STRINGSTRING
acs-2 acs-2 sdha-1 sdha-1 icl-1 icl-1 lys-8 lys-8 ech-1.1 ech-1.1 acbp-1 acbp-1 ech-9 ech-9 cpt-5 cpt-5 fat-7 fat-7 lbp-3 lbp-3 lys-4 lys-4 nhr-49 nhr-49 lbp-7 lbp-7 lbp-8 lbp-8 fat-6 fat-6 fat-2 fat-2 fat-5 fat-5 fat-1 fat-1 glp-4 glp-4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acs-2Fatty Acid CoA Synthetase family. (618 aa)
sdha-1Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (646 aa)
icl-1Bifunctional glyoxylate cycle protein; In the C-terminal section; belongs to the malate synthase family. (968 aa)
lys-8LYSozyme. (286 aa)
ech-1.1Enoyl-CoA Hydratase. (755 aa)
acbp-1Acyl-CoA-binding protein homolog 1; Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. (86 aa)
ech-9Enoyl-CoA Hydratase. (434 aa)
cpt-5Carn_acyltransf domain-containing protein. (735 aa)
fat-7Delta(9)-fatty-acid desaturase fat-7; Delta(9)-fatty-acid desaturase that acts preferentially on stearoyl-CoA. Also acts on vaccenyl-coA, heptadecanyol-CoA, and palmitoyl-CoA. (338 aa)
lbp-3Fatty acid-binding protein homolog 3; May play a role in sequestering potentially toxic fatty acids and their peroxidation products, or it may be involved in the maintenance of the impermeable lipid layer of the eggshell. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (165 aa)
lys-4LYSozyme. (214 aa)
nhr-49Nuclear hormone receptor family member nhr-49; Orphan nuclear receptor. Regulates expression of lipid desaturase, fat-7 ; Belongs to the nuclear hormone receptor family. (501 aa)
lbp-7Fatty acid-binding protein homolog 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
lbp-8FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
fat-6Delta(9)-fatty-acid desaturase fat-6; Delta(9)-fatty-acid desaturase that acts preferentially on stearoyl-CoA. Also acts on vaccenyl-coA and heptadecanyol-CoA. Belongs to the fatty acid desaturase type 1 family. (339 aa)
fat-2Delta(12) fatty acid desaturase fat-2; Catalyzes the desaturation of oleic acid (Delta(9)-18:1, or C18:1(n-9)) to linoleic acid (Delta(9,12)-18:2, or C18:2(n-6)). This desaturation event is essential for the synthesis of longer chain polyunsaturated fatty acids (PUFAs) such as arachidonic acid (AA, or C20:4(n-6)) and eicosapentaenoic acid (EPA, or C20:5(n-3)). (376 aa)
fat-5Delta(9)-fatty-acid desaturase fat-5; Delta(9)-fatty-acid desaturase that acts preferentially on palmitoyl-CoA. Also acts on pentadecanoyl-coA and myristoyl-CoA. (333 aa)
fat-1Omega-3 fatty acid desaturase fat-1; Omega-3 fatty acid desaturase that acts on a range of substrates. Catalyzes the desaturation of linolenic acid (18:2n-6), dihomo-gamma-linoleic acid (DHGLA) (20:3n-6), and arachidonic acid (20:4n-6), to generate gamma linolenic acid (18:3n-3), eicosatetraenoic acid (20:4n-3) and eicosapentaenoic acid (20:5n-3) respectively. Although the enzyme has been suggested to act on glycerolipids, the precise nature of the fatty acid substrate is unknown. (402 aa)
glp-4Valine--tRNA ligase. (1050 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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