STRINGSTRING
acdh-13 acdh-13 acdh-5 acdh-5 acdh-1 acdh-1 aagr-1 aagr-1 eif-2A eif-2A acdh-12 acdh-12 acdh-9 acdh-9 snt-1 snt-1 gpd-4 gpd-4 ubr-5 ubr-5 agr-1 agr-1 snt-2 snt-2 gln-2 gln-2 acdh-8 acdh-8 acdh-3 acdh-3 gpd-3 gpd-3 gpd-2 gpd-2 R07H5.8 R07H5.8 acdh-10 acdh-10 gpd-1 gpd-1 acdh-4 acdh-4 acdh-7 acdh-7 bbs-1 bbs-1 acdh-2 acdh-2 ubr-1 ubr-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acdh-13Acyl CoA DeHydrogenase. (617 aa)
acdh-5Acyl CoA DeHydrogenase. (442 aa)
acdh-1Acyl CoA DeHydrogenase. (427 aa)
aagr-1P-type domain-containing protein; Belongs to the glycosyl hydrolase 31 family. (936 aa)
eif-2AEukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner; Belongs to the WD repeat EIF2A family. (570 aa)
acdh-12Acyl CoA DeHydrogenase. (613 aa)
acdh-9Acyl CoA DeHydrogenase. (409 aa)
snt-1Synaptotagmin-1; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone (By similarity). Involved in necrotic cell death. (443 aa)
gpd-4Glyceraldehyde-3-phosphate dehydrogenase 4. (341 aa)
ubr-5UBR E3 ubiquitin ligase homolog. (2944 aa)
agr-1AGRin (Synaptic protein) homolog family member. (1473 aa)
snt-2Synaptotagmin 2; Ca(2+) sensor involved in Ca(2+)-dependent secretion of the nlp-40 neuropeptide from intestinal cells. Involved in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds. (369 aa)
gln-2Probable glutamine synthetase. (367 aa)
acdh-8Acyl CoA DeHydrogenase. (412 aa)
acdh-3Acyl CoA DeHydrogenase. (419 aa)
gpd-3Glyceraldehyde-3-phosphate dehydrogenase 3. (341 aa)
gpd-2Glyceraldehyde-3-phosphate dehydrogenase 2. (341 aa)
R07H5.8PfkB domain-containing protein. (342 aa)
acdh-10Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family. (417 aa)
gpd-1Glyceraldehyde-3-phosphate dehydrogenase 1. (341 aa)
acdh-4Acyl CoA DeHydrogenase. (385 aa)
acdh-7Acyl CoA DeHydrogenase. (412 aa)
bbs-1Bardet-Biedl syndrome 1 protein homolog; Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for proper BBSome complex assembly and its ciliary localization. Required for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins along the ciliary axoneme. (576 aa)
acdh-2Acyl CoA DeHydrogenase. (386 aa)
ubr-1E3 ubiquitin-protein ligase ubr-1; E3 ubiquitin-protein ligase which is a component of the N-end rule pathway (By similarity). Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N- end rule, leading to their ubiquitination and subsequent degradation (By similarity). In complex with ced-3, required for the ced-3-mediated cleavage and subsequent degradation of the heterochronic protein lin-28 to regulate seam cell fate patterning during larval development. Negatively regulates glutamate metabolism through the aspartate aminotrans [...] (2058 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.