STRINGSTRING
mvb-12 mvb-12 tsg-101 tsg-101 spas-1 spas-1 vps-37 vps-37 bro-1 bro-1 spg-20 spg-20 sdn-1 sdn-1 clp-2 clp-2 act-5 act-5 vps-4 vps-4 vps-28 vps-28
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mvb-12MVB (Yeast MultiVesicular Body sorting factor) related. (277 aa)
tsg-101Tumor Susceptibility Gene homolog. (425 aa)
spas-1Probable spastin homolog spas-1; Severs microtubules, probably in an ATP-dependent fashion. Belongs to the AAA ATPase family. Spastin subfamily. (512 aa)
vps-37VPS37 C-terminal domain-containing protein. (234 aa)
bro-1BROther (Drosophila tx factor partner) homolog. (152 aa)
spg-20MIT domain-containing protein. (476 aa)
sdn-1Probable syndecan; Cell surface proteoglycan that bears heparan sulfate (By similarity). Required for correct mitotic spindle orientation of the ABar blastomere division plane and this may be through modulation of astral microtubule array, and in association with the wnt-signaling proteins mig-5 and dsh-2. Involved in the migration of AQR and PQR neurons, which descend from the Q neuroblasts. Promotes the axon guidance of D-type motor neurons. (288 aa)
clp-2Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (805 aa)
act-5ACTin. (375 aa)
vps-4Related to yeast Vacuolar Protein Sorting factor; Belongs to the AAA ATPase family. (430 aa)
vps-28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex, a regulator of vesicular trafficking process; Belongs to the VPS28 family. (210 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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