STRINGSTRING
vps-2 vps-2 vps-4 vps-4 vps-25 vps-25 T24B8.2 T24B8.2 smo-1 smo-1 vps-60 vps-60 did-2 did-2 vps-20 vps-20
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
vps-2Related to yeast Vacuolar Protein Sorting factor. (237 aa)
vps-4Related to yeast Vacuolar Protein Sorting factor; Belongs to the AAA ATPase family. (430 aa)
vps-25Related to yeast Vacuolar Protein Sorting factor. (183 aa)
T24B8.2Charged Multivesicular Body Protein homolog. (411 aa)
smo-1Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] (91 aa)
vps-60Related to yeast Vacuolar Protein Sorting factor. (217 aa)
did-2Doa4-Independent Degradation, homologous to yeast Did2. (205 aa)
vps-20Related to yeast Vacuolar Protein Sorting factor. (208 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.