Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Y73B6BL.12 | cul-3 | Y73B6BL.12.1 | Y108G3AL.1a.3 | Thioredoxin; Belongs to the thioredoxin family. | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | 0.723 |
| Y73B6BL.12 | daf-16 | Y73B6BL.12.1 | R13H8.1h.1 | Thioredoxin; Belongs to the thioredoxin family. | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | 0.571 |
| Y73B6BL.12 | gpx-1 | Y73B6BL.12.1 | F26E4.12.1 | Thioredoxin; Belongs to the thioredoxin family. | Glutathione peroxidase 1; May constitute a glutathione peroxidase-like protective system against oxidative stresses. | 0.920 |
| Y73B6BL.12 | gpx-2 | Y73B6BL.12.1 | R05H10.5b.1 | Thioredoxin; Belongs to the thioredoxin family. | Glutathione peroxidase 2; May constitute a glutathione peroxidase-like protective system against oxidative stresses. | 0.859 |
| Y73B6BL.12 | gpx-3 | Y73B6BL.12.1 | C11E4.2.1 | Thioredoxin; Belongs to the thioredoxin family. | Glutathione peroxidase 3; Belongs to the glutathione peroxidase family. | 0.859 |
| Y73B6BL.12 | gpx-4 | Y73B6BL.12.1 | Y94H6A.4.1 | Thioredoxin; Belongs to the thioredoxin family. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.856 |
| Y73B6BL.12 | gpx-5 | Y73B6BL.12.1 | C11E4.1.1 | Thioredoxin; Belongs to the thioredoxin family. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.779 |
| Y73B6BL.12 | gpx-6 | Y73B6BL.12.1 | T09A12.2b.1 | Thioredoxin; Belongs to the thioredoxin family. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.822 |
| Y73B6BL.12 | gpx-7 | Y73B6BL.12.1 | R03G5.5a.1 | Thioredoxin; Belongs to the thioredoxin family. | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | 0.822 |
| Y73B6BL.12 | gpx-8 | Y73B6BL.12.1 | F55A3.5.1 | Thioredoxin; Belongs to the thioredoxin family. | Glutathione PeroXidase. | 0.823 |
| Y73B6BL.12 | hsp-70 | Y73B6BL.12.1 | C12C8.1.1 | Thioredoxin; Belongs to the thioredoxin family. | Heat Shock Protein; Belongs to the heat shock protein 70 family. | 0.929 |
| Y73B6BL.12 | skn-1 | Y73B6BL.12.1 | T19E7.2a.1 | Thioredoxin; Belongs to the thioredoxin family. | Protein skinhead-1; Transcription factor required to specify the fate of ventral blastomeres in the early embryo, and postembryonically for the development of the intestine. Directly regulates expression of zygotically expressed med-1 and med-2 to direct mesendoderm development. Required for stl-1 mRNA up- regulation in response to oxidative stress and anoxia. Required for the up-regulation of gcs-1 and several glutathione-S-transferase mRNAs in response to oxidative stress generated during pathogenic bacterial infection. In neurons, involved in mitochondrial fusion and behavioral reco [...] | 0.588 |
| Y73B6BL.12 | trx-4 | Y73B6BL.12.1 | Y44E3A.3.1 | Thioredoxin; Belongs to the thioredoxin family. | Thioredoxin; Belongs to the thioredoxin family. | 0.621 |
| Y73B6BL.12 | xbp-1 | Y73B6BL.12.1 | R74.3a.1 | Thioredoxin; Belongs to the thioredoxin family. | BZIP domain-containing protein. | 0.468 |
| akt-1 | daf-16 | C12D8.10b.2 | R13H8.1h.1 | Serine/threonine-protein kinase akt-1; Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway. Phosphorylates Forkhead-related daf-16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their functions. Has an essential role in regulating developmental arrest at the dauer stage. Plays a role in immune function and pathogen resistance. Regulates salt chemotaxis learning. Downstream of age-1 and together with akt-2 and sgk-1, promotes cell survival during embryonic devel [...] | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | 0.999 |
| akt-1 | skn-1 | C12D8.10b.2 | T19E7.2a.1 | Serine/threonine-protein kinase akt-1; Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway. Phosphorylates Forkhead-related daf-16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their functions. Has an essential role in regulating developmental arrest at the dauer stage. Plays a role in immune function and pathogen resistance. Regulates salt chemotaxis learning. Downstream of age-1 and together with akt-2 and sgk-1, promotes cell survival during embryonic devel [...] | Protein skinhead-1; Transcription factor required to specify the fate of ventral blastomeres in the early embryo, and postembryonically for the development of the intestine. Directly regulates expression of zygotically expressed med-1 and med-2 to direct mesendoderm development. Required for stl-1 mRNA up- regulation in response to oxidative stress and anoxia. Required for the up-regulation of gcs-1 and several glutathione-S-transferase mRNAs in response to oxidative stress generated during pathogenic bacterial infection. In neurons, involved in mitochondrial fusion and behavioral reco [...] | 0.967 |
| cul-3 | Y73B6BL.12 | Y108G3AL.1a.3 | Y73B6BL.12.1 | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | Thioredoxin; Belongs to the thioredoxin family. | 0.723 |
| cul-3 | rbx-1 | Y108G3AL.1a.3 | ZK287.5.2 | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | RING-box protein 1; Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate (By similarity). Essential for meiosis, mitotic chromosomal condensation and cytokinesis. Involved in histone H3 phosphorylation. | 0.999 |
| cul-3 | skn-1 | Y108G3AL.1a.3 | T19E7.2a.1 | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | Protein skinhead-1; Transcription factor required to specify the fate of ventral blastomeres in the early embryo, and postembryonically for the development of the intestine. Directly regulates expression of zygotically expressed med-1 and med-2 to direct mesendoderm development. Required for stl-1 mRNA up- regulation in response to oxidative stress and anoxia. Required for the up-regulation of gcs-1 and several glutathione-S-transferase mRNAs in response to oxidative stress generated during pathogenic bacterial infection. In neurons, involved in mitochondrial fusion and behavioral reco [...] | 0.854 |
| cul-3 | trx-4 | Y108G3AL.1a.3 | Y44E3A.3.1 | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | Thioredoxin; Belongs to the thioredoxin family. | 0.743 |
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