentiation of the ADL sensory neurons. (405 aa)
clp-7Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (778 aa)
clp-6Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (627 aa)
clp-3Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (752 aa)
clp-4Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (716 aa)
clp-10Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (634 aa)
clp-9Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (718 aa)
clp-2Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (805 aa)
spi-1Serine protease inhibitor 1 protein. (100 aa)
clp-8Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (646 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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