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dylt-3 dylt-3 osm-9 osm-9 dhc-3 dhc-3 unc-76 unc-76 dyci-1 dyci-1 che-11 che-11 dli-1 dli-1 dylt-2 dylt-2 xbx-1 xbx-1 unc-54 unc-54 dylt-1 dylt-1 che-3 che-3 dyf-1 dyf-1 osm-3 osm-3 his-24 his-24 osm-6 osm-6 rol-6 rol-6 dyrb-1 dyrb-1 osm-1 osm-1 dhc-4 dhc-4 Y37B11A.2 Y37B11A.2 pola-1 pola-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dylt-3DYnein Light chain (Tctex type). (148 aa)
osm-9ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (937 aa)
dhc-3Dynein Heavy Chain. (3275 aa)
unc-76Uncharacterized protein. (388 aa)
dyci-1WD_REPEATS_REGION domain-containing protein. (643 aa)
che-11Uncharacterized protein. (1437 aa)
dli-1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (443 aa)
dylt-2DYnein Light chain (Tctex type). (123 aa)
xbx-1X-BoX promoter element regulated. (370 aa)
unc-54Myosin-4; Required for muscle contraction. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1963 aa)
dylt-1DYnein Light chain (Tctex type). (106 aa)
che-3Cytoplasmic dynein 2 heavy chain 1; Functions as a motor for intraflagellar retrograde transport in chemosensory neurons. Functions in cilia biogenesis. Belongs to the dynein heavy chain family. (4171 aa)
dyf-1Tetratricopeptide repeat protein 30 homolog; Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip. Specifically required for the kinesin osm-3 to dock onto and move the IFT particles which contain these precursors. Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motili [...] (656 aa)
osm-3Osmotic avoidance abnormal protein 3; Kinesin motor protein which is required for the anterograde intraflagellar transport (IFT) along the middle segment of the sensory neuron cilia together with the kinesin II motor complex (composed of klp-11, klp-20 and kap-1) and on its own, is required for IFT along the distal segment. In addition, regulates the length of cilia. May have a role during neurogenesis and axonal transport. (699 aa)
his-24Histone 24; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. (208 aa)
osm-6Osm-6 protein. (472 aa)
rol-6Cuticle collagen rol-6; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Involved in body morphogenesis. (348 aa)
dyrb-1Dynein light chain roadblock; Belongs to the GAMAD family. (95 aa)
osm-1Intraflagellar transport protein osm-1; Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motility. Required for the maintenance and formation of chemosensory cilia that detect chemosensory cues. (1737 aa)
dhc-4DHC_N2 domain-containing protein. (2727 aa)
Y37B11A.2DNA polymerase. (1303 aa)
pola-1DNA polymerase. (1456 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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