node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Y73B6BL.12 | act-5 | Y73B6BL.12.1 | T25C8.2.2 | Thioredoxin; Belongs to the thioredoxin family. | ACTin. | 0.668 |
Y73B6BL.12 | nsy-1 | Y73B6BL.12.1 | F59A6.1a.1 | Thioredoxin; Belongs to the thioredoxin family. | Mitogen-activated protein kinase kinase kinase nsy-1; Serine/threonine-protein kinase which, by phosphorylating and activating sek-1, plays an important role in the activation of the p38 pathway also composed of the downstream effectors sek-1 and pmk-1. Downstream of CaMKII unc-43 and adapter protein tir-1, plays a role in determining asymmetric cell fates in olfactory AWC neurons during neuronal development. Activation results in the repression of odorant receptor str-2 expression in one of the 2 AWC neurons. Involved in resistance to pathogenic Gram-positive and Gram-negative bacteri [...] | 0.963 |
Y73B6BL.12 | prdx-2 | Y73B6BL.12.1 | F09E5.15c.1 | Thioredoxin; Belongs to the thioredoxin family. | Thioredoxin domain-containing protein. | 0.922 |
Y73B6BL.12 | prdx-6 | Y73B6BL.12.1 | Y38C1AA.11.2 | Thioredoxin; Belongs to the thioredoxin family. | Thioredoxin domain-containing protein. | 0.842 |
Y73B6BL.12 | trx-4 | Y73B6BL.12.1 | Y44E3A.3.1 | Thioredoxin; Belongs to the thioredoxin family. | Thioredoxin; Belongs to the thioredoxin family. | 0.621 |
act-5 | Y73B6BL.12 | T25C8.2.2 | Y73B6BL.12.1 | ACTin. | Thioredoxin; Belongs to the thioredoxin family. | 0.668 |
act-5 | cdk-4 | T25C8.2.2 | F18H3.5b.1 | ACTin. | Cyclin-dependent kinase 4 homolog; Serine/threonine-protein kinase which, in association with cyclin D-like protein cyd-1, is required for the progression through the G1 phase of the cell cycle during postembryonic development by phosphorylating and inhibiting lin-35 and fzr-1. In complex with cyd-1, involved in sex determination during gonadogenesis by regulating the asymmetric division of the somatic gonadal precursor cell (SGP). | 0.476 |
act-5 | cya-1 | T25C8.2.2 | ZK507.6.1 | ACTin. | G2/mitotic-specific cyclin-A1; Involved in the control of the cell cycle after S phase. May bind to and activate cdk-1 and/or cdk-2 to promote cell cycle progression. Necessary for embryogenesis. Belongs to the cyclin family. Cyclin AB subfamily. | 0.552 |
act-5 | cya-2 | T25C8.2.2 | F59H6.7.1 | ACTin. | CYCLIN domain-containing protein; Belongs to the cyclin family. | 0.554 |
act-5 | prdx-2 | T25C8.2.2 | F09E5.15c.1 | ACTin. | Thioredoxin domain-containing protein. | 0.458 |
act-5 | trx-4 | T25C8.2.2 | Y44E3A.3.1 | ACTin. | Thioredoxin; Belongs to the thioredoxin family. | 0.684 |
cdc-5L | pola-1 | D1081.8.1 | Y47D3A.29b.1 | Cell Division Cycle related. | DNA polymerase. | 0.451 |
cdk-4 | act-5 | F18H3.5b.1 | T25C8.2.2 | Cyclin-dependent kinase 4 homolog; Serine/threonine-protein kinase which, in association with cyclin D-like protein cyd-1, is required for the progression through the G1 phase of the cell cycle during postembryonic development by phosphorylating and inhibiting lin-35 and fzr-1. In complex with cyd-1, involved in sex determination during gonadogenesis by regulating the asymmetric division of the somatic gonadal precursor cell (SGP). | ACTin. | 0.476 |
cdk-4 | cya-1 | F18H3.5b.1 | ZK507.6.1 | Cyclin-dependent kinase 4 homolog; Serine/threonine-protein kinase which, in association with cyclin D-like protein cyd-1, is required for the progression through the G1 phase of the cell cycle during postembryonic development by phosphorylating and inhibiting lin-35 and fzr-1. In complex with cyd-1, involved in sex determination during gonadogenesis by regulating the asymmetric division of the somatic gonadal precursor cell (SGP). | G2/mitotic-specific cyclin-A1; Involved in the control of the cell cycle after S phase. May bind to and activate cdk-1 and/or cdk-2 to promote cell cycle progression. Necessary for embryogenesis. Belongs to the cyclin family. Cyclin AB subfamily. | 0.983 |
cdk-4 | cya-2 | F18H3.5b.1 | F59H6.7.1 | Cyclin-dependent kinase 4 homolog; Serine/threonine-protein kinase which, in association with cyclin D-like protein cyd-1, is required for the progression through the G1 phase of the cell cycle during postembryonic development by phosphorylating and inhibiting lin-35 and fzr-1. In complex with cyd-1, involved in sex determination during gonadogenesis by regulating the asymmetric division of the somatic gonadal precursor cell (SGP). | CYCLIN domain-containing protein; Belongs to the cyclin family. | 0.973 |
cdk-4 | pcn-1 | F18H3.5b.1 | W03D2.4.1 | Cyclin-dependent kinase 4 homolog; Serine/threonine-protein kinase which, in association with cyclin D-like protein cyd-1, is required for the progression through the G1 phase of the cell cycle during postembryonic development by phosphorylating and inhibiting lin-35 and fzr-1. In complex with cyd-1, involved in sex determination during gonadogenesis by regulating the asymmetric division of the somatic gonadal precursor cell (SGP). | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.626 |
cdk-4 | pola-1 | F18H3.5b.1 | Y47D3A.29b.1 | Cyclin-dependent kinase 4 homolog; Serine/threonine-protein kinase which, in association with cyclin D-like protein cyd-1, is required for the progression through the G1 phase of the cell cycle during postembryonic development by phosphorylating and inhibiting lin-35 and fzr-1. In complex with cyd-1, involved in sex determination during gonadogenesis by regulating the asymmetric division of the somatic gonadal precursor cell (SGP). | DNA polymerase. | 0.484 |
cya-1 | act-5 | ZK507.6.1 | T25C8.2.2 | G2/mitotic-specific cyclin-A1; Involved in the control of the cell cycle after S phase. May bind to and activate cdk-1 and/or cdk-2 to promote cell cycle progression. Necessary for embryogenesis. Belongs to the cyclin family. Cyclin AB subfamily. | ACTin. | 0.552 |
cya-1 | cdk-4 | ZK507.6.1 | F18H3.5b.1 | G2/mitotic-specific cyclin-A1; Involved in the control of the cell cycle after S phase. May bind to and activate cdk-1 and/or cdk-2 to promote cell cycle progression. Necessary for embryogenesis. Belongs to the cyclin family. Cyclin AB subfamily. | Cyclin-dependent kinase 4 homolog; Serine/threonine-protein kinase which, in association with cyclin D-like protein cyd-1, is required for the progression through the G1 phase of the cell cycle during postembryonic development by phosphorylating and inhibiting lin-35 and fzr-1. In complex with cyd-1, involved in sex determination during gonadogenesis by regulating the asymmetric division of the somatic gonadal precursor cell (SGP). | 0.983 |
cya-1 | cya-2 | ZK507.6.1 | F59H6.7.1 | G2/mitotic-specific cyclin-A1; Involved in the control of the cell cycle after S phase. May bind to and activate cdk-1 and/or cdk-2 to promote cell cycle progression. Necessary for embryogenesis. Belongs to the cyclin family. Cyclin AB subfamily. | CYCLIN domain-containing protein; Belongs to the cyclin family. | 0.551 |