6 items (Caenorhabditis elegans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	atg-7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. (647 aa)
	vps-36	GLUE N-terminal domain-containing protein. (383 aa)
	vps-25	Related to yeast Vacuolar Protein Sorting factor. (183 aa)
	atp-6	ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (199 aa)
	atg-2	Autophagy-related protein 2; Component of the epg-6/atg-2 complex, which is involved in the generation of autophagosomes from omegasomes and in the distribution of atg-9 and atg-13 during the autophagy-mediated degradation of protein aggregates. Involved in autophagy-mediated degradation of ribosomal RNA and ribosomal proteins in lysosomes, which is essential for maintaining nucleotide homeostasis. (2290 aa)
	vps-8	Vps8 domain-containing protein. (1259 aa)

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
atg-2	atg-7	M03A8.2.2	M7.5.1	Autophagy-related protein 2; Component of the epg-6/atg-2 complex, which is involved in the generation of autophagosomes from omegasomes and in the distribution of atg-9 and atg-13 during the autophagy-mediated degradation of protein aggregates. Involved in autophagy-mediated degradation of ribosomal RNA and ribosomal proteins in lysosomes, which is essential for maintaining nucleotide homeostasis.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	0.968
atg-7	atg-2	M7.5.1	M03A8.2.2	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	Autophagy-related protein 2; Component of the epg-6/atg-2 complex, which is involved in the generation of autophagosomes from omegasomes and in the distribution of atg-9 and atg-13 during the autophagy-mediated degradation of protein aggregates. Involved in autophagy-mediated degradation of ribosomal RNA and ribosomal proteins in lysosomes, which is essential for maintaining nucleotide homeostasis.	0.968
vps-25	vps-36	W02A11.2.2	F17C11.8.2	Related to yeast Vacuolar Protein Sorting factor.	GLUE N-terminal domain-containing protein.	0.999
vps-25	vps-8	W02A11.2.2	C42C1.4a.1	Related to yeast Vacuolar Protein Sorting factor.	Vps8 domain-containing protein.	0.799
vps-36	vps-25	F17C11.8.2	W02A11.2.2	GLUE N-terminal domain-containing protein.	Related to yeast Vacuolar Protein Sorting factor.	0.999
vps-36	vps-8	F17C11.8.2	C42C1.4a.1	GLUE N-terminal domain-containing protein.	Vps8 domain-containing protein.	0.864
vps-8	vps-25	C42C1.4a.1	W02A11.2.2	Vps8 domain-containing protein.	Related to yeast Vacuolar Protein Sorting factor.	0.799
vps-8	vps-36	C42C1.4a.1	F17C11.8.2	Vps8 domain-containing protein.	GLUE N-terminal domain-containing protein.	0.864