node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F32H5.1 | act-5 | F32H5.1.1 | T25C8.2.2 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | ACTin. | 0.692 |
F32H5.1 | asp-3 | F32H5.1.1 | H22K11.1.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. | 0.940 |
F32H5.1 | asp-4 | F32H5.1.1 | R12H7.2.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | Aspartic protease 4; Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. Belongs to the peptidase A1 family. | 0.934 |
F32H5.1 | atg-5 | F32H5.1.1 | Y71G12B.12a.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | Autophagy-related protein 5; Involved in autophagic vesicle formation (By similarity). Conjugation with lgg-3/ATG12, through a ubiquitin-like conjugating system involving atg-7 as an E1-like activating enzyme and atg-10 as an E2-like conjugating enzyme, is essential for its function (By similarity). Most likely a component of an atg-5-lgg-3-atg-16 complex that promotes autophagosome formation by associating with lgg-2, but not lgg-1, at the preautophagosomal membrane. Probably, as part of an atg-5-lgg-3-atg-16 complex, required for lgg-1 lipidation; the complex acts as an E3-like enzym [...] | 0.693 |
F32H5.1 | cpl-1 | F32H5.1.1 | T03E6.7a.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | Cathepsin L-like; Cysteine protease which plays an essential role in the degradation of proteins in lysosomes. During early embryogenesis, maternally required for the proteolytic processing of yolk proteins in platelets, a lysosome- like structure where a slow and controlled degradation of yolk proteins occurs. In the gonad, required for the clearance of apoptotic germ cells in the engulfing cell phagolysosomes. In embryos, required for the degradation of endocytic and autophagic cargos. In embryos, may play a role in the degradation of lipid-containing droplets. Required for larval de [...] | 0.978 |
F57F5.1 | act-5 | F57F5.1.1 | T25C8.2.2 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | ACTin. | 0.742 |
F57F5.1 | asp-3 | F57F5.1.1 | H22K11.1.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. | 0.980 |
F57F5.1 | asp-4 | F57F5.1.1 | R12H7.2.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | Aspartic protease 4; Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. Belongs to the peptidase A1 family. | 0.937 |
F57F5.1 | atg-5 | F57F5.1.1 | Y71G12B.12a.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | Autophagy-related protein 5; Involved in autophagic vesicle formation (By similarity). Conjugation with lgg-3/ATG12, through a ubiquitin-like conjugating system involving atg-7 as an E1-like activating enzyme and atg-10 as an E2-like conjugating enzyme, is essential for its function (By similarity). Most likely a component of an atg-5-lgg-3-atg-16 complex that promotes autophagosome formation by associating with lgg-2, but not lgg-1, at the preautophagosomal membrane. Probably, as part of an atg-5-lgg-3-atg-16 complex, required for lgg-1 lipidation; the complex acts as an E3-like enzym [...] | 0.693 |
F57F5.1 | cpl-1 | F57F5.1.1 | T03E6.7a.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | Cathepsin L-like; Cysteine protease which plays an essential role in the degradation of proteins in lysosomes. During early embryogenesis, maternally required for the proteolytic processing of yolk proteins in platelets, a lysosome- like structure where a slow and controlled degradation of yolk proteins occurs. In the gonad, required for the clearance of apoptotic germ cells in the engulfing cell phagolysosomes. In embryos, required for the degradation of endocytic and autophagic cargos. In embryos, may play a role in the degradation of lipid-containing droplets. Required for larval de [...] | 0.642 |
F57F5.1 | cpr-1 | F57F5.1.1 | C52E4.1.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | Gut-specific cysteine proteinase; Thiol protease. Has a role as a digestive enzyme. Belongs to the peptidase C1 family. | 0.670 |
F57F5.1 | cpr-5 | F57F5.1.1 | W07B8.5.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | Cathepsin B-like cysteine proteinase 5; Belongs to the peptidase C1 family. | 0.613 |
W07B8.4 | act-5 | W07B8.4a.1 | T25C8.2.2 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | ACTin. | 0.675 |
W07B8.4 | asp-3 | W07B8.4a.1 | H22K11.1.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. | 0.930 |
W07B8.4 | asp-4 | W07B8.4a.1 | R12H7.2.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | Aspartic protease 4; Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. Belongs to the peptidase A1 family. | 0.932 |
W07B8.4 | atg-5 | W07B8.4a.1 | Y71G12B.12a.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | Autophagy-related protein 5; Involved in autophagic vesicle formation (By similarity). Conjugation with lgg-3/ATG12, through a ubiquitin-like conjugating system involving atg-7 as an E1-like activating enzyme and atg-10 as an E2-like conjugating enzyme, is essential for its function (By similarity). Most likely a component of an atg-5-lgg-3-atg-16 complex that promotes autophagosome formation by associating with lgg-2, but not lgg-1, at the preautophagosomal membrane. Probably, as part of an atg-5-lgg-3-atg-16 complex, required for lgg-1 lipidation; the complex acts as an E3-like enzym [...] | 0.693 |
W07B8.4 | cpl-1 | W07B8.4a.1 | T03E6.7a.1 | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | Cathepsin L-like; Cysteine protease which plays an essential role in the degradation of proteins in lysosomes. During early embryogenesis, maternally required for the proteolytic processing of yolk proteins in platelets, a lysosome- like structure where a slow and controlled degradation of yolk proteins occurs. In the gonad, required for the clearance of apoptotic germ cells in the engulfing cell phagolysosomes. In embryos, required for the degradation of endocytic and autophagic cargos. In embryos, may play a role in the degradation of lipid-containing droplets. Required for larval de [...] | 0.557 |
act-5 | F32H5.1 | T25C8.2.2 | F32H5.1.1 | ACTin. | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | 0.692 |
act-5 | F57F5.1 | T25C8.2.2 | F57F5.1.1 | ACTin. | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | 0.742 |
act-5 | W07B8.4 | T25C8.2.2 | W07B8.4a.1 | ACTin. | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. | 0.675 |