STRINGSTRING
hmgs-1 hmgs-1 hmgr-1 hmgr-1 kat-1 kat-1 T02G5.7 T02G5.7 idi-1 idi-1 tdc-1 tdc-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hmgs-1Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (462 aa)
hmgr-13-hydroxy-3-methylglutaryl coenzyme A reductase. (550 aa)
kat-1Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
T02G5.7Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
idi-1Nudix hydrolase domain-containing protein. (236 aa)
tdc-1Tyrosine decarboxylase; Required for the decarboxylation of tyrosine to tyramine, a precursor of octopamine but probably also itself a neurotransmitter. Involved in the regulation of egg laying, which is inhibited by tyramine. Also involved in controlling locomotion and head movements. Due to its involvement in octopamine biosynthesis, also required for crtc-1-dependent regulation of AMPK-mediated longevity which requires octopamine signaling ; Belongs to the group II decarboxylase family. (705 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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