node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Y37B11A.2 | him-14 | Y37B11A.2a.1 | ZK1127.11.1 | DNA polymerase. | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | 0.450 |
Y37B11A.2 | pola-1 | Y37B11A.2a.1 | Y47D3A.29b.1 | DNA polymerase. | DNA polymerase. | 0.771 |
dpy-11 | dpy-17 | F46E10.9.2 | F54D8.1.1 | Thioredoxin domain-containing protein. | Col_cuticle_N domain-containing protein. | 0.664 |
dpy-11 | lon-2 | F46E10.9.2 | C39E6.1.1 | Thioredoxin domain-containing protein. | LONg; Belongs to the glypican family. | 0.699 |
dpy-11 | rol-6 | F46E10.9.2 | T01B7.7.2 | Thioredoxin domain-containing protein. | Cuticle collagen rol-6; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Involved in body morphogenesis. | 0.425 |
dpy-11 | unc-32 | F46E10.9.2 | ZK637.8a.1 | Thioredoxin domain-containing protein. | Probable V-type proton ATPase 116 kDa subunit a; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (Probable). Regulates the size of gut granules during embryonic development. | 0.563 |
dpy-11 | unc-4 | F46E10.9.2 | F26C11.2.1 | Thioredoxin domain-containing protein. | Homeobox protein unc-4; Transcription factor that regulates synaptic specificity. Determines the pattern of synaptic input to VA motor neurons. Acts together with unc-37 by repressing the expression of VB-specific genes such as ceh-12, thereby preventing the adoption of VB motor neurons. Has no role in axonal guidance or outgrowth. Belongs to the paired homeobox family. Unc-4 subfamily. | 0.504 |
dpy-17 | dpy-11 | F54D8.1.1 | F46E10.9.2 | Col_cuticle_N domain-containing protein. | Thioredoxin domain-containing protein. | 0.664 |
dpy-17 | unc-32 | F54D8.1.1 | ZK637.8a.1 | Col_cuticle_N domain-containing protein. | Probable V-type proton ATPase 116 kDa subunit a; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (Probable). Regulates the size of gut granules during embryonic development. | 0.853 |
him-14 | Y37B11A.2 | ZK1127.11.1 | Y37B11A.2a.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | DNA polymerase. | 0.450 |
him-14 | him-8 | ZK1127.11.1 | T07G12.12a.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | C2H2-type domain-containing protein. | 0.555 |
him-14 | pola-1 | ZK1127.11.1 | Y47D3A.29b.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | DNA polymerase. | 0.426 |
him-8 | him-14 | T07G12.12a.1 | ZK1127.11.1 | C2H2-type domain-containing protein. | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | 0.555 |
him-8 | rol-6 | T07G12.12a.1 | T01B7.7.2 | C2H2-type domain-containing protein. | Cuticle collagen rol-6; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Involved in body morphogenesis. | 0.663 |
him-8 | unc-32 | T07G12.12a.1 | ZK637.8a.1 | C2H2-type domain-containing protein. | Probable V-type proton ATPase 116 kDa subunit a; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (Probable). Regulates the size of gut granules during embryonic development. | 0.547 |
let-60 | lin-1 | ZK792.6.1 | C37F5.1a.1 | Ras protein let-60; The level of let-60 controls the switch between vulval and hypodermal cell fates during C.elegans vulval induction. May stimulate the guanine nucleotide exchange factor (GEF) activity of rap-1. Belongs to the small GTPase superfamily. Ras family. | ETS domain-containing protein. | 0.868 |
let-60 | lin-31 | ZK792.6.1 | K10G6.1.1 | Ras protein let-60; The level of let-60 controls the switch between vulval and hypodermal cell fates during C.elegans vulval induction. May stimulate the guanine nucleotide exchange factor (GEF) activity of rap-1. Belongs to the small GTPase superfamily. Ras family. | Protein lin-31; Lin-31 regulates how vulval precursor cells choose their fate. It helps specify three alternative cell fates in vulval development. | 0.807 |
let-60 | rol-6 | ZK792.6.1 | T01B7.7.2 | Ras protein let-60; The level of let-60 controls the switch between vulval and hypodermal cell fates during C.elegans vulval induction. May stimulate the guanine nucleotide exchange factor (GEF) activity of rap-1. Belongs to the small GTPase superfamily. Ras family. | Cuticle collagen rol-6; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Involved in body morphogenesis. | 0.433 |
lin-1 | let-60 | C37F5.1a.1 | ZK792.6.1 | ETS domain-containing protein. | Ras protein let-60; The level of let-60 controls the switch between vulval and hypodermal cell fates during C.elegans vulval induction. May stimulate the guanine nucleotide exchange factor (GEF) activity of rap-1. Belongs to the small GTPase superfamily. Ras family. | 0.868 |
lin-1 | lin-31 | C37F5.1a.1 | K10G6.1.1 | ETS domain-containing protein. | Protein lin-31; Lin-31 regulates how vulval precursor cells choose their fate. It helps specify three alternative cell fates in vulval development. | 0.893 |