node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
T02G5.7 | hmgr-1 | T02G5.7.1 | F08F8.2.1 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.694 |
T02G5.7 | hmgs-1 | T02G5.7.1 | F25B4.6.1 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.999 |
T02G5.7 | idi-1 | T02G5.7.1 | K06H7.9.1 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Nudix hydrolase domain-containing protein. | 0.858 |
T02G5.7 | kat-1 | T02G5.7.1 | T02G5.8.2 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | 0.912 |
hmgr-1 | T02G5.7 | F08F8.2.1 | T02G5.7.1 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.694 |
hmgr-1 | hmgs-1 | F08F8.2.1 | F25B4.6.1 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.999 |
hmgr-1 | idi-1 | F08F8.2.1 | K06H7.9.1 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Nudix hydrolase domain-containing protein. | 0.979 |
hmgr-1 | kat-1 | F08F8.2.1 | T02G5.8.2 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | 0.657 |
hmgs-1 | T02G5.7 | F25B4.6.1 | T02G5.7.1 | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.999 |
hmgs-1 | hmgr-1 | F25B4.6.1 | F08F8.2.1 | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.999 |
hmgs-1 | idi-1 | F25B4.6.1 | K06H7.9.1 | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Nudix hydrolase domain-containing protein. | 0.981 |
hmgs-1 | kat-1 | F25B4.6.1 | T02G5.8.2 | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | 0.999 |
idi-1 | T02G5.7 | K06H7.9.1 | T02G5.7.1 | Nudix hydrolase domain-containing protein. | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.858 |
idi-1 | hmgr-1 | K06H7.9.1 | F08F8.2.1 | Nudix hydrolase domain-containing protein. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.979 |
idi-1 | hmgs-1 | K06H7.9.1 | F25B4.6.1 | Nudix hydrolase domain-containing protein. | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.981 |
idi-1 | kat-1 | K06H7.9.1 | T02G5.8.2 | Nudix hydrolase domain-containing protein. | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | 0.755 |
kat-1 | T02G5.7 | T02G5.8.2 | T02G5.7.1 | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.912 |
kat-1 | hmgr-1 | T02G5.8.2 | F08F8.2.1 | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.657 |
kat-1 | hmgs-1 | T02G5.8.2 | F25B4.6.1 | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.999 |
kat-1 | idi-1 | T02G5.8.2 | K06H7.9.1 | Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family. | Nudix hydrolase domain-containing protein. | 0.755 |