STRINGSTRING
try-10 try-10 cpr-1 cpr-1 try-3 try-3 spp-10 spp-10 cpr-6 cpr-6 daf-7 daf-7 vps-33.1 vps-33.1 try-9 try-9 cpl-1 cpl-1 ttr-1 ttr-1 asp-3 asp-3 F57F5.1 F57F5.1 try-6 try-6 cpr-4 cpr-4 tag-196 tag-196 cpr-2 cpr-2 F32H5.1 F32H5.1 try-4 try-4 try-8 try-8 apy-1 apy-1 glb-1 glb-1 try-1 try-1 try-7 try-7 mif-1 mif-1 cpr-5 cpr-5 W07B8.4 W07B8.4 cpr-8 cpr-8 lbp-8 lbp-8 asp-2 asp-2 cpr-3 cpr-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
try-10Peptidase S1 domain-containing protein. (355 aa)
cpr-1Gut-specific cysteine proteinase; Thiol protease. Has a role as a digestive enzyme. Belongs to the peptidase C1 family. (329 aa)
try-3Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (313 aa)
spp-10SaPosin-like Protein family. (429 aa)
cpr-6Cathepsin B-like cysteine proteinase 6; Belongs to the peptidase C1 family. (379 aa)
daf-7Dauer larva development regulatory growth factor daf-7; May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. Involved in sensitivity to CO2 levels. (350 aa)
vps-33.1Vacuolar protein sorting-associated protein 33A; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act as a component of the putative HOPS endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE- mediated membrane fusion. The HOPS complex is proposed to be recruited to rab-7 on the late endosomal membrane and to regulate lat [...] (603 aa)
try-9Peptidase S1 domain-containing protein. (279 aa)
cpl-1Cathepsin L-like; Cysteine protease which plays an essential role in the degradation of proteins in lysosomes. During early embryogenesis, maternally required for the proteolytic processing of yolk proteins in platelets, a lysosome- like structure where a slow and controlled degradation of yolk proteins occurs. In the gonad, required for the clearance of apoptotic germ cells in the engulfing cell phagolysosomes. In embryos, required for the degradation of endocytic and autophagic cargos. In embryos, may play a role in the degradation of lipid-containing droplets. Required for larval de [...] (337 aa)
ttr-1Transthyretin-like protein 1. (156 aa)
asp-3Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. (398 aa)
F57F5.1Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (351 aa)
try-6Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (343 aa)
cpr-4Cathepsin B-like cysteine proteinase 4; Thiol protease which shows activity against the fluorogenic substrate z-Arg-Arg-AMC; Belongs to the peptidase C1 family. (335 aa)
tag-196Uncharacterized protein; Belongs to the peptidase C1 family. (477 aa)
cpr-2Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (326 aa)
F32H5.1Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (356 aa)
try-4Peptidase S1 domain-containing protein. (324 aa)
try-8Peptidase S1 domain-containing protein. (401 aa)
apy-1Apyrase apy-1; Hydrolyzes UDP and to a lesser extent GDP. By preventing the accumulation of NDP, may promote the reglucosylation of incompletely folded glycoproteins in the endoplasmic reticulum following the unfolded protein response. (355 aa)
glb-1Globin-like protein; May be a globin and may play a role in oxygen transport. (159 aa)
try-1Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (293 aa)
try-7Peptidase S1 domain-containing protein. (380 aa)
mif-1MIF (Macrophage migration Inhibitory Factor) related. (117 aa)
cpr-5Cathepsin B-like cysteine proteinase 5; Belongs to the peptidase C1 family. (344 aa)
W07B8.4Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (335 aa)
cpr-8Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (335 aa)
lbp-8FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
asp-2Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (429 aa)
cpr-3Cathepsin B-like cysteine proteinase 3; Belongs to the peptidase C1 family. (370 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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