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alh-7 alh-7 sox-2 sox-2 alh-4 alh-4 alh-5 alh-5 act-5 act-5 alh-12 alh-12 let-756 let-756 alh-10 alh-10 alh-11 alh-11 alh-2 alh-2 alh-6 alh-6 alh-1 alh-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
alh-7Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (493 aa)
sox-2Transcription factor sox-2; Probable transcription factor that regulates the lineage progression of embryonic blast cells and controls the postmitotic specification and differentiation of neurons. Cooperates with additional factors to direct the differentiation of the olfactory neurons, functioning with the transcription factor ceh-36 to specify AWC neurons and with the LIM homeodomain factor lim-4 to suppress AWC terminal differentiation and promote AWB neuron differentiation. Plays a role in the terminal differentiation of glutamatergic and cholinergic neurons. Required for natural r [...] (283 aa)
alh-4Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (494 aa)
alh-5Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (437 aa)
act-5ACTin. (375 aa)
alh-12Aldedh domain-containing protein. (499 aa)
let-756Protein let-756; Required for larval development. Probably by binding receptor egl-15, regulates negatively membrane protrusion from body wall muscles during larval development. (425 aa)
alh-10Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (506 aa)
alh-11Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (687 aa)
alh-2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (514 aa)
alh-6Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (563 aa)
alh-1Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (510 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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