STRINGSTRING
act-5 act-5 akt-1 akt-1 acdh-2 acdh-2 acdh-13 acdh-13 acdh-5 acdh-5 acdh-1 acdh-1 acdh-12 acdh-12 gpx-1 gpx-1 acdh-9 acdh-9 lpin-1 lpin-1 acdh-8 acdh-8 acdh-3 acdh-3 abl-1 abl-1 acdh-10 acdh-10 acdh-4 acdh-4 acdh-7 acdh-7 cox-4 cox-4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
act-5ACTin. (375 aa)
akt-1Serine/threonine-protein kinase akt-1; Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway. Phosphorylates Forkhead-related daf-16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their functions. Has an essential role in regulating developmental arrest at the dauer stage. Plays a role in immune function and pathogen resistance. Regulates salt chemotaxis learning. Downstream of age-1 and together with akt-2 and sgk-1, promotes cell survival during embryonic devel [...] (546 aa)
acdh-2Acyl CoA DeHydrogenase. (386 aa)
acdh-13Acyl CoA DeHydrogenase. (617 aa)
acdh-5Acyl CoA DeHydrogenase. (442 aa)
acdh-1Acyl CoA DeHydrogenase. (427 aa)
acdh-12Acyl CoA DeHydrogenase. (613 aa)
gpx-1Glutathione peroxidase 1; May constitute a glutathione peroxidase-like protective system against oxidative stresses. (163 aa)
acdh-9Acyl CoA DeHydrogenase. (409 aa)
lpin-1LNS2 domain-containing protein. (794 aa)
acdh-8Acyl CoA DeHydrogenase. (412 aa)
acdh-3Acyl CoA DeHydrogenase. (419 aa)
abl-1Tyrosine-protein kinase abl-1; Functions downstream of migratory protein mig-13 and is involved in Q neuroblast migration during larval development. Recruited by mig-13 to the leading edge of Q neuroblasts and their descendents to signal downstream, likely to the wve-1 pathway, and direct migration along the anteroposterior body axis. Promotes germline cell apoptosis in response to oxidative, osmotic and heat shock stresses. Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily. (1224 aa)
acdh-10Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family. (417 aa)
acdh-4Acyl CoA DeHydrogenase. (385 aa)
acdh-7Acyl CoA DeHydrogenase. (412 aa)
cox-4Cytochrome OXidase assembly protein. (175 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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